College of Medicine

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 2 Not started
• 231 Active
• 3024 Finished

Projects per year

Search results

• The Role of SUV39H1 in Control of Inflammatory Genes and in Chronic Inflammation of Copd

  Lee, K., Feng, P. & Chuang, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Inflammation 60%
  • Blood Cells 33%
  • Histone Deacetylase 2 32%
  • Glucocorticoids 27%

• Study of Expression and Functional Mechanisms of Histamine N-Methyltransferase (HNMT) in Tumorigenesis and Correlation with Progression in Lung Cancer

  Wang, L., Lee, W., Ho, Y. & Wu, A. T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Lung Neoplasms 43%
  • Carcinogenesis 18%
  • Neoplasms 10%
  • Genes 9%

• The Role of Inflammatory Gene Polymorphisms on Risk of Post-Stroke Vascular Dementia (I)

  Chiou, H., Chi, N., Lin, H., Wu, C., Hsieh, F., Hu, C. & Hsieh, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 93%
  • Cognitive Dysfunction 89%
  • Blood Vessels 52%
  • Inflammation 36%
  • Whole Exome Sequencing 16%

• The Effect and Mechanisms of Chemotherapy in Recruit Inflammatory Cells into Tumor Microenvironment of Lung Cancer Patients

  Feng, P. & Lee, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Myeloid-Derived Suppressor Cells 100%
  • Neoplasms 26%
  • Tumor Microenvironment 25%
  • Lung Neoplasms 19%
  • Drug Therapy 19%

• Effects of Central Neuromodulation with Functional Electrical Stimulation on Bladder Functions in Traumatic Brain Injured Rats

  Peng, C., Chen, S. & Hsieh, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Deep Brain Stimulation 100%
  • Traumatic Brain Injury 76%
  • Brain 29%
  • Urinary Bladder 27%
  • Urination 19%

• A Toxicological Assessment of Air Pollution in the Vicinity of a Petrochemical Complex

  Chuang, H. & Lee, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Particulate Matter 100%
  • Taiwan 54%
  • Toxicology 44%
  • Risk Assessment 38%
  • Methionine 19%

• Short-Chain Fatty Acids Act as Anti-Allergic Regulators on Immune Effector Cells and Exert Immune-Modulatory Effects on Ovalbumin-Induced Allergic Diseases in Mice

  Lee, Y. & Hsiao, G.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Volatile Fatty Acids 100%
  • Phenylbutyrates 27%
  • Mast Cells 25%
  • Immunoglobulin E 19%
  • Asthma 16%

• Study of Expression and Functional Mechanisms of Histone 3 K4 Demethylase JARID1B in Tumorigenesis and Correlation with Progression in Lung Cancer

  Kuo, K., Wang, L. & Yeh, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lung Neoplasms 100%
  • Histones 46%
  • Carcinogenesis 42%
  • Neoplasms 24%
  • Genes 22%

• Whole Organ Decellularizationtrachea Scaffold Tissue Engineering for Whole Segment Tracheal Transplantation/Replacement

  Hung, S., Lee, F. & Tseng, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • trachea (vertebrates) 100%
  • cartilage 77%
  • sonication 70%
  • tissues 27%
  • skeleton 25%

• Motion-Sensitive MR Imaging in Characterizing Brain Compliance in Cerebral Venous Hypertension: A Translational Study between Humans and Rats

  Lu, C., Liu, H., Chen, C. & Tsai, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Brain 100%
  • Cerebrospinal fluid 69%
  • Magnetic resonance 62%
  • Compliance 52%
  • Imaging techniques 46%

• Anti-Aging Effect with the Associated Mechanism by PRP (Platelet-Rich Plasma) in Cartilage---A Fibronectin Fragment Model

  Lee, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fibronectins 100%
  • cartilage 63%
  • Toll-like receptor 2 58%
  • osteoarthritis 50%
  • chondrocytes 42%

• Effects of Home-Based Exercise Training on Fatigue, Sleep Disturbance, Symptom Distress and Quality of Life in End-Stage Renal Disease Patients

  Lin, C., Chen, C., Lin, Y. & Wu, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Exercise 100%
  • Chronic Kidney Failure 90%
  • Quality of Life 77%
  • Sleep 53%
  • Dialysis 43%

• Investigation of Nuclear microRNA Signatures and Their Functional Effects on Glioblastoma Multiforme Pathology

  Chen, K. & Shih, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Glioblastoma 67%
  • Temozolomide 54%
  • Glioma 23%
  • Genes 12%

• Brain Function for Evaluating Post Stroke Recovery Following Robot-Assisted Gait Training and Transcranial Direct Current Stimulation

  Lai, C., Chen, C., Chen, S., Peng, C., Kang, J. & Lin, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Transcranial Direct Current Stimulation 100%
  • Rehabilitation 95%
  • Stroke 63%
  • Gait 29%
  • Neuroimaging 28%

• Repositioning Drug Therapies for Traumatic Brain Injury

  Chiu, W., Chang, C. & Chiang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Wounds and Injuries 37%
  • Dipeptidyl-Peptidase IV Inhibitors 33%
  • Incretins 33%
  • Acetylcysteine 28%

• Gene Knock out Mice Model for Studying the Molecular Mechanisms of Early Onset Breast Tumor Microenvironment Regulation.

  Wu, C., Ho, Y. & Tu, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antitumor 100%
  • Growth Factor 25%
  • Apoptotic 24%
  • Cell Death 23%
  • Hormone 21%

• Genomic, Epigenomic and Epiproteomic Analysis of Etk/Bmx Traumatic Brain Injury

  Chen, K., Chiang, Y. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Protein Kinases 15%
  • Epigenomics 14%
  • Tec protein-tyrosine kinase 14%
  • Inflammation Mediators 10%

• Effect of HMGA2 in Chemotherapy Response of Colorectal Cancer Patients with Different APC Status (II)

  Yen, Y., Cheng, Y. & Wei, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Investigate the Role of SPNS2 in Determining Individual Susceptibility to Hypoxic Challenge

  Yang, C. H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phenotype 100%
  • Pharmacology 55%
  • Physiological Adaptation 54%
  • Middle Cerebral Artery Infarction 45%
  • Neurodegenerative Diseases 36%

• The Protective Effect of PLZF Nuclear Translocation against Advanced Glycation End Product-Induced Endothelial Injury in Diabetes and Its Molecular Mechanism

  Chen, C. & Hsu, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Promyelocytic Leukemia Zinc Finger Protein 100%
  • Protein Transport 32%
  • Human Umbilical Vein Endothelial Cells 27%
  • Advanced Glycation End Products 26%
  • Autophagy 17%

• TMU103-AE1-B31

  Feng, P.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Arsenic Methylation Capacity, Methylenetetrahydrofolate Reductase and Dna Methylation Gene Polymorphisms, Plasma Selenium Concentration and Selenoprotein Gene Polymorphisms and Renal Cell Carcinoma

  Hsueh, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Arsenic 100%
  • Renal Cell Carcinoma 80%
  • Methylenetetrahydrofolate Reductase (NADPH2) 50%
  • Methylation 45%
  • Selenoproteins 39%

• Electrophysiological Activity and Functional Correlates in Female Pelvic Floor Muscles

  Yang, J., Huang, W. & Yang, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • muscles 100%
  • urinary incontinence 51%
  • electromyography 38%
  • muscle contraction 36%
  • testing 5%

• Role of HBX and IL-6 in Regulating SENP1/Stemness Properties of HBV-Related HCC under Hypoxia and Its Clinical Implication

  Huang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Interleukin-6 100%
  • Hepatocellular Carcinoma 94%
  • Hypoxia 55%
  • Drug Resistance 32%
  • Neoplasms 30%

• Establish the Research Platform for Studying Triple-Negative Breast Tumor Microenvironment Regulation---The Hyaluronan Synthase-3 Mediated Antitumor Effects as an Example

  Ho, Y. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Gene Expression 46%
  • Tumor Microenvironment 40%
  • Hyaluronan Synthases 30%
  • Fibroblasts 29%

• Studies on the Role of ORMDL3 in Thrombin-Induced IL-8/CXCL8 Expression and Airway Inflammation

  Chen, B.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Orosomucoid 100%
  • Thrombin 74%
  • Interleukin-8 34%
  • Transcription Factor AP-1 26%
  • Asthma 23%

• Pitx2c Modulations on Atrial Fibroblast Activity, Electrical Characteristic, and Myocyte-Fibroblast Interaction: Implications in the Genesis of Atrial Fibrillation

  Kao, Y. & Chen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibroblasts 100%
  • Atrial Fibrillation 36%
  • Electrophysiology 26%
  • Angiotensin II 22%
  • Cardiac Myocytes 21%

• Dose Effect of Extended-Release Metformin on Metabolic Parameters and Neurocognitive Function Treated by Clozapine or Olanzapine in Patients with Schizophrenia---A Randomized, Double-Blinded, Placebo-Controlled Trial

  Lu, M. & Chen, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Metformin 100%
  • Olanzapine 32%
  • Clozapine 31%
  • Placebos 22%
  • Schizophrenia 21%

• Role of Calcium-Sensing Receptor (CaSR) in Mechanotransduction of Hair Cell

  Horng, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Calcium-Sensing Receptors 100%
  • Zebrafish 23%
  • Neomycin 18%
  • Calcium-Transporting ATPases 18%
  • Inner Ear 16%

• Relationship between Lumbar Vertebral Perfusion and Fat Marrow Content in Normal Subjects, Osteoporosis and Bone Metastases Using DCE-MRI and Fat-Water Separation

  Chan, W. P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Perfusion 100%
  • Bone Marrow 87%
  • Fats 39%
  • Osteoporosis 35%
  • Neoplasm Metastasis 32%

• TMU103-AE1-B33

  Wu, D.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Copy Number Alterations and Transcriptome Profile Analyses Reveal Genetic Determinants Contributing to Higher Paclitaxel-Resistance of Ovarian Clear Cell Adenocarcinoma

  Chang, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Clear Cell Adenocarcinoma 100%
  • Paclitaxel 91%
  • Transcriptome 22%
  • Cell Movement 20%
  • Signal Transduction 19%

• TMU103-AE1-B30

  Fang, T.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• TMU103-AE1-B35

  Huang, T.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Steroid and Antihistamin Synergize to Inhibit Rat’s Tracheal Smooth Muscle Contractility and Its Possible Mechanisms

  Wang, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Smooth Muscle 100%
  • Histamine Antagonists 82%
  • Trachea 73%
  • levocetirizine 71%
  • Glucocorticoids 64%

• 研究合併E1A基因和表皮生長因子受體酪氨酸激?抑制劑在三重陰性乳癌臨床前治療的嶄新策略(1/3)

  Su, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Roles of Central OX2R Activities in the Pathophysiology of Hypertension in SHR

  Hwang, L.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Orexin Receptors 100%
  • Paraventricular Hypothalamic Nucleus 54%
  • Inbred SHR Rats 50%
  • Hypertension 43%
  • Neurons 34%

• Roles of inflammatory cytokines-mediated cell death and angiogenesis in ER(先期補助)

  Hsu, M.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• The Role of VEGF Isoform Change in Progressive Renal Fibrosis

  Chang, F.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Microvascular Rarefaction 100%
  • Vascular Endothelial Growth Factor A 96%
  • Kidney 93%
  • Pericytes 76%
  • Protein Isoforms 60%

• The Inhibitory Effect of Fucoidan on Renal Fibrosis

  Chen, T. & Chen, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fucoidan 100%
  • Fibrosis 40%
  • Kidney 38%
  • Chronic Renal Insufficiency 19%
  • Catenins 15%

• Chronic Obstructive Pulmonary Disease Modulate Electrophysiological Properties and Arrhythmogenesis of Pulmonary Vein and Atrium

  Lin, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Atrial Fibrillation 76%
  • Atrial Remodeling 12%
  • Volition 11%
  • Atrial Flutter 10%

• Study the Function and Regulation of miRNAs in Pancreatic Cancer Progression (II)

  Huang, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Regular Exercise on Emotional Control and Cognitive Function of Prefrontal-Limbic Pathway in Sleep-Deprived Rats---An Analysis by Behavior and Neurostructural Correlates

  Hsu, C. & Chang, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sleep Deprivation 100%
  • Limbic System 76%
  • Cognition 47%
  • Blood-Brain Barrier 46%
  • Electrolytes 35%

• 褪黑激素對人類甲狀腺球蛋白誘發的橋本氏甲狀腺炎動物模式的影響

  Lin, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Impact of Functional Connectivity MR Imaging Study in the Correlation of the Surgical Outcome Validations and Neuroplasticity of Lumbar Spinal Stenosis with Neurogenic Intermittent Claudication

  Huang, T.

  8/1/14 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Intermittent Claudication 100%
  • Spinal Stenosis 39%
  • Brain 26%
  • Neuronal Plasticity 22%
  • Chronic Pain 14%

• Pre-Clinical Evaluation of the Tumor Suppression Effectiveness and Mechanism of Small Molecule Drugs in Oral Cancer

  Chen, Y. & Wu, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pharmaceutical Preparations 100%
  • Mouth Neoplasms 70%
  • Pharmaceutical Databases 22%
  • Neoplasm Genes 17%
  • Biological Products 15%

• Molecular Ivestigation of the Electron Transfer Flavoprotein Dehydrogenase Mutation Induced Mitochondrial Dysfunction and Metabolic Defects

  Kao, S. & Hsu, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • acyl-CoA dehydrogenase 100%
  • flavoproteins 97%
  • electron transfer 79%
  • droplets 39%
  • myoblasts 31%

• TMU102-AE1-B20

  Hsieh, C.

  8/1/13 → 7/31/16

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• An Investigation of the Combined Administration of Cholesterol-Lowering Agents and Anti-Diabetic Drugs on Cell Migration Inhibition of Anaplastic Thyroid Cancer Cells

  Hsu, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Anaplastic Thyroid Carcinoma 100%
  • Drug Combinations 32%
  • Troglitazone 22%
  • Lovastatin 20%
  • Neoplasms 12%

• Redox Modulation of Protein Phosphatases by Protein Carbonylation/De-Carbonylation Process in Arterial Neointimal Hyperplasia

  Hsieh, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphoprotein Phosphatases 100%
  • Protein Carbonylation 84%
  • Oxidation-Reduction 47%
  • Protein Tyrosine Phosphatases 35%
  • Hyperplasia 31%