College of Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 3 Not started
• 250 Active
• 3061 Finished

Projects per year

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• 探討具調節STAT訊息之真菌成分在視網膜穆勒及小神經膠細胞作用機制及其改善青光眼誘發神經性退化之療效(1/3)

  Hsiao, G.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展具化學/光熱複合療效及骨組織修復功能之奈米粒子應用於發生骨轉移之乳癌治療(2/3)

  Mi, F.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 血清轉位蛋白TSPO作為診斷標記及神經元損傷指標合併發炎反應對認知功能機制探討(1/3)

  Bai, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在國際健康功能與身心障礙分類系統的架構下，探討蛋白質補充合併運動訓練對急慢性機構衰弱老人改善肌少症指數及身體活動功能之成效(3/3)

  Liou, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展三功能抗體(EGFR/CD3/mPEG)修飾之聚乙二醇-免疫增敏奈米藥物以主動標靶毒殺大腸癌並同時強化體內T細胞於腫瘤微環境抗癌功效之創新協同療法-開發三功能抗體(EGFR/CD3/mPEG)以協同加成聚乙二醇-免疫增敏奈米藥物及T細胞於大腸癌腫瘤微環境之抗癌功效(2/3)

  Lin, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以CD3標靶微脂粒包覆免疫佐劑結合樹突狀細胞之胞外泌體應用於大腸癌免疫治療(1/3)

  Lin, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 將BTK-ITK途徑作為標靶以克服肺癌治療的抗藥性以及抑制腦轉移的策略(3/3)

  Kuo, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 高血糖症加劇登革病毒感染症的影響與機制(1/3)

  Lin, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以智慧輔助科技介入失智症照護及其社會經濟影響－以智慧輔助科技介 入失智症照護及其社會經濟影響

  Chen, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討腎臟細胞暴露於塑膠微粒和塑膠奈米中誘發自體吞噬作用和增加SREBPs並引起血管內皮細胞滲漏作用之機制(2/3)

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) 後疫時代數位病理學課程建構與線上學習學生接受度學習成效分析

  Chu, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › d - Ministry of Education

• 評估以奈米顆粒搭載抗新生血管藥物Aflibercept之眼藥水在小鼠角膜血管新生之治療效果

  Lin, I.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 魚類感覺系統在酸性環境下的功能變化-從側線到行為的探討(1/3)

  Horng, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 奈米控釋介導間質幹細胞外泌體合併細胞激素結合誘餌胜?與微囊蛋白-1支架領域胜?之三功能協同創新療法於治療肥胖併發敗血症所致器官傷害與死亡之療效: 聚焦細胞死亡相關機轉(1/2)

  Huang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Using Deep Learning to Improve Cerebrovascular Reserve Measurement from Baseline Mri

  Chen, D. C. & Li, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 硫化氫治療主動脈剝離療效透過調控Nrf2-GPX4訊息路徑抑制細胞鐵凋亡之研究

  Lu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 評估標定尼古丁乙醯膽鹼受體亞型5與FOXD1訊息傳遞軸對於抑制口腔癌放射線抗性與免疫逃脫的治療效益(1/3)

  Lin, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• A multi-modal investigation of the relationship between dopamine-serotonin signaling and intrinsic brain activity in bipolar disorder (1/3)

  Magioncalda , P.

  8/1/21 → 10/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以多重反應監測質譜分析修格連氏症患者血清中之代謝體與其疾病之關聯性的探討

  Chang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討膠質母細胞瘤外泌體中Btk/PD-L1/PD-L2 訊號途徑在腫瘤免疫所扮演的致病角色及其精準治療應用

  Lin, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 缺血性腦損傷之突破性治療策略研究-老化細胞清除療法大幅延長急性缺血性中風之治療時間限制

  Hsieh, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抑制HIF-1α蛋白質促使線粒體運鐵蛋白功能恢復以改善棕櫚酸酯誘導的胰島素抗性

  Kuo, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 樹突細胞PD-L1/PD-L2失調在COPD 異常發炎的角色及機制探討(3/3)

  Lee, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以老藥利尿劑新用為抗骨肉瘤之藥物：利尿劑對於骨肉瘤細胞存活、爬行與代謝之影響

  Su, B.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 甲狀腺荷爾蒙調控腸上皮細胞屏障與通透性的角色探討-針對甲狀腺影響腸道作用之路徑研究

  Lin, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanistic Insights Into the Therapeutic Potential of Lithium on Cardiac Remodeling: Targeting the Allostatic Load and Dysregulated Mitochondrial Bioenergetics in Rapid Eye Movement Sleep Deprivation

  Chen, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Impact of Childhood Trauma Exposure on Social Cognition in Patients with Schizophrenia – Examines the Role of Oxytocin Receptor Gene Polymorphism

  Goh, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Glyoxalase 1 基因控制對肺癌惡性肋膜積水中代謝壓力介導產生的細胞上皮間質轉化與癌轉移的影響機轉(2/3)

  Chung, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討由中草藥丹蔘衍生之單一化合物及微小核糖核酸494在肥胖引發糖尿病導致腎病變之轉譯醫學研究

  Chen, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 後生元和益生菌透過抑制炎症和調節免疫力減輕新生小鼠高氧誘導的肺損傷

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討ENO1/HMGB2調控多形性膠質母細胞瘤麩醯胺酸代謝重整及轉譯應用

  Liu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究細胞外基質膠原蛋白誘發的酸性微環境促進惡性膀胱腫瘤之角色功能探討(1/2)

  Lee, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用卵巢癌幹細胞分化模型建立漿液性卵巢上皮癌表基因分類系統

  Wen, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用人工智慧虛擬篩選平台鑑定DNA聚合酶theta之小分子抑制劑和評估其對於轉移型去勢抗性之攝護腺癌的治療效果(3/3)

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究第14 腫瘤壞死因子（TNFSF14）對粥狀動脈硬化進展、血管內皮功能及心血管疾病之影響– 從基礎到臨床

  Hsu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Metformin抑制TRPA1與P2X3受器所引發的呼吸反射及過度敏感之機制探討

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 柴油引擎廢氣粒子媒介嚴重氣喘氣道上皮層之肥大細胞活化與細胞激素釋放

  Weng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以小分子甲殼素奈米粒子建構水生魚類的核酸運輸平台

  Cheng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討牙周病對牛皮癬之影響與治療用藥策略性之研究

  Lee, A.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• TIGIT 在調節免疫拮抗點抑制劑抗藥性的角色(1/3)

  Feng, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 進展性胰臟癌新穎增進免疫療法的治療策略與生物指標-節拍式化學治療增進基質硬化性胰臟癌免疫監督與免疫檢查點阻斷療法: 聚焦於腫瘤基質與髓源性抑制細胞(3/3)

  Tsai, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抑制PCSK9對於改善心房纖維化之機轉以及治療心房纖維化引發心律不整治療之創新應用研究。(3/3)

  Chung, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討KH-Type切割調控蛋白在腎細胞癌惡性進程中所扮演的角色(2/3)

  Chien, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 辛伐他汀抗腎細胞癌的作用，經由抑制代謝重編程從mTOR、PPAR到RhoA(3/3)

  Juan, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 艾克曼嗜黏蛋白菌和電漿活化水對硫酸葡聚醣鈉誘導的潰瘍性結腸炎的保護作用：從微生物代謝產物和蛋白質以及細胞外泌體中的小分子核醣核酸觀點出發

  Chang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以資料探勘技術進行大數據分析，建立術中低血氧與術後休克風險預測模型(2/2)

  Lin, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以CRISPR/Cas9基因編輯平台發展MYC/BCL2/BCL6作為人類B細胞淋巴癌標靶精準治療模式

  Chen, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建置公衛研究專用之環境資料整合平台-Part II

  Chuang, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• β-catenin訊息路徑誘發動靜脈廔管病變之分子機轉: 預防動靜脈廔管狹窄之新型治療標的 (第二年延續計畫)

  Sue, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討藍光誘發視網膜病變中血管內皮細胞與去整合素金屬蛋白?17的病生理角色及治療策略

  Li, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology