College of Medicine

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2026

• 3 Not started
• 278 Active
• 2728 Finished

Projects per year

Search results

• Novel Activities of Gamma-Aminobutyric Acid-Mediated Regulation of Platelet Activation, Apoptosis, and Autophagy: the Non-Genomic Functions of Nf-Kappab Signal in Anucleated Cells

  Sheu, J.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • gamma-Aminobutyric Acid 100%
  • Blood Platelets 65%
  • Platelet Activation 27%
  • Mitochondrial DNA 26%
  • Autophagy 20%

• Enhancement of Immuno-Modulatory Capacity by Shear Stress in Mesenchymal Stem Cells

  Ho, J.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mesenchymal Stem Cells 100%
  • Mesenchymal Stem Cell Transplantation 21%
  • Aptitude 21%
  • Animal Disease Models 20%
  • Therapeutic Uses 13%

• 抑制SP/NK-1R的表現探討腦部神經膠質細胞對血腦屏蔽緊密連結蛋白與腦部損傷相關生物標記的表現和泛素蛋白#37238

  Fan, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Cd69 in Tnfalpha-Inhibited Erythroid Differentiation

  Huang, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Erythropoietin 100%
  • Anemia 35%
  • Hematopoietic Stem Cells 31%
  • Inflammation 31%
  • alpha-Globins 29%

• Cytotoxicity and Application on Drug Resistant Cells of Halide Derivatives of Rutaecarpine

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Evodiamine 100%
  • Poison 67%
  • Halide 66%
  • Topoisomerase Inhibitor 49%
  • Antimicrobial Agent 40%

• Detrimental Effects of an Aryl-Hydrocarbon Receptor Agonist, 3mc, on Brain Vascular Integrity and Permeability, and the Therapeutic Intervention by Statin Derivatives.

  Juan, S.

  8/1/12 → 9/30/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Aryl Hydrocarbon Receptors 100%
  • Retinoblastoma Protein 56%
  • extracellular matrix receptor 50%
  • Extracellular Matrix Proteins 49%
  • Phosphatidylinositol 3-Kinases 33%

• Epigenetic Regulation of Lps-Induced G-Csf Expression in Macrophages

  Chang, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Granulocyte Colony-Stimulating Factor 100%
  • Macrophages 19%
  • Epigenomics 17%
  • MicroRNAs 13%
  • Inflammation 11%

• Studies on the Carcinogenic Mechanisms of Histamine N-Methyltransferase-Mediated Breast Cancer Formation

  Wu, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Breast Neoplasms 18%
  • Neoplasms 6%
  • Carcinogenesis 6%

• Study of Laser Enhancement of Transdermal Delivery of Nanoparticles

  Lee, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • delivery 100%
  • antibiotics 82%
  • strata 76%
  • drugs 75%
  • lasers 71%

• Role of Er Stress in Evodiamine-Induced Apoptosis and G2/M Arrest of Human Colorectal Carcinoma Cells

  Chen, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colorectal Neoplasms 100%
  • Apoptosis 41%
  • Cyclin B1 30%
  • Proteins 16%
  • Structure-Activity Relationship 13%

• Translational Genomic Approaches in Endometriosis

  Tzeng, C., Kao, S., Huang, Y., Yang, W., Yang, W., Yeh, C., Li, Y. & Shen, S.

  8/1/12 → 10/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

  • endometrium 100%
  • microRNA 90%
  • stem cells 61%
  • cell adhesion molecules 54%
  • metastasis 35%

• Circuits of Igf-1r and Niche Signaling (Hypoxia/Inflammation) in Stem Cell Transformation and Its Clinical Implication of Molecular Target Therapy (Model of Germline Stem Cells)

  Huang, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplastic Stem Cells 100%
  • Stem Cells 86%
  • Hypoxia 55%
  • Inflammation 34%
  • Seminoma 29%

• Modulation of Tumor Microenvironment by Nucleic Acid Chimeras as a New Paradigm for Adjuvant Cancer Therapy

  Yeh, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • neoplasms 100%
  • cytokines 66%
  • neoplasm progression 60%
  • neoplasm cells 55%
  • chimerism 45%

• The Roles of Fibronectin Fragments in the Articular Chondrocytes: from Single Nucleotide Polymorphism to Functional Investigation.

  Lee, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fibronectins 100%
  • chondrocytes 59%
  • cartilage 53%
  • integrins 43%
  • osteoarthritis 23%

• A Study on Trans-Neuronal Striato-Nigral Degeneration-Induced Movement Disorders after Stroke: Evaluation with Grey Matter Suppression Ir and Diffusion Tensor Imaging( I )

  Chen, C.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Movement Disorders 100%
  • Stroke 53%
  • Diffusion Tensor Imaging 50%
  • Middle Cerebral Artery 48%
  • Gray Matter 45%

• The Novel Development of Continuous Bladder Volume Measurement System

  Chen, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • bladder 100%
  • catheters 25%
  • sensors (equipment) 22%
  • drug therapy 7%
  • urine 6%

• 轉錄因子Sp1在腦神經損傷所扮演隻角色(1/3)

  Chang, W.

  8/1/12 → 7/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• NF-kB以及NF-kB repressing factor (NRF) 在慢性阻塞性肺疾病引發系統性發炎之角色探討(3/3)

  Lee, K.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Roles of Central Orexin Activities in the Pathophysiology of Hypertension in Shr

  Hwang, L.

  8/1/12 → 9/30/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Orexins 100%
  • Orexin Receptors 97%
  • Inbred SHR Rats 57%
  • Hypertension 30%
  • Arterial Pressure 23%

• Application of Functional Electrical Stimulation on the Study of Nerve Regeneration in the Rat with Diabetic Neuropathy

  Peng, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electric Stimulation 100%
  • Nerve Regeneration 94%
  • Urinary Tract 93%
  • Diabetes Mellitus 49%
  • Nerve Fibers 45%

• Pulmonary Effects of Chorioamnionitis and Postnatal Hyperoxia in Rat Offspring

  Chen, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chorioamnionitis 100%
  • Hyperoxia 72%
  • Bronchopulmonary Dysplasia 58%
  • Renin-Angiotensin System 48%
  • Lung Injury 37%

• Mechanisms of Apelin in Electrophysiological Characteristics and Calcium Dynamics in Left Atrium and Pulmonary Vein Cardiomyocytes Underlying the Pathophysiology of Atrial Fibrillation

  Chen, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Apelin 100%
  • Pulmonary Veins 51%
  • Cardiac Myocytes 39%
  • Atrial Fibrillation 27%
  • Calcium 13%

• Novel Roles of Arnt in Breast Tumor Progression, Metastasis and Therapy

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epidermal Growth Factor 100%
  • Neoplasms 65%
  • Arachidonate 12-Lipoxygenase 45%
  • Neoplasm Metastasis 45%
  • Xenobiotics 32%

• Investigation on Developing Novel Biomarkers and Treatments in the Patients with Fibromyalgia

  Kang, J.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibromyalgia 100%
  • Transcranial Direct Current Stimulation 38%
  • Exercise 32%
  • Virtual Reality 30%
  • Biomarkers 12%

• The Integrated Theraptic Effect of the Major Components of Psidium Guajava L. Aqueous Extracts (Pe) (Gallic Acid, Quercetin, Egcg, and Rutin) Combining with Medical Trials and Control Diets on the Chronic Kidney Disease

  Chen, K.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Renal Insufficiency 100%
  • Gallic Acid 66%
  • Psidium 32%
  • Diet 27%
  • Rutin 26%

• Macro and Micro Biomechanical Studies of Soft Tissue Remodeling under Tissue Expansion (II)

  Chen, H.

  8/1/12 → 1/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tissues 100%
  • mechanical properties 29%
  • animal injuries 22%
  • clinical trials 21%
  • texture 16%

• Molecular and Cellular Mechanism of Adipocyte Modulatory Effects on Pulmonary Vein and Atrium

  Chen, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adipocytes 100%
  • Atrial Fibrillation 64%
  • Cardiac Myocytes 60%
  • Calcium 44%
  • Adipokines 37%

• The Neurotrophic/Neuroprotective Role of Gip in Cellular and Rodent Models of Mild Traumatic Brain Injury.( I )

  Lin, J. & Chen, R.

  8/1/12 → 7/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

  • Peptides 62%
  • Glucose 62%
  • Incretins 25%
  • Glucagon-Like Peptide 1 23%
  • Neuroprotection 20%

• Molecular Mechanisms Underlying Statins-Suppressed Colorectal Cancer Progression: Role of P53 Family Proteins and Microrna

  Hsu, M.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 100%
  • Simvastatin 61%
  • Colorectal Neoplasms 49%
  • MicroRNAs 43%
  • Cell Death 31%

• Evaluation of the Effects of Selective Serotonin Reuptake Inhibitor on High Grade Glioma

  Shen, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Serotonin Uptake Inhibitors 100%
  • Glioblastoma 74%
  • Blood-Brain Barrier 29%
  • Brain Neoplasms 28%
  • Cell Death 17%

• Study on the Immuno-Modulatory Effects of Notch Ligand Delta 4 on Immune Cells and in Ova-Induced Asthmatic Mice

  Lee, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Dendritic Cells 100%
  • Ligands 43%
  • Asthma 39%
  • STAT4 Transcription Factor 34%
  • Th2 Cells 23%

• Genomic and Non-Genomic Estrogen Effects on the Spinal Nr2b-Related Uterus-Colon Crosstalk in Rats

  Lin, T.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • uterus 100%
  • colon 95%
  • estrogens 62%
  • irritable bowel syndrome 33%
  • comorbidity 31%

• A Study on the Evaluation of Stromal Stem Cells and Stromal Fibroblasts in Human Tissue Regenerative and Cancer Forming Potentials

  Shih, T.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplastic Stem Cells 100%
  • Mesenchymal Stem Cells 72%
  • Stromal Cells 67%
  • Fibroblasts 59%
  • Stem Cells 59%

• Molecular Mechanisms of Propofol-Involved Protection against Ischemia Brain Injuries

  Chen, T.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Propofol 100%
  • Ischemia 76%
  • Brain Injuries 75%
  • Reperfusion 34%
  • Mitogen-Activated Protein Kinases 30%

• The Build of Functional Protein Molecular Shuttles by Using a Genetically Engineered Kinesin and Nucleic Acid Aptamers - with the Integration of the Cost-Effective Microscopic Imaging System and Micro Fluidic Channel Chips

  Kuo, T.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Kinesin 100%
  • Microtubules 50%
  • Nucleic Acids 12%
  • Adenosine Triphosphate 10%
  • Nucleotide Aptamers 9%

• Analysis the Role of Satellite Cell during Denervation Induced Muscular Atrophy and a Trail of Transplantation of Adipocyte Derived Myogenic Stem Cells.

  Chang, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • atrophy 100%
  • myogenic regulatory factors 41%
  • stem cells 38%
  • muscular atrophy 37%
  • adipocytes 27%

• Roles of Toll-Like Receptor-4 and Hif-1 in Propofol-Involved Protection against Traumatic Brain Injury-Induced Dysfunction of the Blood-Brain Barrier

  Chang, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Blood-Brain Barrier 100%
  • Propofol 73%
  • Hypoxia 36%
  • Brain Edema 25%
  • Craniocerebral Trauma 22%

• The Studies on the Mechanism of Intravenous Immunoglobulin (Ivig)-Induced Inhibitory Functions on Neutrophil Recruitments

  Chang, J.

  8/1/12 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Intravenous Immunoglobulins 100%
  • Leukocyte Rolling 38%
  • Leukocytes 25%
  • Neutrophil Infiltration 23%
  • E-Selectin 12%

• Effect of Sumoylation on Gsk-3beta-Mediated Autophagy

  Shih, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycogen Synthase Kinases 100%
  • Autophagy 81%
  • Cadmium 42%
  • Sumoylation 39%
  • Small Interfering RNA 19%

• 探討鎮靜藥物dexmedetomidine保護腦血管免於缺血-再灌流傷害之機轉: 細胞和動物研究

  Wu, G.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies of Molecular and Cellular Underlying Mechanisms of Ferrous Citrate-Induced Cerebral Vasospasm and Brain Injury

  Lee, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Subarachnoid Hemorrhage 100%
  • monoferrous acid citrate 89%
  • Intracranial Vasospasm 74%
  • Brain Injuries 53%
  • Thioredoxins 49%

• Characterization of Molecular and Pathological Role of Hs 1-Associated Protein X-1(Hax-1) in Cisplatin Induced Nephorotoxicity via Hax-1 Conditional Knock out Mice

  Lin, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cisplatin 100%
  • Kidney 45%
  • Knockout Mice 31%
  • Renal Insufficiency 22%
  • Wounds and Injuries 16%

• Degradation of Nitrogen-Containing PPCPs: Kinetic Study, Application, and Balancing the Toxicity of N-DBP and Intermediates through Bioassay

  Chang, E.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • PPCP 100%
  • chlorination 35%
  • ozonation 26%
  • nitrogen 24%
  • byproduct 21%

• Effects of Indoor Air Quality Improvement on Cardiovascular Health in General Population

  Chuang, K.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Indoor Air Pollution 100%
  • Air Pollution 15%
  • Taiwan 13%
  • Cardiovascular System 13%
  • Quality Improvement 13%

• Molecular Mechanisms of Alpha 9-Nicotinic Acetylcholine Receptor (Alpha 9-Nachr)-Mediated Trastuzumab (Herceptinr) Drug Resistance in Breast Cancer Cells

  Ho, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Liposomes 66%
  • MicroRNAs 56%
  • Trastuzumab 53%
  • Nicotinic Receptors 49%

• 晚期乳癌組織中尼古丁受體(α9-nAChR)表現與Trastuzumab (Herceptin®)產生抗藥性之分子機制探討

  Ho, Y.

  8/1/12 → 7/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Translational Studies of Mycobacterium Tuberculosis-Induced Lung and Pleural Fibrosis

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Connective Tissue Growth Factor 100%
  • Mycobacterium tuberculosis 57%
  • Fibroblasts 34%
  • Lung 31%
  • Pulmonary Fibrosis 28%

• The Effects of Atherosclerosis Progression in Circulating Ferritin in Community-Based Population

  Bai, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • blood samples 100%
  • blood pressure 88%
  • cardiovascular disease 88%
  • chronic illness 69%
  • examination 40%

• Oxidative Stress and Bisphenol a Impact on the Women with Polycystic Ovary Syndrome

  Hsu, M.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • oxidative stress 100%
  • woman 65%
  • reactive oxygen species 61%
  • disturbance 47%
  • gamete 45%

• Involvement of Glycosphingolipids and Toll-Like Receptors in Response to Helicobacter Pylori Infection in Gastric Epithelial Cells

  Lin, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Helicobacter pylori 100%
  • Helicobacter Infections 61%
  • Stomach 41%
  • Ceramides 40%
  • Epithelial Cells 32%