College of Medicine

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 2 Not started
• 229 Active
• 3026 Finished

Projects per year

Search results

• A Study of Diffusion Tensor Imaging as a Potential Surrogate Marker for the Management of Acute Ischemic Cerebral Stroke: a Clinical and Animal Model at 7t

  Chen, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Anisotropy 100%
  • Diffusion Tensor Imaging 36%
  • Stroke 32%
  • Animal Models 28%
  • Magnetic Resonance Imaging 21%

• Circuits of Igf-1r and Niche Signaling (Hypoxia/Inflammation) in Stem Cell Transformation and Its Clinical Implication of Molecular Target Therapy (Model of Germline Stem Cells)

  Huang, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplastic Stem Cells 100%
  • Stem Cells 86%
  • Hypoxia 55%
  • Inflammation 34%
  • Seminoma 29%

• Therapeutic Strategies for Traumatic Brain Injury with Novelly Desinged Drugs( I )

  Wang, J.

  8/1/12 → 7/31/14

  Project: B - Project of TMU › i - Other (Funded by TMU)

  • Traumatic Brain Injury 100%
  • Research Personnel 51%
  • Pharmaceutical Preparations 22%
  • Touch 18%
  • MicroRNAs 15%

• The Influence of Porphyromonas Gingivalis Groel in Vascular Cells

  Lin, F.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Porphyromonas gingivalis 100%
  • blood vessels 46%
  • myocytes 40%
  • smooth muscle 39%
  • atherosclerosis 36%

• Functional Role of Transcription Factor Sp1 in Brain Neuronal Injury( I )

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Brain Injuries 100%
  • sigma Receptors 51%
  • Internal Ribosome Entry Sites 24%
  • Genes 20%
  • Animal Models 18%

• Translational Genomic Approaches in Endometriosis

  Tzeng, C.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • endometrium 100%
  • microRNA 90%
  • stem cells 61%
  • cell adhesion molecules 54%
  • metastasis 35%

• Endothelin-1 Mediates Fibrocyte Differentiation in Chronic Obstructive Asthma

  Lin, C.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Asthma 100%
  • Fibrosis 76%
  • Myofibroblasts 73%
  • Lung 61%
  • Connective Tissue Growth Factor 51%

• The Study of the Involvement of Micrornas in Pressure-Induced Initial Renal Fibrosis

  Chen, T.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibrosis 100%
  • MicroRNAs 73%
  • Pressure 56%
  • Kidney 55%
  • Chronic Renal Insufficiency 29%

• The Neurotrophic/Neuroprotective Role of Gip in Cellular and Rodent Models of Mild Traumatic Brain Injury.( I )

  Lin, J. & Chen, R.

  8/1/12 → 7/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

  • Peptides 62%
  • Glucose 62%
  • Incretins 25%
  • Glucagon-Like Peptide 1 23%
  • Neuroprotection 20%

• Modulation of Tumor Microenvironment by Nucleic Acid Chimeras as a New Paradigm for Adjuvant Cancer Therapy

  Yeh, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • neoplasms 100%
  • cytokines 66%
  • neoplasm progression 60%
  • neoplasm cells 55%
  • chimerism 45%

• NF-kB以及NF-kB repressing factor (NRF) 在慢性阻塞性肺疾病引發系統性發炎之角色探討(3/3)

  Lee, K.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Er Stress in Evodiamine-Induced Apoptosis and G2/M Arrest of Human Colorectal Carcinoma Cells

  Chen, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colorectal Neoplasms 100%
  • Apoptosis 41%
  • Cyclin B1 30%
  • Proteins 16%
  • HT29 Cells 14%

• The Influences and Underlying Mechanisms of Differentiation and Proliferation in Ox-Ldl and Hdl-Stimulated Human Late-Outgrowth Endothelial Progenitor Cells

  Huang, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Endothelial Progenitor Cells 100%
  • erucylphosphocholine 98%
  • Endothelium 28%
  • HDL Lipoproteins 25%
  • Dyslipidemias 23%

• 榖胱甘月太硫轉移酉每參與乳癌致癌之分子機制探討(1/3)

  Wu, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular and Cellular Mechanism of Adipocyte Modulatory Effects on Pulmonary Vein and Atrium

  Chen, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adipocytes 100%
  • Atrial Fibrillation 64%
  • Cardiac Myocytes 60%
  • Calcium 44%
  • Adipokines 37%

• Oxidative Stress and Bisphenol a Impact on the Women with Polycystic Ovary Syndrome

  Hsu, M.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • oxidative stress 100%
  • woman 65%
  • reactive oxygen species 61%
  • disturbance 47%
  • gamete 45%

• Studies of Molecular and Cellular Underlying Mechanisms of Ferrous Citrate-Induced Cerebral Vasospasm and Brain Injury

  Lee, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Subarachnoid Hemorrhage 100%
  • monoferrous acid citrate 89%
  • Intracranial Vasospasm 74%
  • Brain Injuries 53%
  • Thioredoxins 49%

• Reconstitution of Spermatogenesis from Testis Failure after Spermatogonial Stem Cells (Ssc) Transplantation for Male Fertility Preservation-A Transgenic Mouse Model

  Chen, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • stem cells 100%
  • stems 51%
  • cryopreservation 37%
  • germ cells 26%
  • mice 21%

• Application of Functional Electrical Stimulation on the Study of Nerve Regeneration in the Rat with Diabetic Neuropathy

  Peng, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electric Stimulation 100%
  • Nerve Regeneration 94%
  • Urinary Tract 93%
  • Diabetes Mellitus 49%
  • Nerve Fibers 45%

• Roles of Toll-Like Receptor-4 and Hif-1 in Propofol-Involved Protection against Traumatic Brain Injury-Induced Dysfunction of the Blood-Brain Barrier

  Chang, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Blood-Brain Barrier 100%
  • Propofol 73%
  • Hypoxia 63%
  • Brain Edema 25%
  • Craniocerebral Trauma 22%

• Studies of Cxcl12 in Hypoxia-Induced Pulmonary Fibrosis

  Chen, B.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hypoxia 100%
  • Pulmonary Fibrosis 62%
  • Fibroblasts 58%
  • Lung 55%
  • Phosphatidylinositol 3-Kinases 35%

• 抑制SP/NK-1R的表現探討腦部神經膠質細胞對血腦屏蔽緊密連結蛋白與腦部損傷相關生物標記的表現和泛素蛋白#37238

  Fan, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Cd69 in Tnfalpha-Inhibited Erythroid Differentiation

  Huang, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Tumor Necrosis Factor-alpha 100%
  • Erythropoietin 95%
  • Anemia 33%
  • Hematopoietic Stem Cells 29%
  • Inflammation 29%

• Study the Role of the Endoplasmic Reticulum Stress Related Proteins, Glycoprotein 96(Gp96), in Liver Cancer Progression and Metastasis and the Clinically Therapeutic Implication

  Huang, M.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycoproteins 100%
  • Heat-Shock Proteins 36%
  • Endoplasmic Reticulum Stress 26%
  • Liver Neoplasms 23%
  • Neoplasm Metastasis 21%

• Study on the Immuno-Modulatory Effects of Notch Ligand Delta 4 on Immune Cells and in Ova-Induced Asthmatic Mice

  Lee, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Dendritic Cells 100%
  • Ligands 43%
  • Asthma 39%
  • STAT4 Transcription Factor 34%
  • Th2 Cells 23%

• Cytotoxicity and Application on Drug Resistant Cells of Halide Derivatives of Rutaecarpine

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Evodiamine 100%
  • Poison 67%
  • Halide 66%
  • Topoisomerase Inhibitor 49%
  • Antimicrobial Agent 40%

• The Relationship between Sleep and Memory in Alzheimer Animal

  Hu, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Alzheimer Disease 100%
  • Memory Consolidation 93%
  • REM Sleep 91%
  • Sleep 85%
  • Dementia 30%

• Roles of Central Orexin Activities in the Pathophysiology of Hypertension in Shr

  Hwang, L.

  8/1/12 → 9/30/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Orexins 100%
  • Orexin Receptors 97%
  • Inbred SHR Rats 57%
  • Hypertension 30%
  • Arterial Pressure 23%

• Genomic and Non-Genomic Estrogen Effects on the Spinal Nr2b-Related Uterus-Colon Crosstalk in Rats

  Lin, T.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • uterus 100%
  • colon 95%
  • estrogens 62%
  • irritable bowel syndrome 33%
  • comorbidity 31%

• The Neurotrophic/Neuroprotective Role of Gip in Cellular and Rodent Models of Mild Traumatic Brain Injury.( I )

  Lin, J.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Peptides 62%
  • Glucose 62%
  • Incretins 25%
  • Glucagon-Like Peptide 1 23%
  • Neuroprotection 20%

• The Role of Hypoxia in Transcriptomics and Epigenomics Regulation during Pre-Implantation Embryo Development

  Tzeng, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • hypoxia 100%
  • embryogenesis 74%
  • epigenetics 57%
  • microRNA 22%
  • embryo implantation 18%

• Epigenetic Regulation of Lps-Induced G-Csf Expression in Macrophages

  Chang, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Granulocyte Colony-Stimulating Factor 100%
  • Macrophages 19%
  • Epigenomics 17%
  • MicroRNAs 13%
  • Inflammation 11%

• Pulmonary Effects of Chorioamnionitis and Postnatal Hyperoxia in Rat Offspring

  Chen, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chorioamnionitis 100%
  • Hyperoxia 72%
  • Bronchopulmonary Dysplasia 58%
  • Renin-Angiotensin System 48%
  • Lung Injury 37%

• Novel Roles of Arnt in Breast Tumor Progression, Metastasis and Therapy

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epidermal Growth Factor 100%
  • Neoplasms 65%
  • Arachidonate 12-Lipoxygenase 45%
  • Neoplasm Metastasis 45%
  • Xenobiotics 32%

• Analysis the Role of Satellite Cell during Denervation Induced Muscular Atrophy and a Trail of Transplantation of Adipocyte Derived Myogenic Stem Cells.

  Chang, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Denervation 100%
  • Atrophy 63%
  • Myogenic Regulatory Factors 33%
  • Muscular Atrophy 23%
  • Adipocytes 19%

• The Roles of Fibronectin Fragments in the Articular Chondrocytes: from Single Nucleotide Polymorphism to Functional Investigation.

  Lee, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fibronectins 100%
  • chondrocytes 59%
  • cartilage 53%
  • integrins 43%
  • osteoarthritis 23%

• Role of Sp-Family in Lung Tumorigenesis

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lung 100%
  • Lung Neoplasms 73%
  • Carcinogenesis 61%
  • Doxycycline 61%
  • Neoplasms 43%

• Studies on the Carcinogenic Mechanisms of Histamine N-Methyltransferase-Mediated Breast Cancer Formation

  Wu, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Breast Neoplasms 19%
  • Neoplasms 7%
  • Carcinogenesis 6%

• A Study on Trans-Neuronal Striato-Nigral Degeneration-Induced Movement Disorders after Stroke: Evaluation with Grey Matter Suppression Ir and Diffusion Tensor Imaging( I )

  Chen, C.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Movement Disorders 100%
  • Stroke 53%
  • Diffusion Tensor Imaging 50%
  • Middle Cerebral Artery 48%
  • Gray Matter 45%

• Dissected the Role of Alpha-7 Nicotinic Receptor in the Prognosis and Clinical Therapy on Gastric Cancers

  Chang, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stomach Neoplasms 100%
  • Nicotinic Receptors 76%
  • Nicotine 45%
  • alpha7 Nicotinic Acetylcholine Receptor 19%
  • Therapeutics 18%

• The Effects of Atherosclerosis Progression in Circulating Ferritin in Community-Based Population

  Bai, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • blood samples 100%
  • blood pressure 88%
  • cardiovascular disease 88%
  • chronic illness 69%
  • examination 40%

• Investigation on Developing Novel Biomarkers and Treatments in the Patients with Fibromyalgia

  Kang, J.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibromyalgia 100%
  • Transcranial Direct Current Stimulation 38%
  • Exercise 32%
  • Virtual Reality 30%
  • Biomarkers 12%

• Mechanisms of Apelin in Electrophysiological Characteristics and Calcium Dynamics in Left Atrium and Pulmonary Vein Cardiomyocytes Underlying the Pathophysiology of Atrial Fibrillation

  Chen, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Apelin 100%
  • Pulmonary Veins 51%
  • Cardiac Myocytes 39%
  • Atrial Fibrillation 27%
  • Calcium 13%

• Investigation of the Transcriptional and Epigenetic Mechanisms for the Nm23-H1 Expression: an Nm23-H1-Promoter Screening Platform for Novel Metastasis-Suppressing Anticancer Drugs

  Wang, L.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplasm Metastasis 100%
  • Genetic Promoter Regions 93%
  • Methylation 87%
  • Esophageal Neoplasms 66%
  • Tumor Suppressor Genes 63%

• Trajectories, Predictors of Return-to-Work, and the Impact of Return-to-Work in Predicting the Quality-of-Life among Workers with Traumatic Limb Injuries

  Hou, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • worker 100%
  • quality of life 72%
  • rehabilitation 37%
  • hospital admission 32%
  • International Classification 29%

• Roles of Autophagy and Heme Oxygenases(-1, -2) in Brain Injuries: in Vivo and in Vitro Studies

  Wang, J.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Autophagy 97%
  • Brain Injuries 62%
  • heme oxygenase-2 59%
  • Reperfusion 56%

• Therapeutic Strategies for Traumatic Brain Injury with Novelly Desinged Drugs( I )

  Wang, J.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Research Personnel 51%
  • Pharmaceutical Preparations 22%
  • Touch 18%
  • MicroRNAs 15%

• Macro and Micro Biomechanical Studies of Soft Tissue Remodeling under Tissue Expansion (II)

  Chen, H.

  8/1/12 → 1/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tissues 100%
  • mechanical properties 29%
  • animal injuries 22%
  • clinical trials 21%
  • texture 16%

• Novel Activities of Gamma-Aminobutyric Acid-Mediated Regulation of Platelet Activation, Apoptosis, and Autophagy: the Non-Genomic Functions of Nf-Kappab Signal in Anucleated Cells

  Sheu, J.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • gamma-Aminobutyric Acid 100%
  • Blood Platelets 65%
  • Platelet Activation 27%
  • Mitochondrial DNA 26%
  • Autophagy 20%

• Effect of Pacemaker Current Inhibitor (Ivabradine) on Sinoatrial Node Function and Pulmonary Vein Arrhythmogenesis

  Lin, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pulmonary Veins 100%
  • Ivabradine 66%
  • Atrial Fibrillation 48%
  • Sinoatrial Node 40%
  • Cardiac Arrhythmias 27%