College of Medical Science and Technology

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output

2020

Alzheimer’s Disease and Diabetes: Insulin Signaling as the Bridge Linking Two Pathologies

Shieh, J. C. C., Huang, P. T. & Lin, Y. F., Jan 1 2020, (Accepted/In press) In : Molecular Neurobiology.

Research output: Contribution to journalReview article

Application of a Common Data Model (CDM) to rank the paediatric user and prescription prevalence of 15 different drug classes in South Korea, Hong Kong, Taiwan, Japan and Australia: An observational, descriptive study

Brauer, R., Wong, I. C. K., Man, K. K. C., Pratt, N. L., Park, R. W., Cho, S. Y., Li, Y. C., Iqbal, U., Nguyen, P. A. A. & Schuemie, M., Jan 13 2020, In : BMJ Open. 10, 1, p. e032426 032426.

Research output: Contribution to journalArticle

Open Access

AR ubiquitination induced by the curcumin analog suppresses growth of temozolomide-resistant glioblastoma through disrupting GPX4-Mediated redox homeostasis

Chen, T. C., Chuang, J. Y., Ko, C. Y., Kao, T. J., Yang, P. Y., Yu, C. H., Liu, M. S., Hu, S. L., Tsai, Y. T., Chan, H., Chang, W. C. & Hsu, T. I., Feb 1 2020, In : Redox Biology. 30, p. 101413 101413.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Clinical trials of new drugs for Alzheimer disease

Huang, L. K., Chao, S. P. & Hu, C. J., Jan 6 2020, In : Journal of Biomedical Science. 27, 1, 18.

Research output: Contribution to journalReview article

Open Access
Open Access
Open Access

Development of nanosome-encapsulated honokiol for intravenous therapy against experimental autoimmune encephalomyelitis

Hsiao, Y. P., Chen, H. T., Liang, Y. C., Wang, T. E., Huang, K. H., Hsu, C. C., Liang, H. J., Huang, C. H. & Jan, T. R., Jan 1 2020, In : International Journal of Nanomedicine. 15, p. 17-29 13 p.

Research output: Contribution to journalArticle

Open Access

Early transcranial direct current stimulation treatment exerts neuroprotective effects on 6-OHDA-induced Parkinsonism in rats

Feng, X. J., Huang, Y. T., Huang, Y. Z., Kuo, C. W., Peng, C. W., Rotenberg, A., Juan, C. H., Pei, Y. C., Chen, Y. H., Chen, K. Y., Chiang, Y. H., Liu, H. H., Wu, J. X. & Hsieh, T. H., May 1 2020, In : Brain Stimulation. 13, 3, p. 655-663 9 p.

Research output: Contribution to journalArticle

Open Access

Efficient labeling of mesenchymal stem cells for high sensitivity long-term MRI monitoring in live mice brains

Ahmed Ali, A. A., Shahror, R. A. & Chen, K. Y., Jan 1 2020, In : International Journal of Nanomedicine. 15, p. 97-114 18 p.

Research output: Contribution to journalArticle

Open Access
Open Access

Evaluation of machine learning methods to stroke outcome prediction using a nationwide disease registry

Lin, C. H., Hsu, K. C., Johnson, K. R., Fann, Y. C., Tsai, C. H., Sun, Y., Lien, L. M., Chang, W. L., Chen, P. L., Lin, C. L. & Hsu, C. Y., Jul 2020, In : Computer Methods and Programs in Biomedicine. 190, 105381.

Research output: Contribution to journalArticle

Open Access

Focal TLR4 activation mediates disturbed flow-induced endothelial inflammation

Qu, D., Wang, L., Huo, M., Song, W., Lau, C. W., Xu, J., Xu, A., Yao, X., Chiu, J. J., Tian, X. Y. & Huang, Y., Jan 1 2020, In : Cardiovascular Research. 116, 1, p. 226-236 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Inhibition of alternative cancer cell metabolism of egfr mutated non-small cell lung cancer serves as a potential therapeutic strategy

Huang, C. Y., Hsu, L. H., Chen, C. Y., Chang, G. C., Chang, H. W., Hung, Y. M., Liu, K. J. & Kao, S. H., Jan 2020, In : Cancers. 12, 1, 181.

