College of Medicine

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022

• 2 Not started
• 215 Active
• 2674 Finished

Projects per year

Search results

• The Causes and Courses of Insomnia---Case-Control and Follow-up Study

  Lee, H., Hsu, R. & Kang, J.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sleep Initiation and Maintenance Disorders 100%
  • Sleep 24%
  • Organized Financing 18%
  • Arousal 15%
  • Case-Control Studies 12%

• Mechanisms and Clinical Applications of Transcranial Direct Current Stimulation in Treating Patients with Firbomyalgia

  Kang, J., Chen, S. & Lee, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibromyalgia 100%
  • Transcranial Direct Current Stimulation 57%
  • Serotonin and Noradrenaline Reuptake Inhibitors 11%
  • Hyperalgesia 8%
  • Hydrotherapy 6%

• Study of Anti-Αlpha-Enolase I Antibodies on Cancers and Their Potential Applications

  Yang, Y. & Leu, S.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphopyruvate Hydratase 100%
  • Antibodies 32%
  • Single-Chain Antibodies 13%
  • Neoplasms 10%
  • Proteins 9%

• Gene Polymorphism of Fatty Acids Metabolism Enzymes in Elderly Patients with Depression and Mild Cognitive Impairment

  Huang, S. & Lee, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cognitive Dysfunction 100%
  • Elderly 82%
  • Depression 79%
  • Apolipoprotein E2 61%
  • Fatty Acids 52%

• New Drug Development for Mtbi

  Chiu, W., Chiang, Y. & Hsu, F.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Herbal Medicine 68%
  • Wounds and Injuries 49%
  • Migraine Disorders 40%
  • Oxazoles 36%

• In Vivo and in Vitro Studies of Progesterone-Induced Anti-Angiogenesis

  Lee, W.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • angiogenesis 100%
  • sex hormones 60%
  • progesterone 42%
  • blood vessels 33%
  • atherosclerosis 22%

• Effect of Sumoylation on Gsk-3beta-Mediated Autophagy

  Shih, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycogen Synthase Kinases 100%
  • Autophagy 81%
  • Cadmium 42%
  • Sumoylation 39%
  • Small Interfering RNA 19%

• To Explore the Influence of Chlamydia Pneumoniae Groel in Endothelial Progenitor Cells.

  Lin, F.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chlamydophila pneumoniae 100%
  • Endothelial Progenitor Cells 46%
  • Pneumonia 30%

• Statin Inhibits Pressured-Induced Rat Renal Tubular Cell Apoptosis and Tubulointerstitial Fibrosis

  Chen, T. & Chen, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 100%
  • Peroxisome Proliferator-Activated Receptors 49%
  • Pressure 46%
  • Kidney 44%
  • Nephrosis 29%

• The Role of Micrornas in Cutaneous Wound Healing

  Shen, S.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Wound Healing 52%
  • Skin 44%
  • Vascular Endothelial Growth Factors 11%
  • Cell Proliferation 9%

• Effect of Bright Light Therapy on Improving Sleep Disburanbce and Its Clustered Symptoms in Cancer Patients

  Lin, C., Shiau, F., Lai, Y., Lin, C. & Lee, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sleep 100%
  • Phototherapy 40%
  • Neoplasms 26%
  • Light 14%
  • Sleep Initiation and Maintenance Disorders 14%

• Detrimental Effects of an Aryl-Hydrocarbon Receptor Agonist, 3mc, on Brain Vascular Integrity and Permeability, and the Therapeutic Intervention by Statin Derivatives.

  Juan, S. & Hwang, L.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Aryl Hydrocarbon Receptors 100%
  • Retinoblastoma Protein 56%
  • extracellular matrix receptor 50%
  • Extracellular Matrix Proteins 49%
  • Phosphatidylinositol 3-Kinases 33%

• Reactions of NSAIDs (Mefenamic Acid and Diclofenac) by O3/Gac Processes: Intermediates, Pathway and Kinetic Models

  Chang, E.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • acid 100%
  • drug 86%
  • ozonation 57%
  • PPCP 35%
  • oxidation 34%

• Jak/Stat and Casein Kinase Signaling Pathway Are Involved in Interleukin-6-Induced Ctgf Expression and Lung Fibrosis

  Lin, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Superoxides 100%
  • Neutrophils 66%
  • methionyl-leucyl-phenylalanine 40%
  • Poisons 31%
  • Oxygen 30%

• Translational Genomic Approaches in Endometriosis

  Tzeng, C., Huang, Y., Shen, S., Yang, W., Li, Y., Yeh, C. & Kao, S.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • endometrium 100%
  • microRNA 90%
  • stem cells 61%
  • cell adhesion molecules 54%
  • metastasis 35%

• Role of Normoxic Expression of Hypoxia Inducible Factor 1-Α and Endoplasmic Reticulum Stress Associated Protein Grp-78 in the Modulation of Drug-And Radioresistance Acquisition of Human Hepatoma Cell Lines

  Chiou, J. & Wu, T. A.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 1-phenyl-3,3-dimethyltriazene 100%
  • Reticulum 60%
  • Hypoxia-Inducible Factor 1 59%
  • Research Design 56%
  • Paclitaxel 47%

• The integrated theraptic effect of the major components of Psidium guajava L. aqueous extracts (PE) (gallic acid, quercetin, EGCG, and rutin) combining with medical trials and control diets on the chronic kidney disease

  Chen, K. & Peng, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Renal Insufficiency 100%
  • Gallic Acid 66%
  • Psidium 32%
  • Diet 27%
  • Rutin 26%

• Studies of Cxcl12 in Hypoxia-Induced Pulmonary Fibrosis

  Chen, B. & Chung, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hypoxia 100%
  • Pulmonary Fibrosis 65%
  • Fibroblasts 61%
  • Lung 57%
  • Phosphatidylinositol 3-Kinases 37%

• Effects of Tashinon IIA on Angiotensin II-Induced Vascular Smooth Muscle Cell Proliferation

  Chan, P. & Cheng, T.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tashinone IIA 100%
  • Angiotensin II 66%
  • Smooth Muscle Myocytes 52%
  • Vascular Smooth Muscle 33%
  • Renin-Angiotensin System 17%

• Application of Functional Electrical Stimulation on the Study of Nerve Regeneration in the Rat with Diabetic Neuropathy

  Peng, C. & Chen, S.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electric Stimulation 100%
  • Nerve Regeneration 94%
  • Urinary Tract 93%
  • Diabetes Mellitus 49%
  • Nerve Fibers 45%

• The studies on the mechanism of intravenous immunoglobulin (IVIG)-induced inhibitory functions on neutrophil recruitments

  Chang, J. & Chang, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Intravenous Immunoglobulins 100%
  • Leukocyte Rolling 38%
  • Leukocytes 25%
  • Neutrophil Infiltration 23%
  • E-Selectin 12%

• The Roles of Micrornas in Endothelin-1 and Hypoxia-Induced Ctgf Production

  Chen, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Endothelin-1 59%
  • Hypoxia 31%
  • Fibrosis 29%
  • Lung 23%

• Community's Prevalence of Silent Brain Infarction and the Association between Inflammatory Markers, Polymorphisms and Silent Brain Infarction

  Bai, C., Chen, W. & Chen, K.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Brain Infarction 100%
  • Interleukin-6 23%
  • Single Nucleotide Polymorphism 10%
  • Arteries 8%
  • Stroke 8%

• Association of Peroxisome Proliferator-Activated Receptors, PPAR-Mediated Genes and Ischemic Stroke

  Chiou, H. & Hu, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 100%
  • Peroxisome Proliferator-Activated Receptors 77%
  • Genes 33%
  • Oxidized LDL Receptors 30%
  • Coenzyme A Ligases 27%

• Mechanisms of Apelin in Electrophysiological Characteristics and Calcium Dynamics in Left Atrium and Pulmonary Vein Cardiomyocytes Underlying the Pathophysiology of Atrial Fibrillation

  Chen, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Apelin 100%
  • Pulmonary Veins 51%
  • Cardiac Myocytes 39%
  • Atrial Fibrillation 27%
  • Calcium 13%

• Role of Sp-Family in Lung Tumorigenesis

  Chang, W.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lung 100%
  • Lung Neoplasms 73%
  • Carcinogenesis 61%
  • Doxycycline 61%
  • Neoplasms 43%

• Toxic Effects of Topical Agents through Transdermal Delivery

  Lee, W.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • antibiotics 100%
  • strata 92%
  • delivery 86%
  • cornea 86%
  • drugs 73%

• The Study of Apoptosis, Inflammation, Autophagy and Organ Functions in Rat Liver Following Hemorrhagic Shock and Protective Mechanism of Ligustrazine.

  Chen, R. & Wang, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Reperfusion Injury 100%
  • tetramethylpyrazine 93%
  • Liver 85%
  • Autophagy 69%
  • Hemorrhagic Shock 61%

• Effects of N-3 Pufas on Endothelial Cell Migration and Angiogenesis Induced by Prostate Cancer Cells

  Pai, M.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Polyunsaturated Fatty Acid 100%
  • Conditioned Culture Medium 15%
  • Docosahexaenoic Acid 14%
  • Lipopolysaccharide 11%
  • Drop 9%

• Study of Mechanosensitive Transduction Channel on Hair Cell of Zebrafish

  Horng, J.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Zebrafish 100%
  • Transient Receptor Potential Channels 63%
  • FM1 43 59%
  • Inner Ear 53%
  • Morpholinos 48%

• Molecular Pathogenesis of Cerebral Neuroglia Cells on TJPs and Biabs Expressions as Well as UPS Dysfunction in Neurotoxocariasis That Develops Progressively into Alzheimer's-Like Diseases as Assessed by SP/NK-1R Inhibition

  Fan, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Substance P 100%
  • Tight Junction Proteins 89%
  • Toxocara canis 69%
  • Astrocytes 64%
  • Blood-Brain Barrier 56%

• The Translational Characterization of the Role of Wnt/Beta-Catenin/Tcf Signaling in the Generation of Invasive and Chemoresistant Cancer Stem Population in Liver Cancer

  Lee, W. & Yeh, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplastic Stem Cells 100%
  • Liver Neoplasms 85%
  • beta Catenin 71%
  • Side-Population Cells 47%
  • Drug Resistance 14%

• Circuits of IGF-1R and Niche Signaling (Hypoxia/Inflammation) in Stem Cell Transformation and Its Clinical Implication of Molecular Target Therapy (Model of Germline Stem Cells)

  Huang, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplastic Stem Cells 100%
  • Stem Cells 86%
  • Hypoxia 55%
  • Inflammation 34%
  • Seminoma 29%

• Preparation and Application of New Type Matrix for Cell Sheet Engineering Use

  Tseng, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Systems engineering 100%
  • Cell culture 86%
  • Membranes 84%
  • Monomers 79%
  • Tissue 57%

• CAAT/enhancer binding protein beta訊息路徑參與thrombin誘導人類肺部上皮細胞IL-8/ CXCL8表現之研究

  Chen, B.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

• Characterization of Zebrafish Dnaja3a and Dnaja3b Genes Function during the Embryonic Developmental Stages

  Chow, J.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Zebrafish 100%
  • Embryonic Development 90%
  • Catenins 41%
  • Apoptosis 39%
  • Genes 39%

• Endothelin-1 Mediates Fibrocyte Differentiation in Chronic Obstructive Asthma

  Lin, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Asthma 100%
  • Fibrosis 76%
  • Myofibroblasts 73%
  • Lung 61%
  • Connective Tissue Growth Factor 51%

• Molecular Mechanisms of Helicobacter Pylori Virulence Factors for Regulating Inflammation Responses in Epithelial Cells and Macrophages

  Lin, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Helicobacter pylori 100%
  • pylorus 80%
  • macrophages 74%
  • inducible nitric oxide synthase 44%
  • cholesterol 36%

