College of Medicine

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2026

• 3 Not started
• 283 Active
• 2718 Finished

Projects per year

Search results

• New Drug Development for Mtbi

  Chiu, W., Chiang, Y. & Hsu, F.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Herbal Medicine 68%
  • Wounds and Injuries 49%
  • Migraine Disorders 40%
  • Oxazoles 36%

• New Brain Cortical Electrical Stimulation Technology for the Neurorehabilitation Therapy of Bladder Dysfunction in the Parkinson’S Disease Animal Model(2/3)

  Peng, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• New Brain Cortical Electrical Stimulation Technology for the Neurorehabilitation Therapy of Bladder Dysfunction in the Parkinson’S Disease Animal Model

  Peng, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• New Brain Cortical Electrical Stimulation Technology for the Neurorehabilitation Therapy of Bladder Dysfunction in the Parkinson’S Disease Animal Model

  Peng, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Neuroprotective Effects of Sig-1R-Znf179-Sp1 Pathway on Brain Injury

  Chang, W. & Chuang, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • sigma-1 receptor 100%
  • Traumatic Brain Injury 50%
  • Hydrogen Peroxide 31%
  • Neuroprotective Agents 19%
  • Wounds and Injuries 12%

• Neuroprotective Effects of Sig-1r-Znf179-Sp1 Pathway on Brain Injury

  Chang, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • sigma-1 receptor 100%
  • Traumatic Brain Injury 55%
  • Hydrogen Peroxide 35%
  • Neuroprotective Agents 21%
  • Wounds and Injuries 13%

• Neural and Glutamatergic Correlates of Resting State Activity and Stimulus-Induced Activity in Major Depressive Disorder---Can Multimodal Imaging (fMRI and MRS) Reveal Therapeutic Predictors?

  Chen, C., Lane, T. J., Hu, C., Tseng, Y. & Lee, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Major Depressive Disorder 100%
  • Magnetic Resonance Spectroscopy 53%
  • Magnetic Resonance Imaging 42%
  • Multimodal Imaging 42%
  • Gyrus Cinguli 33%

• Nano-Scaffolds Enhance the Survival Rate of Immature Cryopreserved Testicular Tissue in Transplantation - Transgenic Mouse Model

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • immatures 100%
  • tissue engineering 84%
  • image analysis 60%
  • spermatogenesis 55%
  • banking 51%

• Nanocarriers for Drug Delivery Conjugated with Specific Aptamer for Potential Use in Membranous Nephropathy

  Lin, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Resveratrol 100%
  • Membranous Glomerulonephritis 99%
  • Phospholipase A2 Receptors 94%
  • Nanoparticles 88%
  • Inflammasomes 85%

• Mri Study on Trans-Neuronal Degeneration of the Thalamic Networks after Ischemic Stroke

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Thalamus 100%
  • Stroke 96%
  • Thalamic Nuclei 52%
  • Cerebral Infarction 43%
  • Gait 38%

• Mri Study on Trans-Neuronal Degeneration of the Thalamic Networks after Ischemic Stroke

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Thalamus 100%
  • Stroke 96%
  • Thalamic Nuclei 52%
  • Cerebral Infarction 43%
  • Gait 38%

• Moxibustion at Bl-25 Attenuated Stress-Sensitized Colon-Bladder Crosstalk by Thermal Effect Impacting Heat Shock Protein 90-Cochaperone Dynamics of Glucocorticoid Receptor

  Lin, T.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • HSP90 Heat-Shock Proteins 100%
  • Glucocorticoid Receptors 96%
  • Tacrolimus Binding Proteins 95%
  • Moxibustion 91%
  • Colon 52%

• Motorcycle Exhaust and Metabolic Activation

  Ueng, T.

  8/1/11 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • motorcycles 100%
  • toxicity 12%
  • cardiotoxicity 11%
  • trichloroethylene 7%
  • rats 6%

• Motion-Sensitive MR Imaging in Characterizing Brain Compliance in Cerebral Venous Hypertension: A Translational Study between Humans and Rats

  Lu, C., Liu, H., Chen, C. & Tsai, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Brain 100%
  • Cerebrospinal fluid 69%
  • Magnetic resonance 62%
  • Compliance 52%
  • Imaging techniques 46%

• Morin hydrate對血小板自噬作用以及對血小板活化過程中NF-κB調控路徑的影響

  Sheu, J.

  3/1/21 → 2/28/22

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• More healthy teas innovatively treated utilizing gold nanoparticles

  Liu, Y.