Research output: Contribution to journalArticle

Open Access

Inhibition of miR-21 alleviated cardiac perivascular fibrosis via repressing EndMT in T1DM

Li, Q., Yao, Y., Shi, S., Zhou, M., Zhou, Y., Wang, M., Chiu, J. J., Huang, Z., Zhang, W., Liu, M., Wang, Q. & Tu, X., Jan 1 2020, In : Journal of Cellular and Molecular Medicine. 24, 1, p. 910-920 11 p.

Research output: Contribution to journalArticle

Open Access

Knockdown of serine/threonine-protein kinase 24 promotes tumorigenesis and myeloid-derived suppressor cell expansion in an orthotopic immunocompetent gastric cancer animal model

Hsu, H. P., Wang, C. Y., Hsieh, P. Y., Fang, J. H. & Chen, Y. L., Jan 1 2020, In : Journal of Cancer. 11, 1, p. 213-228 16 p.

Research output: Contribution to journalArticle

Open Access

Long-term Proton Pump Inhibitor Administration Caused Physiological and Microbiota Changes in Rats

Yang, Y. C. S. H., Chang, H. W., Lin, I. H., Chien, L. N., Wu, M. J., Liu, Y. R., Chu, P. G., Xie, G., Dong, F., Jia, W., Chang, V. H. S. & Yen, Y., Dec 1 2020, In : Scientific Reports. 10, 1, 866.

Research output: Contribution to journalArticle

Open Access

Macrophages protect mycoplasma-infected chronic myeloid leukemia cells from natural killer cell killing

Choo, Q. W. W., Koean, R. A. G., Chang, S. C., Chng, W. J., Chan, M. C., Wang, W., Er, J. Z. & Ding, J. L., Feb 1 2020, In : Immunology and Cell Biology. 98, 2, p. 138-151 14 p.

Research output: Contribution to journalArticle

Open Access

Melatonin activates cell death programs for the suppression of uterine leiomyoma cell proliferation

Lin, P. H., Tung, Y. T., Chen, H. Y., Chiang, Y. F., Hong, H. C., Huang, K. C., Hsu, S. P., Huang, T. C. & Hsia, S. M., Jan 1 2020, In : Journal of Pineal Research. 68, 1, p. e12620 e12620.

Research output: Contribution to journalArticle

1 Citation (Scopus)

N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression

Mehndiratta, S., Lin, M. H., Wu, Y. W., Chen, C. H., Wu, T. Y., Chuang, K. H., Chao, M. W., Chen, Y. Y., Pan, S. L., Chen, M. C. & Liou, J. P., Jan 1 2020, In : European Journal of Medicinal Chemistry. 185, p. 111725 111725.

Research output: Contribution to journalArticle

1 Citation (Scopus)

NDAT suppresses pro-inflammatory gene expression to enhance resveratrol-induced anti-proliferation in oral cancer cells

Ho, Y., Wu, C. Y., Chin, Y. T., Li, Z. L., Pan, Y. S., Huang, T. Y., Su, P. Y., Lee, S. Y., Crawford, D. R., Su, K. W., Chiu, H. C., Shih, Y. J., Changou, C. A., Yang, Y. C. S. H., Whang-Peng, J., Chen, Y. R., Lin, H. Y., Mousa, S. A., Davis, P. J. & Wang, K., Feb 1 2020, In : Food and Chemical Toxicology. 136, p. 111092 111092.

Research output: Contribution to journalArticle

Obesity is less frequently associated with cognitive impairment in elderly individuals: A cross-sectional study in Yogyakarta, Indonesia

Vidyanti, A. N., Hardhantyo, M., Wiratama, B. S., Prodjohardjono, A. & Hu, C. J., Feb 2020, In : Nutrients. 12, 2, 367.

Research output: Contribution to journalArticle

Open Access

Ovatodiolide suppresses oral cancer malignancy by down-regulating exosomal mir-21/STAT3/β-catenin cargo and preventing oncogenic transformation of normal gingival fibroblasts

Chen, J. H., Wu, A. T. H., Bamodu, O. A., Yadav, V. K., Chao, T. Y., Tzeng, Y. M., Mukhopadhyay, D., Hsiao, M. & Lee, J. C., Jan 2020, In : Cancers. 12, 1, 56.

Research output: Contribution to journalArticle

Open Access

Pilot Study to Establish a Novel Five-Gene Biomarker Panel for Predicting Lymph Node Metastasis in Patients With Early Stage Endometrial Cancer

Huang, C. Y., Liao, K. W., Chou, C. H., Shrestha, S., Yang, C. D., Chiew, M. Y., Huang, H. T., Hong, H. C., Huang, S. H., Chang, T. H. & Huang, H. D., Jan 21 2020, In : Frontiers in Oncology. 9, 1508.

Research output: Contribution to journalArticle

Open Access

Predicting Lung Cancer Occurrence in Never-Smoking Females in Asia: TNSF-SQ, a Prediction Model

Chien, L. H., Chen, C. H., Chen, T. Y., Chang, G. C., Tsai, Y. H., Hsiao, C. F., Chen, K. Y., Su, W. C., Wang, W. C., Huang, M. S., Chen, Y. M., Chen, C. Y., Liang, S. K., Chen, C. Y., Wang, C. L., Lee, M. H., Chung, R. H., Tsai, F. Y., Hu, J. W., Katki, H. A. & 8 others, Chatterjee, N., Chanock, S. J., Rothman, N., Lan, Q., Yang, P. C., Chen, C. J., Chang, I. S. & Hsiung, C. A., Feb 1 2020, In : Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 29, 2, p. 452-459 8 p.

Research output: Contribution to journalArticle

Open Access

Quantitative analysis of melanosis coli colonic mucosa using textural patterns

Lo, C. M., Chen, C. C., Yeh, Y. H., Chang, C. C. & Yeh, H. J., Jan 1 2020, In : Applied Sciences (Switzerland). 10, 1, 404.

Research output: Contribution to journalArticle

Open Access

Sorafenib inhibits ribonucleotide reductase regulatory subunit M2 (RRM2) in hepatocellular carcinoma cells

Yang, P. M., Lin, L. S. & Liu, T. P., Jan 2020, In : Biomolecules. 10, 1, 117.

Research output: Contribution to journalArticle

Open Access

Tandem mach zehnder directional coupler design and simulation on silicon platform for optical coherence tomography applications

Lu, Y. T., Widhianto, B. Y. B., Hsu, S. H. & Chang, C. C., Feb 2 2020, In : Sensors (Switzerland). 20, 4, 1054.

Research output: Contribution to journalArticle

Open Access

The roles of lipoprotein in psoriasis

Shih, C. M., Chen, C. C., Chu, C. K., Wang, K. H., Huang, C. Y. & Lee, A. W., Jan 29 2020, In : International Journal of Molecular Sciences. 21, 3, 859.

Research output: Contribution to journalArticle

Open Access

Transplantation of mesenchymal stem cells overexpressing fibroblast growth factor 21 facilitates cognitive recovery and enhances neurogenesis in a mouse model of traumatic brain injury

Shahror, R. A., Linares, G. R., Wang, Y., Hsueh, S. C., Wu, C. C., Chuang, D. M., Chiang, Y. H. & Chen, K. Y., Jan 1 2020, In : Journal of Neurotrauma. 37, 1, p. 14-26 13 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

(-)-Phenserine Ameliorates Contusion Volume, Neuroinflammation, and Behavioral Impairments Induced by Traumatic Brain Injury in Mice

Hsueh, S. C., Lecca, D., Greig, N. H., Wang, J. Y., Selman, W., Hoffer, B. J., Miller, J. P. & Chiang, Y. H., Sep 1 2019, In : Cell Transplantation. 28, 9-10, p. 1183-1196 14 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

(−)-Phenserine tartrate (PhenT) as a treatment for traumatic brain injury

Greig, N. H., Lecca, D., Hsueh, S. C., Nogueras-Ortiz, C., Kapogiannis, D., Tweedie, D., Glotfelty, E. J., Becker, R. E., Chiang, Y. H. & Hoffer, B. J., Jan 1 2019, (Accepted/In press) In : CNS Neuroscience and Therapeutics.

Research output: Contribution to journalArticle

Open Access

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Action of Reverse T3 on Cancer Cells

Lin, H. Y., Tang, H. Y., Leinung, M., Mousa, S. A., Hercbergs, A. & Davis, P. J., Jan 1 2019, In : Endocrine Research.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Adipose-derived Stem Cells Attenuates Diabetic Osteoarthritis via Inhibition of Glycation-mediated Inflammatory Cascade

Dubey, N. K., Wei, H-J., Yu, S. H., Williams, D. F., Wang, J. R., Deng, Y. H., Tsai, F. C., Wang, D. P. & Deng, W-P., 2019, In : Aging and Disease.

Research output: Contribution to journalArticle

Open Access

Adverse Outcomes after Major Surgeries in Patients with Diabetes: A Multicenter Matched Study

Lin, C-S., Chang, C-C., Lee, Y-W., Liu, C-C., Yeh, C-C., Chang, Y-C., Chuang, M-T., Chang, T-H., Chen, T-L. & Liao, C-C., Jan 16 2019, In : Journal of Clinical Medicine. 8, 1

Research output: Contribution to journalArticle

A genome-centric approach reveals a novel glycosyltransferase from the ga a07 strain of bacillus thuringiensis responsible for catalyzing 15-o-glycosylation of ganoderic acid a

Chang, T. S., Wang, T. Y., Hsueh, T. Y., Lee, Y. W., Chuang, H. M., Cai, W. X., Wu, J. Y., Chiang, C. M. & Wu, Y. W., Oct 2 2019, In : International Journal of Molecular Sciences. 20, 20, 5192.

Research output: Contribution to journalArticle

Open Access

Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization

Chen, W-T., Hsu, W-T., Yen, M-H., Changou, C. A., Han, C-L., Chen, Y-J., Cheng, J-Y., Chang, T-H., Lee, O. K-S. & Ho, J. H-C., Jan 1 2019, In : Biomaterials. 190-191, p. 1-10 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Altered frontal aslant tracts as a heritable neural basis of social communication deficits in autism spectrum disorder: A sibling study using tract-based automatic analysis

Lo, Y. C., Chen, Y. J., Hsu, Y. C., Chien, Y. L., Gau, S. S. F. & Tseng, W. Y. I., Feb 1 2019, In : Autism Research. 12, 2, p. 225-238 14 p.

Research output: Contribution to journalArticle

Alternative splicing in human cancer cells is modulated by the amiloride derivative 3,5-diamino-6-chloro-N-(N-(2,6-dichlorobenzoyl)carbamimidoyl)pyrazine-2-carboxide

Lee, C. C., Chang, W. H., Chang, Y. S., Yang, J. M., Chang, C. S., Hsu, K. C., Chen, Y. T., Liu, T. Y., Chen, Y. C., Lin, S. Y., Wu, Y. C. & Chang, J. G., Jan 1 2019, In : Molecular Oncology. 13, 8, p. 1744-1762 19 p.

Research output: Contribution to journalArticle

Open Access

A machine learning approach for predicting urine output after fluid administration

Lin, P. C., Huang, H. C., Komorowski, M., Lin, W. K., Chang, C. M., Chen, K. T., Li, Y. C. & Lin, M. C., Aug 1 2019, In : Computer Methods and Programs in Biomedicine. 177, p. 155-159 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)