College of Medicine

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 2 Not started
• 231 Active
• 3024 Finished

Projects per year

Search results

• b - Ministry of Science and Technology

  A Translational Study to Verify Roles of Circulating Mir-19b and Mir-93 as Biomarker Signatures for Early Diagnosis of Osteoporosis in Men(2/3)

  Chen, R.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在慢性阻塞性氣喘中double cortin like kinase 1 (DCLK1)在thrombin誘導IL-8/CXCL8表現及氣道發炎的病理角色之研究(1/3)

  Chen, B.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 金屬細懸浮微粒在慢性阻塞性肺病的第二型肺泡上皮細胞Yap/Taz調控衰老機轉之研究(2/3)

  Chuang, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Preclinical Study of the Therapeutic Targeting of Inflammatory-Cytokine-Addicted Cancer Stem Cells in Advanced Pancreatic Cancer

  Tsai, K. K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Carotid Atherosclerosis and Cardiac Function Measured by Ultrasonography in Bipolar Mania and Their Relevent Clinical Factors(2/3)

  Tsai, S.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 調節第一型神經衍生孤兒核受體 (Neuron-derived orphan receptor 1, NOR-1)之蛋白質表現可能是 Pomalidomide對創傷性腦損傷之神經保護作用之一

  Chen, R.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Care-Based Innovative Networking for Active Ageing( II )

  Lin, C.

  7/1/17 → 6/30/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigations of Adjuvant Drugs in Improving Efficacy of Nk Cell-Based Immunotherapy for Lung Cancer through Comprehensively Transcriptome Profile Analyses

  Shih, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎性結構天然物萘醌衍生物於血管及淋巴管新生抑制與抗腫瘤之應用及其機轉探討(2/3)

  Huang, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of Rich Platelets Plasma and Alginate Encapsulated Synovial Fluid Mesenchymal Stem Cells for Repairing the Partial Tear of Cruciate Ligament

  Chen, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • ligaments 100%
  • synovial fluid 81%
  • mesenchymal stromal cells 80%
  • alginates 55%
  • hydrogels 24%

• 肝醣合成酉每激酉每3於登革病毒感染單核吞噬細胞的潛在角色(2/3)

  Lin, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular and cellular mechanism of adipocyte modulatory effects on pulmonary vein and atrium

  Chen, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adipocytes 100%
  • Atrial Fibrillation 64%
  • Cardiac Myocytes 60%
  • Calcium 44%
  • Adipokines 37%

• To Identify Whether Ion Conductance Dysfunction Is an Early Electrophsiological Biomarker of Polyneuropathy in Diabetic Patients: a Longitudinal Study of Nerve Excitability in Diabetic Patients

  Sung, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neural Conduction 100%
  • Diabetic Neuropathies 69%
  • Ions 24%
  • Biomarkers 19%
  • Polyneuropathies 17%

• Effects of Propofol on Traumatic Brain Injury-Induced Insults to the Mouse Blood-Brain Barrier and Its Possible Mechanisms

  Chang, H. & Chen, R.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Propofol 90%
  • Blood-Brain Barrier 73%
  • Brain Edema 28%
  • Craniocerebral Trauma 16%

• Molecular Pathogenesis of Cerebral Neuroglia Cells on TJPs and Biabs Expressions as Well as UPS Dysfunction in Neurotoxocariasis That Develops Progressively into Alzheimer's-Like Diseases as Assessed by SP/NK-1R Inhibition

  Fan, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Substance P 100%
  • Tight Junction Proteins 74%
  • Toxocara canis 69%
  • Astrocytes 64%
  • Blood-Brain Barrier 56%

• Studying on the Mechanism and Translational Application of Blocking the Protein-Protein Interaction between Galpha-H and Plc-Delta1 in Combating Drug-Resistance and Metastasis of Triple-Negative Breast Cancer

  Lin, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Triple Negative Breast Neoplasms 100%
  • Drug Resistance 40%
  • Proteins 28%
  • Peptide Fragments 19%
  • Neoplasm Metastasis 18%

• Develop the Novel Small Molecular Inhibitor to Target Angiogenesis and the Tumor Microenvironment for Primary and Recurrent Gbm Patient( I )

  Huang, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Role of Stomatin-Like Protein 2 (Stoml2) in Thrombin-Stimulated Il-8/Cxcl8 Expression and Airway Inflammation(2/3)

  Chen, B.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role and Molecular Mechanisms of N-Α-Acetyltransferase in Driving Tumor Invasion and Metastasis of Osteosarcoma

  Chien, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • osteosarcoma 100%
  • gelatinase A 66%
  • metastasis 59%
  • neoplasms 30%
  • acetyltransferases 21%

• Investigation on the Improvenment of Solanum Nigrum and Paris Polyphylla for Inhibitions of Metastasis and Drug Resistance Mediated by Exosomes from Breast Cancer Cells

  Tai, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Drug 100%
  • Antineoplastic Agent 84%
  • Marker 83%
  • MicroRNA 58%
  • Protein 19%

• Biomarkers for the Early Prediction and Prognosis for Colorectal Cancer---Construction of Kinetic

  Chang, W. & Wei, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colorectal Neoplasms 100%
  • Calcium Channels 40%
  • Calcium 34%
  • Biomarkers 24%
  • Podosomes 18%

• 在慢性阻塞性氣喘中double cortin like kinase 1 (DCLK1)在thrombin誘導IL-8/CXCL8表現及氣道發炎的病理角色之研究(2/3)

  Chen, B.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎性苯並咪唑衍生物MFB之抗多型性神經膠質母細胞瘤之藥理活性評估與機轉探討

  Huang, S.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• RAB3C對大腸直腸癌之抗藥性與腫瘤免疫反應影響之探討(2/3)

