College of Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 3 Not started
• 246 Active
• 3056 Finished

Projects per year

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• Finished

  金屬細懸浮微粒在慢性阻塞性肺病的第二型肺泡上皮細胞Yap/Taz調控衰老機轉之研究(2/3)

  Chuang, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究黑色素瘤中Dicer與嘌呤代謝對dacarbazine化療敏感性之角色

  Lee, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展具化學/光熱複合療效及骨組織修復功能之奈米粒子應用於發生骨轉移之乳癌治療(2/3)

  Mi, F.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 雙極症患者單核球和巨噬細胞活化與血管粥狀化的關聯性: 頸動脈超音波的個案對照研究(1/3)

  Tsai, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以新式片狀細胞工學製備自體片狀心肌細胞及其應用在缺血性心臟病的動物模式-後期

  Tseng, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Metformin抑制TRPA1與P2X3受器所引發的呼吸反射及過度敏感之機制探討

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究第14 腫瘤壞死因子（TNFSF14）對粥狀動脈硬化進展、血管內皮功能及心血管疾病之影響– 從基礎到臨床

  Hsu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• T細胞耗竭在腎臟移植患者中所扮演的角色

  Wu, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 洗腎患者使用非類固醇抗發炎藥物與手術後併發症之相關性

  Lee, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 正常子宮內膜BHLHE22亞型應用於子宮內膜癌分子分型之研究

  Liew, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• A multi-modal investigation of the relationship between dopamine-serotonin signaling and intrinsic brain activity in bipolar disorder (1/3)

  Magioncalda , P.

  8/1/21 → 10/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討去磷酸?PP4在柴油排放粒子誘導嚴重過敏性發炎反應中的角色(1/3)

  Yang, F.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以多重反應監測質譜分析修格連氏症患者血清中之代謝體與其疾病之關聯性的探討

  Chang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 轉錄因子Sp1在癌細胞抗藥性所扮演角色-HDACs/Sp1-microRNA-106b~25軸在膠質母細胞瘤抗藥性扮演的角色(3/3)

  Chen, R.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討低氧微環境腫瘤外泌體與發炎細胞激素IL-6於B型肝炎病毒誘導肝癌表現多能性幹細胞基因OCT4與TKI抗藥性之調控機制與其臨床意義

  Huang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用單細胞定序解析腦膜淋巴系統於年輕和老年腦中風之調控機制

  Lee, G.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抗伺機性與多重抗藥性金黃色葡萄球菌之犬蛔蟲重組胜肽之建構、表現和治療效果

  Fan, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanistic Insights Into the Therapeutic Potential of Lithium on Cardiac Remodeling: Targeting the Allostatic Load and Dysregulated Mitochondrial Bioenergetics in Rapid Eye Movement Sleep Deprivation

  Chen, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 藉由研究腫瘤異質性來克服治療引發的癌細胞幹細胞特性及治療抵抗性(1/2)

  Lo, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結核菌感染臨床免疫組庫建立:探勘免疫球蛋白於結核菌感染之保護機制與臨床轉譯應用(3/3)

  Tsai, I.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 針對IL-33/ST2訊息路徑調控鈣平衡、內質網壓力與粒線體功能作為心房與肺靜脈心律不整活性與心房顫動致病機轉及治療策略探討(2/3)

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用輸卵管上皮類器官培養技術開發卵巢癌早期偵測之表基因生物標記(2/3)

  Lai, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 魚類感覺系統在酸性環境下的功能變化-從側線到行為的探討(1/3)

  Horng, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 認知功能缺損長者的平衡控制與動作策略：三維動作分析以及穿戴式雙重任務訓練裝置之開發及其於居家介入之成效(第二、三期)(2/2)

  Kuan, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 慢性腎臟病之日夜週期失序(2/3)

  Wu, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發血吸蟲蟲卵抗原中標的抗原蛋白作為抑制肺部發炎藥物及成分分析與機制研究

  Cheng, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在具放射治療抗性神經膠質母細胞癌的細胞中尋找MicroRNA (miR-671-5p)控其高細胞移動特性、癌症幹細胞特性及遠隔效應，並搭配人工智慧軟體開發基因調控資料庫加強免疫治療策略

