College of Medicine

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2026

• 3 Not started
• 282 Active
• 2721 Finished

Projects per year

Search results

• Finished

  Investigation of the Mechanism of Post-Fracture Immune Dysfunction and the Role of Statin in Its Prevention and Treatment Strategy: from Bench to Bedside

  Lin, J. A.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Wounds and Injuries 100%
  • MicroRNAs 80%
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 77%
  • 3' Untranslated Regions 65%
  • Immunosuppression 57%

• Study the Anti-Tumor Activity of E1A Gene Therapy---Focus on the Function and Biogenesis of microRNA

  Chen, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Neoplasms 27%
  • Breast Neoplasms 26%
  • Formal Social Control 14%
  • Genetic Therapy 12%

• TMU103-AE1-B34

  Tsai, P.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• The Effects and Molecular Mechanisms of Phthalates (DEHP 和DBP) on the Mitochondrial Function and Genetic Regulation in Ovarian Granulosa Cells and Mouse Embryo

  Tzeng, C. & Kao, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • phthalates 100%
  • granulosa cells 23%
  • reproductive system 17%
  • mice 14%
  • embryo (animal) 10%

• The Role of VEGF Isoform Change in Progressive Renal Fibrosis

  Chang, F.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Microvascular Rarefaction 100%
  • Vascular Endothelial Growth Factor A 96%
  • Kidney 93%
  • Pericytes 76%
  • Protein Isoforms 60%

• 探討Dicer在胰臟癌細胞對gemcitabine感受性的影響及其調控機制(1/3)

  Su, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Comparing the Inflammatory and Immunopathological Change of Brain in Hosts with Angiostrongylus Cantonensis Infection by Using nanoPET Imaging Technique

  Cheng, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Angiostrongyliasis 100%
  • Angiostrongylus cantonensis 97%
  • Positron-Emission Tomography 37%
  • Nuclear Medicine 34%
  • Brain 34%

• The Impact of Environmental Change on Spatial and Temporal Variations of Dengue Outbreaks---Toward Dengue Early Warning System

  Chuang, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Land use 100%
  • Population dynamics 81%
  • Alarm systems 62%
  • Remote sensing 57%
  • Satellites 42%

• An Investigation of the Combined Administration of Cholesterol-Lowering Agents and Anti-Diabetic Drugs on Cell Migration Inhibition of Anaplastic Thyroid Cancer Cells

  Hsu, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Anaplastic Thyroid Carcinoma 100%
  • Drug Combinations 32%
  • Troglitazone 22%
  • Lovastatin 20%
  • Neoplasms 12%

• Gene Knock out Mice Model for Studying the Molecular Mechanisms of Early Onset Breast Tumor Microenvironment Regulation.

  Wu, C., Ho, Y. & Tu, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • breast 100%
  • cancer 97%
  • tumors 59%
  • fibroblasts 33%
  • genes 31%

• Genomic, Epigenomic and Epiproteomic Analysis of Etk/Bmx Traumatic Brain Injury

  Chen, K., Chiang, Y. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Protein Kinases 15%
  • Epigenomics 14%
  • Tec protein-tyrosine kinase 14%
  • Inflammation Mediators 10%

• Application of Data Mining Techniques for National Health Insurance Research Database Analysis to Develop Risk Assessment System of Major Postoperative Complications

  Lin, C., Liao, C. & Chiu, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Asthma 100%
  • Postoperative Complications 77%
  • Odds Ratio 41%
  • National Health Programs 27%
  • Mortality 25%

• TMU103-AE1-B29

  Liu, H.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• The Measure of Palliative Care Spiritual Care Competency and the Effectiveness of an Educational Program for Palliative Spiritual Care Providers

  Chiou, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Palliative Care 100%
  • Program Evaluation 46%
  • Education 32%
  • Research Design 24%
  • Learning 15%

• An Action Research Approach to Clinical Skills Education Development : Using Reflective Writing to Promote the Transformation of Students’ Skill Acquisition toward the Way of Better-Best-Practice

  Lin, W., Chen, C. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • action research 100%
  • instruction 69%
  • medicine 54%
  • development project 36%
  • reflexivity 35%

• TMU103-AE1-B35

  Huang, T.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Molecular Ivestigation of the Electron Transfer Flavoprotein Dehydrogenase Mutation Induced Mitochondrial Dysfunction and Metabolic Defects

  Kao, S. & Hsu, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • acyl-CoA dehydrogenase 100%
  • flavoproteins 97%
  • electron transfer 79%
  • droplets 39%
  • myoblasts 31%

• An Action Research Placing Taiwan as Asia Medical Professionalism Leadership through International and Cross-Generational Partnership: Proposing Medical Visions Based upon Doing Bioethics

  Tsai, D.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • bioethics 100%
  • electronic learning 89%
  • professionalism 72%
  • Taiwan 50%
  • moral philosophy 33%

• Short-Chain Fatty Acids Act as Anti-Allergic Regulators on Immune Effector Cells and Exert Immune-Modulatory Effects on Ovalbumin-Induced Allergic Diseases in Mice

  Lee, Y. & Hsiao, G.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Volatile Fatty Acids 100%
  • Phenylbutyrates 27%
  • Mast Cells 25%
  • Immunoglobulin E 19%
  • Asthma 16%

• Investigating a Novel Cancer Stem Cell Biomarker Podocalyxin-Like Protein 1 Promotes Epithelial-Mesenchymal Transition and Cancer Stemness in Breast Cancer Cells

  Lin, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • podocalyxin 100%
  • Neoplastic Stem Cells 43%
  • Epithelial-Mesenchymal Transition 26%
  • Proteins 24%
  • Breast Neoplasms 22%

• A Wearable Device Evaluation for Medication Management in Patients Taking Sleep Medicine via Cloud Platform Development( I )

  Li, Y., Jian, W. & Lee, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sleep 100%
  • Wearable technology 35%
  • Health 28%
  • Education 19%
  • Oximeters 11%

• The Role of CD24 in TNF-Alpha-Inhibited Erythroid Differentiation and Its Signaling Pathway

  Huang, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • activin A 100%
  • Tumor Necrosis Factor-alpha 96%
  • Globins 56%
  • Hematopoietic Stem Cells 53%
  • K562 Cells 53%

• Characterization of 5-Hydroxymethylcytosine and Ten-to-Eleven Translocation Gene (TET) in Cervical Cancer

  Lai, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 5-hydroxymethylcytosine 100%
  • Uterine Cervical Neoplasms 38%
  • Epigenomics 20%
  • 5-Methylcytosine 17%
  • Carcinogenesis 9%

• Kidney Injury and Heat Shock Protein Modulate the Atrial Electrophysiological Characterisitcs

  Hsieh, M., Chen, Y. & Lin, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Renal Insufficiency 100%
  • Atrial Fibrillation 87%
  • Heat-Shock Proteins 68%
  • Indican 66%
  • Neomycin 41%

• Roles of Central OX2R Activities in the Pathophysiology of Hypertension in SHR

  Hwang, L.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Orexin Receptors 100%
  • Paraventricular Hypothalamic Nucleus 54%
  • Inbred SHR Rats 50%
  • Hypertension 43%
  • Neurons 34%

• Study of Expression and Functional Mechanisms of Histone 3 K4 Demethylase JARID1B in Tumorigenesis and Correlation with Progression in Lung Cancer

  Kuo, K., Wang, L. & Yeh, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lung Neoplasms 100%
  • Histones 46%
  • Carcinogenesis 42%
  • Neoplasms 24%
  • Genes 22%

• ALA Photodynamic Therapy, Tumor Hypoxia, CSE1L Phosphorylation, and the Progression and Treatment of Skin Cancer

  Lee, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Skin Neoplasms 100%
  • Aminolevulinic Acid 31%
  • Tumor Hypoxia 25%
  • Neoplasms 24%
  • Photochemotherapy 20%

• The Role of Inflammatory Gene Polymorphisms on Risk of Post-Stroke Vascular Dementia (I)

  Chiou, H., Chi, N., Lin, H., Wu, C., Hsieh, F., Hu, C. & Hsieh, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 93%
  • Cognitive Dysfunction 89%
  • Blood Vessels 52%
  • Inflammation 36%
  • Whole Exome Sequencing 16%

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C. & Ho, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Trastuzumab 88%
  • Neoplastic Stem Cells 39%
  • Drug Resistance 27%
  • Luciferases 20%

• Characterizing the Therapeutic Roles of Depleting Brain-Infiltrated Leukocytes Using Pan-Selectin Antagonist and Intravenous Immunoglobulins in Traumatic Brain Injury

  Chang, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • uproleselan sodium 100%
  • Traumatic Brain Injury 71%
  • Intravenous Immunoglobulins 67%
  • Leukocytes 42%
  • Selectins 31%

• The Study of Therapeutic Effects for Stroke with Phenserine, an Amyloid Precursor Protein Inhibitor, in Rodent Focal Cerebral Ischemia Model

  Chang, C. & Chiang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • phenserine 100%
  • Stroke 75%
  • Amyloid beta-Protein Precursor 49%
  • pifithrin 40%
  • Stem Cells 31%

• Pitx2c Modulations on Atrial Fibroblast Activity, Electrical Characteristic, and Myocyte-Fibroblast Interaction: Implications in the Genesis of Atrial Fibrillation

  Kao, Y. & Chen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibroblasts 100%
  • Atrial Fibrillation 36%
  • Electrophysiology 26%
  • Angiotensin II 22%
  • Cardiac Myocytes 21%

• Identification of Roles of microRNAs in Drug Resistance Development of Chronic Myeloid Leukemia

  Shih, C. & Liu, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 87%
  • Drug Resistance 40%
  • Imatinib Mesylate 29%
  • ran GTP-Binding Protein 29%

• Contribution of ER Stress to Inhibit miR-19a/b and miR-26b-Mediated CTGF Expression in Lung Fibrosis (III)

  Chen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Traumatic Brain Injury Triggers Acute Lung Injury---The Priming Effects Underlying Subsequent Neurological Sequelae and Cross Organ Injuries

  Wang, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Acute Lung Injury 69%
  • Adult Respiratory Distress Syndrome 16%
  • Brain Injuries 9%
  • Chemokines 9%

• Studies on the Role of ORMDL3 in Thrombin-Induced IL-8/CXCL8 Expression and Airway Inflammation

  Chen, B.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Orosomucoid 100%
  • Thrombin 74%
  • Interleukin-8 34%
  • Transcription Factor AP-1 26%
  • Asthma 23%

• Copy Number Alterations and Transcriptome Profile Analyses Reveal Genetic Determinants Contributing to Higher Paclitaxel-Resistance of Ovarian Clear Cell Adenocarcinoma

  Chang, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Clear Cell Adenocarcinoma 100%
  • Paclitaxel 91%
  • Transcriptome 22%
  • Cell Movement 20%
  • Signal Transduction 19%

• TMU103-AE1-B28

  Chiu, H.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Whole Organ Decellularizationtrachea Scaffold Tissue Engineering for Whole Segment Tracheal Transplantation/Replacement

  Hung, S., Lee, F. & Tseng, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • trachea (vertebrates) 100%
  • cartilage 77%
  • sonication 70%
  • tissues 27%
  • skeleton 25%

• Anti-Aging Effect with the Associated Mechanism by PRP (Platelet-Rich Plasma) in Cartilage---A Fibronectin Fragment Model

  Lee, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fibronectins 100%
  • cartilage 63%
  • Toll-like receptor 2 58%
  • osteoarthritis 50%
  • chondrocytes 42%

• Roles of calcium channel in ER(先期補助)

  Wu, M.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• SOX2-Mediated Oncogenesis and Its Crosstalk with Environmental Risk Factors in Bladder Cancer

  Wang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Urinary Bladder Neoplasms 100%
  • Arsenic 24%
  • Stem Cells 23%
  • Neoplastic Stem Cells 22%
  • Cigarette Smoking 20%

• To Identify Whether Ion Conductance Dysfunction Is an Early Electrophsiological Biomarker of Polyneuropathy in Diabetic Patients: a Longitudinal Study of Nerve Excitability in Diabetic Patients

  Sung, J. & Hu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neural Conduction 100%
  • Diabetic Neuropathies 69%
  • Ions 24%
  • Biomarkers 19%
  • Polyneuropathies 17%

• Study on the Mechanism Involved in Nanoparticles-Induced Tight Junction and Aquaporins Damages in Endothelial Cells, as Well as the Effects on Physiological Function of Endothelial Barriers

  Li, C. & Cheng, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Nanoparticles 100%
  • Blood-Brain Barrier 69%
  • Aquaporins 65%
  • Tight Junction Proteins 39%
  • Permeability 35%

• Lipid Raft Associated Signaling in Regulation of Osteoclast Activation in Inflammatory Arthritis

  Tsai, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Osteoclasts 100%
  • Arthritis 34%
  • Osteogenesis 33%
  • Lipids 31%
  • Inflammation 28%

• To Investigate the Role of SPNS2 in Determining Individual Susceptibility to Hypoxic Challenge

  Yang, C. H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phenotype 100%
  • Pharmacology 55%
  • Physiological Adaptation 54%
  • Middle Cerebral Artery Infarction 45%
  • Neurodegenerative Diseases 36%

• The Comparison of Complications and Mortality after Surgery between General Anesthesia and Regional Anesthesia in the Elderly

  Liao, C., Cherng, Y. & Chen, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Conduction Anesthesia 100%
  • General Anesthesia 89%
  • Elderly 42%
  • Mortality 35%
  • Postoperative Complications 30%

• An Investigation of the Effects of Tea Component on the Inhibition of Leukocyte Nicotinic Acetylcholine Receptor Expression on Breast Cancer Patients

  Tu, S. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Leukocytes 100%
  • Tea 92%
  • Breast Neoplasms 87%
  • Nicotine 31%
  • Capsules 28%

• Bone-Marrow-Derived Mesenchymal Stem Cells in Prostate Cancer-Induced Bone Remodeling

  Hsieh, C., Chen, K. & Sung, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adipogenic 100%
  • Osteogenic 37%

• Development of a Computerized Adaptive Testing of the Health Literacy in Stroke Rehabilitation.

  Hou, W. & Chen, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Health Literacy 100%
  • Stroke Rehabilitation 86%
  • Psychometrics 23%
  • Stroke 21%
  • Rehabilitation 19%