  1/1/13 → 12/31/13

  Project: C - Project of Alliance › j - National Taipei University of Technology

  • Polyphenol 100%
  • Nanoparticle 96%
  • Black 42%
  • Gold Nanoparticle 40%
  • Chitosan 39%

• Molecular Pathogenesis of Progression of Cerebral toxocariasis into Alzheimer’s-Like Disease Affected by Dysfunctional Regulation from Impaired UPS and ALS That Lead to Aberrant Βeta-Amyloid Generation and Metabolism in Brain

  Fan, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Toxocariasis 100%
  • Toxocara canis 75%
  • Proteasome Endopeptidase Complex 60%
  • Ubiquitin 51%
  • Amyloid Precursor Protein Secretases 45%

• Molecular Pathogenesis of Cerebral Neuroglia Cells on TJPs and Biabs Expressions as Well as UPS Dysfunction in Neurotoxocariasis That Develops Progressively into Alzheimer's-Like Diseases as Assessed by SP/NK-1R Inhibition

  Fan, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Substance P 100%
  • Tight Junction Proteins 89%
  • Toxocara canis 69%
  • Astrocytes 64%
  • Blood-Brain Barrier 56%

• Molecular Pathogenesis of Cerebral Neuroglia Cells on Tjps and Biabs Expressions as Well as Ups Dysfunction in Neurotoxocariasis That Develops Progressively into Alzheimer's-Like Diseases as Assessed by SP/NK-1R Inhibition

  Fan, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Substance P 100%
  • Tight Junction Proteins 74%
  • Toxocara canis 69%
  • Astrocytes 64%
  • Blood-Brain Barrier 56%

• Molecular Mechanism Underlying Progesterone-Regulated p27 Gene Expression

  Hsu, S.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • transcription (genetics) 100%
  • angiogenesis 82%
  • 5' untranslated regions 73%
  • promoter regions 72%
  • 3' untranslated regions 72%

• Molecular Mechanisms Underlying Statins-Suppressed Colorectal Cancer Progression: Role of P53 Family Proteins and Microrna

  Hsu, M.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 100%
  • Simvastatin 61%
  • Colorectal Neoplasms 49%
  • MicroRNAs 43%
  • Cell Death 31%

• Molecular Mechanisms of Secretory Rab Gtpase 3c in Promoting Colon Cancer Metastasis(3/3)

  Chen, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Mechanisms of Secretory Rab Gtpase 3c in Promoting Colon Cancer Metastasis(1/3)

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Mechanisms of Secretory Rab Gtpase 3c in Promoting Colon Cancer Metastasis

  Chen, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Mechanisms of Propofol-Involved Protection against Ischemia Brain Injuries 全文電子檔： 全文連結1

  Chen, T.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Propofol 100%
  • Ischemia 76%
  • Brain Injuries 75%
  • Reperfusion 34%
  • Mitogen-Activated Protein Kinases 30%

• Molecular Mechanisms of Propofol-Involved Protection against Ischemia Brain Injuries

  Chen, T.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Propofol 100%
  • Ischemia 76%
  • Brain Injuries 75%
  • Reperfusion 34%
  • Mitogen-Activated Protein Kinases 30%

• Molecular mechanisms of propofol-involved protection against ischemia brain injuries

  Chen, T.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Propofol 100%
  • Ischemia 76%
  • Brain Injuries 75%
  • Reperfusion 34%
  • Mitogen-Activated Protein Kinases 30%

• Molecular Mechanisms of PARP-1 in Regulating NLRP3 Inflammasome Activation

  Lin, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Poly (ADP-Ribose) Polymerase-1 100%
  • Inflammasomes 22%
  • Interleukin-1 15%
  • Poly ADP Ribosylation 9%
  • Caspase 1 7%

• Molecular Mechanisms of PARP-1 in Regulating NLRP3 Inflammasome Activation

  Lin, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Poly (ADP-Ribose) Polymerase-1 100%
  • Inflammasomes 22%
  • Interleukin-1 15%
  • Poly ADP Ribosylation 9%
  • Caspase 1 7%

• Molecular Mechanisms of Helicobacter Pylori Virulence Factors for Regulating Inflammation Responses in Epithelial Cells and Macrophages

  Lin, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Helicobacter pylori 100%
  • pylorus 80%
  • macrophages 74%
  • inducible nitric oxide synthase 44%
  • cholesterol 36%

• Molecular Mechanisms of Helicobacter Pylori Virulence Factors for Regulating Inflammation Responses in Epithelial Cells and Macrophages

  Lin, H.

  4/1/11 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Helicobacter pylori 100%
  • pylorus 80%
  • macrophages 74%
  • inducible nitric oxide synthase 44%
  • cholesterol 36%

• Molecular Mechanisms of C/EBP-Β Regulates microRNA-16 and Its Clinical Application(2/2)

  Chen, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Acute Kidney Injury 78%
  • Transcription Factors 68%
  • Reperfusion Injury 17%
  • Kidney 14%

• Molecular Mechanisms of C/EBP-Β Regulates microRNA-16 and Its Clinical Application

  Chen, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Acute Kidney Injury 78%
  • Transcription Factors 68%
  • Reperfusion Injury 17%
  • Kidney 14%

• Molecular Mechanisms of Anti-Inflammatory Effects of Intravenous Anesthetic Agent Ketamine on Lipopolysaccharide-Activated Macrophages

  Chen, T. & Chen, R.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • ketamine 100%
  • lipopolysaccharides 80%
  • macrophages 39%
  • Toll-like receptors 32%
  • cytokines 32%

• Molecular Mechanisms of Anti-Angiogenic Effects of 3-Methylcholanthrene, an Aryl-Hydrocarbon Receptor Agonist, in Relation to Cell Proliferation, Adhesion and Migration of Endothelial Cells, and Its Therapeutic Intervention Using Resveratrol

  Juan, S.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Methylcholanthrene 100%
  • Aryl Hydrocarbon Receptors 79%
  • Resveratrol 26%
  • Xenobiotics 24%
  • PTEN Phosphohydrolase 16%

• Molecular Mechanisms of a Novel Aliphatic Hydroxamate, WMJ-S-001, in Suppressing Colorectal Cancer Progression---The Causal Role of AMPK-p53 Modification-miRNAs Cascade

  Hsu, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • WMJ-S-001 100%
  • Neoplasms 11%
  • MicroRNAs 10%
  • Colorectal Neoplasms 7%
  • Lymphangiogenesis 6%

• Molecular Mechanisms of Alpha 9-Nicotinic Acetylcholine Receptor (Alpha 9-nAChRs)-Mediated Trastuzumab (Herceptin R) Drug Resistance in Breast Cancer Cells

  Ho, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Trastuzumab 79%
  • Liposomes 66%
  • MicroRNAs 56%
  • Nicotinic Receptors 49%

• Molecular Mechanisms of Alpha 9-Nicotinic Acetylcholine Receptor (Alpha 9-Nachr)-Mediated Trastuzumab (Herceptinr) Drug Resistance in Breast Cancer Cells

  Ho, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Liposomes 66%
  • MicroRNAs 56%
  • Trastuzumab 53%
  • Nicotinic Receptors 49%

• Molecular mechanisms of alpha9-nicotinic acetylcholine receptor (alpha 9-nAChR)-mediated Trastuzumab (HerceptinR) drug resistance in breast cancer cells

  Ho, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Liposomes 66%
  • MicroRNAs 56%
  • Trastuzumab 53%
  • Nicotinic Receptors 49%

• Molecular Mechanism of the Effect of Cafestol on Growth Factor-Induced Cardiomyocyte Hypertrophy

  Liu, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • cafestol 100%
  • Cardiac Myocytes 57%
  • urotensin II 55%
  • Hypertrophy 48%
  • Cardiomegaly 38%

• Molecular Mechanism in Amyloid Peptide-Induced Cerebral Endothelial Cell Apoptosis---Role of HDAC and AMPK

  Hsu, M.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylases 100%
  • Acetylation 90%
  • Endothelial Cells 54%
  • Cerebral Amyloid Angiopathy 51%
  • Sirtuins 49%

• Molecular Mechanism in Amyloid Peptide-Induced Cerebral Endothelial Cell Apoptosis:Role of Hdac and Ampk

  Hsu, M.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Acetylation 100%
  • Histone Deacetylases 95%
  • Endothelial Cells 60%
  • Cerebral Amyloid Angiopathy 57%
  • Sirtuins 55%

• Molecular Ivestigation of the Electron Transfer Flavoprotein Dehydrogenase Mutation Induced Mitochondrial Dysfunction and Metabolic Defects

  Kao, S. & Hsu, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • acyl-CoA dehydrogenase 100%
  • flavoproteins 97%
  • electron transfer 79%
  • droplets 39%
  • myoblasts 31%

• Molecular Insights into Ketogenic Diet on Cardiac Metabolic Disorders in Diabetic Cardiomyopathy

  Lee, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Immunopathogenesis of Dermatophagoides Pteronyssinus (Der P1) Allergen on the Progression of Pulmonary Toxocariasis-Causing Asthma and Fibrosis by Proteomic Approaches

  Fan, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Toxocariasis 100%
  • Toxocara canis 85%
  • Lung 52%
  • Ovum 50%
  • Asthma 44%

• Molecular Epidemiology of Urothelial Carcinoma Prognosis Based on Microrna Expression Profiles

  Wang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Carcinoma 87%
  • Biomarkers 34%
  • Neoplasms 34%
  • Arsenic 31%

• Molecular Epidemiology, Related Risk Factors and Phylogenetic Analysis of Epilepsy-Causing Neurotoxocariasis or Neurocysticercosis in the Kingdom of Eswatini, Africa

  Fan, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Epidemiological Study of Renal Cell Carcinoma---Arsenic Methylation Capability, 8-OHdG and Polymorphism of IRS and RAAS Exploration

  Hsueh, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Arsenic 100%
  • Renal Cell Carcinoma 62%
  • Methylation 54%
  • Insulin Receptor 26%
  • Enzymes 25%

• Molecular Epidemiological Study of Renal Cell Carcinoma - Arsenic Methylation Capability, 8OHdG and Polymorphism of IRS and RAAS Exploration

  Hsueh, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Arsenic 100%
  • Renal Cell Carcinoma 62%
  • Methylation 54%
  • Insulin Receptor 26%
  • Enzymes 25%

• Molecular Epidemiological Studies of Arsenical Skin Cancer: Effect of Gwas-Derived Snp Variants and Their Gene Expression on Cancer Risk

  Wu, M.

  8/1/18 → 7/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Skin Neoplasms 100%
  • Arsenic 97%
  • Single Nucleotide Polymorphism 31%
  • Methylation 26%
  • Neoplasms 24%