  Lin, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Glyoxalase 1 基因控制對肺癌惡性肋膜積水中代謝壓力介導產生的細胞上皮間質轉化與癌轉移的影響機轉(2/3)

  Chung, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 玻尿酸包埋kaempferol的奈米粒子治療膝關節骨性關節炎的研究

  Lee, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 副甲狀腺素藉由SFRP2導致動靜脈廔管病變之惡化 – 預防動靜脈廔管不成熟之新治療標的 (第二年延續計畫)

  Liu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• BSP相似重複序列家族蛋白在草綠色鏈球菌所引起的感染性心內膜炎中細菌逃避免疫攻擊及生物膜形成所扮演的角色及機制探討(3/3)

  Jung, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 甲基乙二醛經ChREBP/SREBP1造成腎小管脂毒性進而調控PGC1/SIRT3導致電子傳遞鏈缺陷之糖尿腎病進展-探討水飛薊素(Silybin)合併Metformin之逆轉潛能

  Chen, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 自體免疫心肌炎引起心室心律不整及鈣離子調控失衡、粒線體異常與NLRP3/MIF發炎體訊息路徑活化之致病機轉及治療策略探討(1/3)

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 子宮內膜間質肉瘤之分子機轉及生物標記研究

  Kao, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 奈米控釋介導間質幹細胞外泌體合併細胞激素結合誘餌胜?與微囊蛋白-1支架領域胜?之三功能協同創新療法於治療肥胖併發敗血症所致器官傷害與死亡之療效: 聚焦細胞死亡相關機轉(1/2)

  Huang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以小分子甲殼素奈米粒子建構水生魚類的核酸運輸平台

  Cheng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 創新電漿活化水製備表面增強拉曼散射活性基材(3/3)

  Liu, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• (教學實踐) 後疫時代數位病理學課程建構與線上學習學生接受度學習成效分析

  Chu, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › d - Ministry of Education

• 在慢性阻塞性氣喘中double cortin like kinase 1 (DCLK1)在thrombin誘導IL-8/CXCL8表現及氣道發炎的病理角色之研究(2/3)

  Chen, B.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討EZH2在嚴重氣喘中媒介纖維化蛋白表現及呼吸道纖維化之機轉(2/3)

  Lin, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抑制PCSK9對於改善心房纖維化之機轉以及治療心房纖維化引發心律不整治療之創新應用研究。(3/3)

  Chung, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討YqiC蛋白特性以開發標靶抗生素並針對沙門氏菌抗生素抗藥性和侵襲性進行基因分析：以雙面向方法發展對抗沙門氏菌感染之新策略(3/3)

  Fang, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 膠淋巴系統於混合型失智症之角色(2/2)

  Hu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討BHLHE22在子宮內膜癌生成之角色

  Huang, R.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 血中的纖維細胞在嚴重氣喘患者扮演第二型細胞激素嶄新的細胞來源其臨床相關性與調控機制(2/3)

  Kuo, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 辛伐他汀抗腎細胞癌的作用，經由抑制代謝重編程從mTOR、PPAR到RhoA(3/3)

  Juan, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究BTK/HER2信號通路在HER2陽性乳腺癌生物特性角色: 調控T細胞的效應及逆轉賀癌平抗藥性的分子機制(3/3)

  Chao, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 整合虛擬實境與穿戴式感測的智慧醫療抗認知衰弱研究

  Chang, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討惡性肥胖病人在接受減重手術前後，腸胃道菌叢變化與減重效果、相關疾病改善狀況的關聯性及其調控機制

  Wang, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展三功能抗體(EGFR/CD3/mPEG)修飾之聚乙二醇-免疫增敏奈米藥物以主動標靶毒殺大腸癌並同時強化體內T細胞於腫瘤微環境抗癌功效之創新協同療法-開發三功能抗體(EGFR/CD3/mPEG)以協同加成聚乙二醇-免疫增敏奈米藥物及T細胞於大腸癌腫瘤微環境之抗癌功效(2/3)

  Lin, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology