College of Medicine

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2026

• 3 Not started
• 278 Active
• 2728 Finished

Projects per year

Search results

• Cellular and Molecular Mechanism Underlying the Protective Role of HO-1 in Traumatic Brain Injury

  Chiu, W., Chen, Y. & Yang, L.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Heme Oxygenase-1 100%
  • alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid 52%
  • Traumatic Brain Injury 47%
  • AMPA Receptors 44%
  • Apoptosis 19%

• Cell Behaviors and Its Gene Analysis of Nerve-Like Cell on Three-Dimensional Fibrous Matrix

  Tseng, H. & Ho, Y.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • membranes 100%
  • nerves 70%
  • cells 60%
  • gene expression 50%
  • tissue engineering 32%

• Role of MMP9/iNOS/COX-2 in Macrophages/Microglia-Activated Glioma Invasion

  Chen, Y.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glioma 100%
  • Microglia 82%
  • Macrophage Activation 46%
  • Macrophages 37%
  • Astrocytoma 30%

• Translational Genomic Approaches in Endometriosis

  Tzeng, C., Huang, Y., Li, Y., Yang, W., Shen, S. & Kao, S.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • endometrium 100%
  • microRNA 90%
  • stem cells 61%
  • cell adhesion molecules 54%
  • metastasis 35%

• The Immuno-Modulatory Effects of Xanthophylls on Male Reproductive System

  Wu, T. & Huang, Y.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • xanthophylls 100%
  • selenites 79%
  • astaxanthin 76%
  • male fertility 29%
  • prostaglandin synthase 28%

• Impact of Internet Use on Sleep Quality and Autonomic Nervous System in Elementary School Children and the Effect of Cognitive Behavioral Treatment

  Chen, S., Jeng, C., Lee, H. & Shiau, F.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Autonomic Nervous System 100%
  • Internet 77%
  • Sleep 47%
  • Cognitive Behavioral Therapy 31%
  • Heart Rate 29%

• Investigation of the Feasibility of Functional Electrical Stimulation in the Treatment of Bladder Dysfunction under a Diabetic Rat Model

  Peng, C. & Chen, S.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Urinary Bladder 100%
  • Electric Stimulation 83%
  • Urinary Tract 45%
  • Neurogenic Urinary Bladder 14%
  • Anal Canal 12%

• The Characterisitc of Trapezius Surface Myography during Sleep

  Kang, J., Hu, C., Chen, S. & Tseng, S.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Superficial Back Muscles 100%
  • Myalgia 51%
  • Sleep 36%
  • Posture 8%
  • Myofascial Pain Syndromes 6%

• Statin Inhibits Pressured-Induced Rat Renal Tubular Cell Apoptosis and Tubulointerstitial Fibrosis

  Chen, T. & Chen, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 100%
  • Peroxisome Proliferator-Activated Receptors 49%
  • Pressure 46%
  • Kidney 44%
  • Nephrosis 29%

• Roles of Autophagy and Heme Oxygenases(-1, -2) in Brain Injuries: in Vivo and in Vitro Studies

  Wang, J. & Wu, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Autophagy 97%
  • Brain Injuries 62%
  • heme oxygenase-2 59%
  • Reperfusion 56%

• The Role and Molecular Mechanism of Urotensin II in Renal Disease: Focus on Tubular Injury and Renal Fibrosis

  Hsu, Y., Chen, T. & Chen, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • urotensin II 100%
  • Kidney 27%
  • Fibrosis 11%
  • Wounds and Injuries 10%
  • Renal Insufficiency 8%

• A Tmu/Nih Integrated Research Project (4-3)─ Establishment of Image Diagnosis of Mild Traumatic Brain Injury by Functional Neuroimaging

  Chen, C. & Chiang, Y.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 16%
  • N-nitrosoiminodiacetic acid 14%
  • Taiwan 8%
  • Wounds and Injuries 7%
  • Animal Models 7%

• Role of Normoxic Expression of Hypoxia Inducible Factor 1-Α and Endoplasmic Reticulum Stress Associated Protein GRP78 in the Modulation of Drug and Radioresistance Acquisition of Human Hepatoma Cell Lines

  Chiou, J. & Wu, A. T.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 1-phenyl-3,3-dimethyltriazene 100%
  • Reticulum 60%
  • Hypoxia-Inducible Factor 1 59%
  • Research Design 56%
  • Paclitaxel 47%

• Design, Synthesis and Pharmacological Evaluation of Rutaecarpine Derivatives toward Topoisomerase I

  Lin, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Evodiamine 100%
  • Antiobesity 29%
  • Drug 20%
  • Coil 18%
  • Antiinflammatory 18%

• Investigation of Chromatin Remodeling and Akt-Dependnet mTOR/S6K Mediate Thrombin-Induced IL-8/CXCL8 in Lung Epithelial Cells

  Chen, B.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Interleukin-8 100%
  • Thrombin 96%
  • Chromatin Assembly and Disassembly 43%
  • Histone Acetyltransferases 39%
  • Histone Deacetylases 34%

• Regulatory Mechanisms of Mitochondria Involved in Apoptosis, Necrosis and Autophagy in Anuclear Cells, Platelets

  Sheu, J.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Blood Platelets 100%
  • Mitochondrial Transmembrane Permeability-Driven Necrosis 53%
  • Mitochondria 40%
  • Cyclophilin D 39%
  • Apoptosis 35%

• Molecular Mechanism in Amyloid Peptide-Induced Cerebral Endothelial Cell Apoptosis---Role of HDAC and AMPK

  Hsu, M.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylases 100%
  • Acetylation 90%
  • Endothelial Cells 54%
  • Cerebral Amyloid Angiopathy 51%
  • Sirtuins 49%

• Reconstitution of Spermatogenesis from Testis Failure after Spermatogonial Stem Cells (SSC) Transplantation for Male Fertility Preservation---A Transgenic Mouse Model

  Chen, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • stem cells 100%
  • cryopreservation 35%
  • germ cells 24%
  • mice 20%
  • spermatogenesis 17%

• Studies of Folic Acid-Induced Anti-Tumor Growth Activity---Anti-Angiogensis and Anti-Cancer Cell Growth

  Lee, W.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Folic Acid 100%
  • Antiangiogenic 47%
  • Gonadal Steroid Hormone 12%
  • Antisense Oligonucleotide 11%
  • Protein 10%

• Reactions of NSAIDs (Mefenamic Acid and Diclofenac) by O3/GAC Processes---Intermediates, Pathway and Kinetic Models

  Chang, E.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • acid 100%
  • drug 86%
  • ozonation 57%
  • PPCP 35%
  • oxidation 34%

• Molecular Mechanisms of Anti-Angiogenic Effects of 3-Methylcholanthrene, an Aryl-Hydrocarbon Receptor Agonist, in Relation to Cell Proliferation, Adhesion and Migration of Endothelial Cells, and Its Therapeutic Intervention Using Resveratrol

  Juan, S.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Methylcholanthrene 100%
  • Aryl Hydrocarbon Receptors 79%
  • Resveratrol 26%
  • Xenobiotics 24%
  • PTEN Phosphohydrolase 16%

• Molecular Pathogenesis of Cerebral Neuroglia Cells on Tjps and Biabs Expressions as Well as Ups Dysfunction in Neurotoxocariasis That Develops Progressively into Alzheimer's-Like Diseases as Assessed by SP/NK-1R Inhibition

  Fan, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Substance P 100%
  • Tight Junction Proteins 74%
  • Toxocara canis 69%
  • Astrocytes 64%
  • Blood-Brain Barrier 56%

• Effects of Maternal Depressive Symptomatology on Pregnancy Outcomes and Newborn Development---How Is Paternal Psychopathology Involved?

  Chen, Y., Lin, H., Hsu, C. & Huang, K.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mothers 100%
  • Psychopathology 77%
  • Newborn Infant 75%
  • Spouses 59%
  • Pregnancy Outcome 59%

• Studies on the Mechanisms of Apple Polyphenol (Phloretin)-Induced Apoptosis in Human Breast Cancer Cells

  Wu, C. & Ho, Y.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glucose 100%
  • Antitumor 17%
  • Laser Capture Microdissection 12%
  • Phloretin 7%
  • Apoptosis Induction 7%

• Studies on the Mechanisms of A9-Nicotinic Acetylcholine Receptor Confers Tamoxifen-Induced Drug Resistance in Human Breast Cancer Cells

  Ho, Y. & Wu, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tamoxifen 100%
  • phosphopyruvate hydratase 94%
  • breast neoplasms 68%
  • nicotinic receptors 48%
  • drug resistance 35%

• Association of Peroxisome Proliferator-Activated Receptors, PPAR-Mediated Genes and Ischemic Stroke

  Chiou, H. & Hu, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 100%
  • Peroxisome Proliferator-Activated Receptors 77%
  • Genes 33%
  • Oxidized LDL Receptors 30%
  • Coenzyme A Ligases 27%

• Effect of Bright Light Therapy on Improving Sleep Disburanbce and Its Clustered Symptoms in Cancer Patients

  Lin, C., Lee, H., Shiau, F., Lai, Y. & Lin, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sleep 100%
  • Phototherapy 40%
  • Neoplasms 26%
  • Light 14%
  • Sleep Initiation and Maintenance Disorders 14%

• Studies on the Molecular Mechanism of Thrombin-Induced Connective Tissue Growth Factor (CTGF) Expression in Lung Fibroblasts

  Lin, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Connective Tissue Growth Factor 100%
  • Thrombin 61%
  • Fibroblasts 24%
  • MAP Kinase Kinase Kinase 5 20%
  • Transcription Factor AP-1 18%