• Novel Activities of Gamma-Aminobutyric Acid-Mediated Regulation of Platelet Activation, Apoptosis, and Autophagy: the Non-Genomic Functions of Nf-Kappab Signal in Anucleated Cells

  Sheu, J.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • gamma-Aminobutyric Acid 100%
  • Blood Platelets 65%
  • Platelet Activation 27%
  • Mitochondrial DNA 26%
  • Autophagy 20%

• The Influences and Underlying Mechanisms of Differentiation and Proliferation in Ox-Ldl and Hdl-Stimulated Human Late-Outgrowth Endothelial Progenitor Cells.

  Huang, C., Lin, F., Lin, F. & Shyu, K.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Endothelial Progenitor Cells 100%
  • erucylphosphocholine 98%
  • Endothelium 28%
  • HDL Lipoproteins 25%
  • Dyslipidemias 23%

• The Immuno-Modulatory Effects of Xanthophylls on Male Reproductive System

  Wu, T. & Huang, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • xanthophylls 100%
  • selenites 79%
  • astaxanthin 76%
  • male fertility 29%
  • prostaglandin synthase 28%

• Auditory Processing of Acoustic Cues for Prosodic Recognition

  Lin, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cues 100%
  • Child 53%
  • Cochlear Implants 51%
  • Acoustics 35%
  • Neuronal Plasticity 25%

• Artificial Neural Network Modeling to Predict the Severity of Oxygen Desaturation and Improve the Nocturnal Hypoxemia after General Anesthesia in Patients with Morbid Obesity

  Lin, C. & Chiu, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Oxygen 100%
  • Hypoxia 94%
  • General Anesthesia 90%
  • Positive-Pressure Respiration 46%
  • Bariatric Surgery 44%

• Studies on the Carcinogenic Mechanisms of Histamine N-Methyltransferase-Mediated Breast Cancer Formation

  Wu, C. & Ho, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Breast Neoplasms 18%
  • Neoplasms 6%
  • Carcinogenesis 6%

• Studies on the Mechanisms of a9-Nicotinic Acetylcholine Receptor Confers Tamoxifen-Induced Drug Resistance in Human Breast Cancer Cells

  Ho, Y. & Wu, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tamoxifen 100%
  • phosphopyruvate hydratase 94%
  • breast neoplasms 68%
  • nicotinic receptors 48%
  • drug resistance 35%

• Effects of Maternal Depressive Symptomatology on Pregnancy Outcomes and Newborn Development---How Is Paternal Psychopathology Involved?

  Chen, Y., Hsu, C., Lin, H. & Huang, K.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mothers 100%
  • Psychopathology 77%
  • Newborn Infant 75%
  • Spouses 59%
  • Pregnancy Outcome 59%

• Enrich the Study of Biomedical Research Equipment to Enhance the Energy Plan - the Building Plan of Time of Flight - Secondary Ion Mass Spectrometer for Core Facilities of Biomedical Research

  Mai, F., Chang, J. & Chang, C.

  6/1/11 → 5/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • biomedical research 100%
  • image analysis 97%
  • metabolomics 69%
  • spectrometers 37%
  • research equipment 27%

• Evaluation on prevention for metabolic syndrome and diabetes mellitus through lifestyle modification intervention in pre-diabetic subjects (100-104)

  Chiou, H., Tang, C., Bai, C., Yang, S., Su, C., Su, C., Liou, T., Wang, S., Chen, J., Hsieh, A. & Huang, C.

  5/4/11 → 5/3/12

  Project: A - Government Institution › c - Ministry of Health and Welfare

• Study the Bacteria Species of Pneumonia and Early Detect the Pathogen from Expired Gas by Electronic Nose

  Shih, C.

  5/1/11 → 4/30/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electronic Nose 100%
  • Pneumonia 35%
  • Sputum 34%
  • Air 28%
  • Medicine Chests 15%

• 保健功效之免疫調節之研究

  Shang, H.

  4/1/11 → 3/31/12

  Project: B - Project of TMU › i - Other (Funded by TMU)