  Chen, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Telekaryophagy, an Novel Entire Nucleus Elimination Programme in the Liver and Mammary Gland: Exploring Its Role in Genomic Stability and Physiopathology (2/3)

  Chao, H.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 自體免疫心肌炎引起心室心律不整及鈣離子調控失衡、粒線體異常與NLRP3/MIF發炎體訊息路徑活化之致病機轉及治療策略探討(1/3)

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Association of Aldh2 Gene Family Mutations with Osteoporosis and Sarcopenia: in Vi Tro, in Vi Vo, and Database Study

  Wu, M.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Exploring the Barriers and Overcome Strategies on the Way to Choosing Wisely (1/3)

  Chen, C.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular and Cellular Mechanism of Adipocyte Modulatory Effects on Pulmonary Vein and Atrium

  Chen, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adipocytes 100%
  • Atrial Fibrillation 64%
  • Cardiac Myocytes 60%
  • Calcium 44%
  • Adipokines 37%

• Study of Prevention, Control, Genotyping and Risk Factors of Intestinal Parasitic Infections and Head Lice in Schoolchildren in Cambodia(2/3)

  Liao, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Deep Learning-based analysis with Multi-Omics data for prognosis prediction of Prostate Cancer

  Chang, T.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Utilizing Artificial Intelligence Vi Rtual Screening Platform to Identify a Small-Molecule Inhibitor of Dna Polymerase Theta and Estimating Its Therapeutic Effectiveness on Metastatic Castration-Resistant Prostate Cancer

  Lin, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Molecular Pathogenesis of Doublecortin Like Kinase Protein 1 (Dclk1)/Notch1-Regulated Circulating Fibrocyte Activation in Severe Asthma( I )

  Lin, C.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 血管內皮β-catenin活化於動靜脈廔管狹窄之角色

  Sue, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 絲氨酸/蘇氨酸蛋白激酶(SIK3)參與乳癌致癌過程的分子機制探討

  Chen, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of ADAM 17 in Hypoxia-Induced CTGF Expression and Pulmonary Fibrosis (III)

  Chen, B.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • ADAM17 Protein 100%
  • Connective Tissue Growth Factor 83%
  • Hypoxia 49%
  • Small Interfering RNA 38%
  • Fibrosis 17%

• The Anti-Tumor Mechanisms of a Novel Aliphatic Hydroxamate, WMJ-S-001---Targeting Tumor Angiogenesis and Lymphangiogenesis

  Hsu, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • WMJ-S-001 100%
  • Lymphangiogenesis 25%
  • Neoplasms 15%
  • Endothelial Cells 14%
  • Vascular Endothelial Growth Factor A 9%

• Studies on the Role of ORMDL3 in Thrombin-Induced IL-8/CXCL8 Expression and Airway Inflammation

  Chen, B.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Orosomucoid 100%
  • Thrombin 74%
  • Interleukin-8 34%
  • Transcription Factor AP-1 26%
  • Asthma 23%

• The New Therapeutic Strategy of 2, 3, 5, 4’-Tetrahydroxystilbene-2-O-Β-D-Glucoside (Thsg) Derivatives on Human Dental Pulp Stem Cells-Based Periodontal Treatment(3/3)

  Lee, S.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • resveratrol 100%
  • stem cells 59%
  • therapeutics 55%
  • tooth pulp 53%
  • cell proliferation 42%

• 以照護為本的活力展齡創新結盟(1/3)

  Lin, C.

  7/1/16 → 9/30/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects and Mechanisms of Pitx2c Modulation for Atrial Electrophysiological and Structural Remodelings in Heart Failure

  Kao, Y. & Chen, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Heart Failure 100%
  • Atrial Fibrillation 64%
  • Electrophysiology 45%
  • Methylation 43%
  • MicroRNAs 40%

• The Development of the Translational System of Health Literacy in Stroke Rehabilitation (Healer): a Study of Prediction Model Validation and Interventional Effectiveness Assessment

  Hou, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke Rehabilitation 100%
  • Health Literacy 77%
  • Literacy 32%
  • Stroke 29%
  • Organizational Efficiency 12%

• Study on Dclk1-Mediated Epithelial-Mesenchymal Transition Conducing to Type 2-Biased Immune Responses in Severe Asthma( I )

  Chen, C.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Primase, DNA, polypeptide 1（PRIM1)參與吸菸所誘發乳癌形成機制及臨床轉譯研究(1/3)

  Chen, L.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Interleukin-6 Signaling in Colorectal Cancer Progression---The Causal Roles of Epithelial- and Endothelial-to-Mesenchymal Transition

  Hsu, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epithelial-Mesenchymal Transition 100%
  • Interleukin-6 94%
  • Colorectal Neoplasms 66%
  • Endothelial Cells 42%
  • Umbilicus 42%

• The Role of Aspm-Wnt Signaling in Hepatoma Cancer Stemness and Progression and the Development of the Related Nano- and Gene-Therapy(2/3)

  Tsai, K. K.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 闡明SPOCK1/PI3K/AKT訊息路徑在透明細胞腎細胞癌對舒尼替尼抗藥性的潛在機制

  Lee, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 金屬細懸浮微粒在慢性阻塞性肺病的第二型肺泡上皮細胞Yap/Taz調控衰老機轉之研究(1/3)

  Chuang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 加強血基質氧化酶的基因與蛋白質表現是3,6-Dithiopomalidomide對腦創傷所引發急性肺損傷的保護機制之一

  Chuang, H.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合奈米診斷治療、影像免疫基因圖譜與人工智慧於原發性與再復發膠質母細胞瘤之研究-開發新穎結構小分子抑制劑用來抑制血管生成和腫瘤微環境以治療原發性及復發性多型性神經膠質母細胞腦瘤患者(3/3)

  Huang, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology