College of Medicine

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2026

• 3 Not started
• 278 Active
• 2728 Finished

Projects per year

Search results

• The Association between Maternal Sleep Disturbances and the Health Condition of Their Offspring: a Secondary Data Analysis and a Longitudinal Cohort Study( I )

  Lee, H.

  8/1/16 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mothers 100%
  • Sleep Deprivation 92%
  • Child 51%
  • Sleep 50%
  • Child Health 38%

• Investigation of the Mechanism of Post-Fracture Immune Dysfunction and the Role of Statin in Its Prevention and Treatment Strategy: from Bench to Bedside(2/2)

  Lin, J. A.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Wounds and Injuries 100%
  • MicroRNAs 80%
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 77%
  • 3' Untranslated Regions 65%
  • Immunosuppression 57%

• Risk Assessment and Predictive Model of Potentially Ineffective Care of Patients in Intensive Care Units - Analysis Using Taiwan National Health Insurance Research Database

  Chen, T.

  8/1/16 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Intensive Care Units 100%
  • Preexisting Condition Coverage 48%
  • National Health Programs 42%
  • Health Expenditures 40%
  • Taiwan 39%

• Electroacupunture Relieves Pelvic Pain by Antagonizing MeCP2-Dependent Epigenic Modification of BDNF Mediates Estrogen-Fasciliated Uterus-Colon Crosstalk in Rats(2/3)

  Lin, T.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Methyl-CpG-Binding Protein 2 100%
  • Brain-Derived Neurotrophic Factor 60%
  • Urethra 56%
  • Colon 46%
  • Histones 37%

• The Role of Cysteine Cathepsins in Suppressing the Peroxisome Proliferator-Activated Receptor R (Pparr) Co-Activator 1a (Pgc-1a) Expression in the Process of Skeletal Muscle Atrophy and Development of Preclinical Therapeutics Model

  Kuo, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cathepsins 100%
  • Muscular Atrophy 85%
  • Skeletal Muscle 67%
  • Cathepsin L 59%
  • Cysteine 40%

• Preparation Mechanism and Application of Innovatively Plasmon-Induced Activated Liquid Water with Reduced Hydrogen-Bonded Structure(2/3)

  Liu, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hot Electron 100%
  • Antiaging 75%
  • Hydrogen Bond 63%
  • Dialyzer 53%
  • Metal Nanoparticle 52%

• Study on the Developmnt and Application of Nuclear Medical Assessment Model for Brain Inflammation by Angiostrongylus Cantonesis Infection

  Cheng, P.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • positron-emission tomography 100%
  • image analysis 40%
  • eosinophils 38%
  • brain 34%
  • infection 25%

• The Molecular Basis, Preventive Efficacy of Angiotension II Receptor Blockade and Quality of Life in Marfan Syndrome

  Chiu, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Marfan Syndrome 100%
  • Fibrillin-1 35%
  • Losartan 28%
  • Dilatation 19%
  • Quality of Life 15%

• Gene Knock out Mice Model for Studying the Molecular Mechanisms of Early Onset Breast Tumor Microenvironment Regulation.(2/3)

  Wu, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antitumor 100%
  • Growth Factor 25%
  • Apoptotic 24%
  • Cell Death 23%
  • Hormone 21%

• Sequential Delivery of Gene Therapy and Chemotherapeutic Agents to the Rat Brain Malignant Glioma by Using Drug-Loaded Nanofibrous Membranes

  Tseng, Y.

  8/1/16 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Nanofibers 100%
  • Carmustine 85%
  • Temozolomide 63%
  • Glioblastoma 50%
  • Membranes 30%

• Cellular and Molecular Mechanisms with Epigenetic Regulation by Histone Deacetylation on Postopratetive Atrial and Pulmonary Vein Arrhythmogenesis

  Chen, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylases 100%
  • Atrial Fibrillation 85%
  • Pulmonary Veins 63%
  • Calcium 44%
  • Heart Atria 40%

• Pathophysiology of Macrophage Migration Inhibitory Factor on Electrical and Structural Remodelings in Heart Failure-Induced Atrial Arrhythmogenesis

  Chen, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Heart Failure 100%
  • Atrial Fibrillation 95%
  • Atrial Remodeling 81%
  • Histone Deacetylases 68%
  • Pulmonary Veins 44%

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • inter-alpha-inhibitor 82%
  • Particulate Matter 74%
  • Inflammation 30%
  • human ITIH4 protein 25%

• The Role of Amyloid-Beta in the Late-Onset Post-Stroke Vascular Cognitive Impairment( II )

  Hu, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Investigation of Anti-Microglia/Macrophage Mechanisms of Different Tak1/Tabs Regulators and Their Protective Effects in Intracerebral Hemorrhage and Brain Abscess

  Hsiao, G.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MAP kinase kinase kinase 7 100%
  • Cerebral Hemorrhage 28%
  • Brain Abscess 28%
  • Microglia 22%
  • Macrophage Activation 15%

• Studied the Roles of Grp94 in the Progression and Metastasis of Esophageal Squamous Carcinoma, Mechanism Dissection, and Drug Development

  Chang, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Esophageal Neoplasms 100%
  • glucose-regulated proteins 96%
  • Squamous Cell Carcinoma 17%
  • Neoplasms 15%
  • Endoplasmic Reticulum Stress 15%

• 臺美(US)國合計畫－腦傷害的新診斷和新治療之轉譯研究－Thalidomide新衍生藥與p53新抑制劑用於治療急性腦創傷:投藥 途徑、劑量效果及多重機制之探討(2/3)

  Wang, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Research Personnel 62%
  • pifithrin 60%
  • Thalidomide 47%
  • Therapeutic Uses 31%

• Study on the Roles of Unfolded Protein Response and Ubiquitin-Proteasome System in Radiotherapy Using Nanoparticle Drug Delivery in Triple-Negative Breast Cancer

  Chiu, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Triple Negative Breast Neoplasms 100%
  • tubacin 87%
  • Endoplasmic Reticulum Stress 51%
  • Nucleotide Aptamers 40%
  • Proteasome Endopeptidase Complex 38%

• A Preclinical Study of the Therapeutic Targeting of Inflammatory-Cytokine-Addicted Cancer Stem Cells in Advanced Pancreatic Cancer

  Tsai, K. K.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Clinical Effects of Deep Oscillation Massage in Treating Fibromyalgia

  Kang, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibromyalgia 100%
  • Massage 46%
  • Vibration 42%
  • Therapeutics 13%
  • Pain 13%

• 利用PLA2G6基因嵌入小鼠研究第十四型帕金森病分子病理機轉與治療(1/3)

  Yeh, T.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以全結構去細胞方式進行氣管移植與取代的組織工程置換物之嘗試(2/2)

  Hung, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • trachea (vertebrates) 100%
  • cartilage 77%
  • sonication 70%
  • tissues 27%
  • skeleton 25%

• Spatio-Temporal Variations of Dengue Outbreaks in Taiwan

  Chuang, T.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Dengue 100%
  • Disease Outbreaks 97%
  • Taiwan 54%
  • Vector Borne Diseases 30%
  • Spatio-Temporal Analysis 15%

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatitis B virus 100%
  • Hepatocellular Carcinoma 65%
  • Hep G2 Cells 23%
  • Hepatitis B 21%
  • Neoplasms 19%

• 幹細胞基礎研究與前臨床動物試驗

  Huang, Y.

  8/1/16 → 7/31/17

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Study on the Mechanism of Streptococcal Pyrogenic Exotoxin B-Caused Defective Efferocytosis for Modulating Pro-Inflammatory Responses and Immune Evasion in Group a Streptococcal Infection

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • erythrogenic toxin 100%
  • Protein S 53%
  • Streptococcus 33%
  • streptopain 12%
  • Anti-Inflammatory Agents 9%

• The Effects and Molecular Mechanisms of Phthalates (DEHP 和DBP) on the Mitochondrial Function and Genetic Regulation in Ovarian Granulosa Cells and Mouse Embryo(2/2)

  Tzeng, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • phthalates 100%
  • granulosa cells 23%
  • reproductive system 17%
  • mice 14%
  • embryo (animal) 10%

• Impact of Calcitriol on Fibroblast Growth Factor-23 (Fgf-23) Signaling in Diabetic Dysregulation in Cardiac Fatty Acid and Glucose Metabolism

  Lee, T.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fibroblast growth factor 23 100%
  • Calcitriol 77%
  • Peroxisome Proliferator-Activated Receptors 33%
  • Fatty Acids 28%
  • Diabetes Mellitus 22%

• 探討SPNS2對於決定個體缺氧耐受性的影響(3/3)

  Yang, C. H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • phenotype 100%
  • therapeutics 58%
  • neurodegenerative diseases 48%
  • pathophysiology 46%
  • arteries 37%

• Anxiety, Depression and Coronary Spasm: a Synthesis of Epidemiological and Experimental Studies

  Hung, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Spasm 100%
  • Coronary Vessels 78%
  • Anxiety 22%
  • Coronary Artery Disease 22%
  • Depression 17%

• The Physiological Predictors of Concurrent Cardiovascular Diseases in Schizophrenia(1/2)

  Chen, P.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• CXCL5/CXCR2/JNK Axis Is the Shared Pathway of Neuroinflammation and Microvascular Damage That Contributes to White Matter Injury in the Immature Brain(3/3)

  Huang, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • White Matter 100%
  • Brain Injuries 57%
  • Blood-Brain Barrier 40%
  • JNK Mitogen-Activated Protein Kinases 38%
  • Leukocytes 33%

• A Multi-Sensitive Chitosan Nanomicelles for Targeted Anticancer Drug Delivery

  Mi, F.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chitosan 100%
  • Hyaluronic Acid 93%
  • Sodium Nitrite 51%
  • Deacetylation 47%
  • Pluronic 45%

• Development of efficient immunoglobulin G analytical method for investigating autoantibody biomarkers for pancreatic disease

  Tsai, I.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Characterization of Thalamocortical Dysrhythmia in Mild Traumatic Brain Injury Using Simultaneous Mri and Eeg Measurements and Pre-Clinical N-Acetylcysteine Treatment Response

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Acetylcysteine 44%
  • Post-Concussion Syndrome 17%
  • Neuroimaging 15%
  • Electroencephalography 14%
  • Atrophy 9%

• Molecular Mechanism of the Effect of Cafestol on Growth Factor-Induced Cardiomyocyte Hypertrophy

  Liu, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • cafestol 100%
  • Cardiac Myocytes 57%
  • urotensin II 55%
  • Hypertrophy 48%
  • Cardiomegaly 38%

• Targeting Class III Phosphoinositide 3-Kinase (Pi3k) for Anticancer Drug Discovery

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphoinositide 100%
  • 3-Methyladenine 41%
  • Antineoplastic Agent 32%
  • Protein Synthesis 25%
  • LY294002 22%

• The Alteration of Inflammatory Reflex and Its Association with Psychotropic Drugs in Bipolar Disorder from Acute Mania to Full Remission(2/2)

  Tsai, S.

  8/1/16 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Bipolar Disorder 100%
  • Reflex 82%
  • Cholinergic Agents 32%
  • Psychological Power 21%
  • Antipsychotic Agents 21%

• Anti-Tumor Mechanisms of the Novel Series of Aliphatic Hydroxamate Derivatives, Wmj-J Compounds

  Hsu, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • WMJ-S-001 100%
  • Neoplasms 73%
  • Colorectal Neoplasms 66%
  • Acetylation 65%
  • HCT116 Cells 53%

• Transgenerational Epigenetic Reprogramming of Neuronal Maturation by Early-Life Maternal Sleep Deprivation( I )

  Yang, C. H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Maternal Deprivation 100%
  • Sleep Deprivation 86%
  • Epigenomics 63%
  • Sleep 32%
  • Puberty 22%

• Relationships of One-Carbon Cycle Pathways with Psychopathology and Metabolic Abnormalities in Patients with Schizophrenia and Potential Intervention Strategy with 5-Methyltetrahydrofolate and Vitamin B12(3/3)

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Folic Acid 100%
  • Vitamin B 12 69%
  • Carbon Cycle 66%
  • Schizophrenia 51%
  • 5-methyltetrahydrofolate 48%

• Study the Function and Regulation of Mirnas in Pancreatic Cancer Progression( III )

  Huang, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Vulnerability and Resilience: a Matched Case-Control Study of Psychosocial and Psychiatric Factors for Deliberate Self-Harm of Taiwanese Indigenous Peoples

  Liu, I.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Self-Injurious Behavior 100%
  • Psychiatry 30%
  • Suicide 18%
  • Indigenous Peoples 14%
  • Psychology 13%

• Establishment of a Biophysical Effect-Based Platform for Rapid Expansion of Functional Mesenchymal Stem Cells

  Ho, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • stromal cells 100%
  • stem cells 79%
  • cell transplantation 46%
  • microfluidic technology 39%
  • shear stress 32%

• 以胜肽為基礎之細胞激素結合誘餌療法於治療敗血症之療效及其調控發炎、氧化、凋亡、自嗜與發炎小體之作用探討(1/3)

  Huang, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Impact of Angiogenic Growth Factors on Inflammation and Microvasculature in Renal Fibrosis

  Chang, F.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effect of Ph on Mechanotransduction of Hair Cell -- Role of Calcium-Sensing Receptor (Casr)

  Horng, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Calcium-Sensing Receptors 100%
  • Inner Ear 18%
  • Zebrafish 17%
  • Embryonic Structures 13%
  • Inner Auditory Hair Cells 11%

• Urinary Total Arsenic Levels, Arsenic Methylation Capacity, Plasma Selenium Concentrations and Genetic Polymorphisms of Glutathione Peroxidase and Selenoprotein and Prostate Cancer

  Hsueh, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • arsenic 100%
  • prostatic neoplasms 78%
  • selenium 48%
  • selenoproteins 39%
  • glutathione peroxidase 27%

• Contextualization of Acgme Milestone Project and Its Integration with Entrustable Professional Activities (Epas) in Taiwan – a 3-Stage Educational Implementation in Anesthesiology Based on 4 Teaching Hospitals

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Taiwan 100%
  • educational reform 41%
  • learning 40%
  • content analysis 29%
  • expert 25%

• 探討短鏈脂肪酸抑制造成過敏作用之免疫細胞的調控機制及其對過敏性氣喘疾病之治療特性評估(3/3)

  Lee, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Volatile Fatty Acids 100%
  • Phenylbutyrates 29%
  • Mast Cells 27%
  • Immunoglobulin E 20%
  • Asthma 17%