College of Medical Science and Technology

Projects

Projects per year 2010 2022

• 113 Active
• 859 Finished

Projects per year

Search results

• b - Ministry of Science and Technology

  昆蟲的親緣基因體學: 昆蟲和其他泛甲殼動物的基因體演化(3/3)

  Chen, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 藉由整合多重組學的資料解析與判定人體中未知細菌的基因表現及該細菌在環境中伴演的角色(1/2)

  Wu, Y.

  3/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Multi-Omics Approach for Interpreting the Functional Potentials of Uncharacterized Bacteria in Natural or Man-Made Environments

  Wu, Y.

  3/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • organism 100%
  • genome 91%
  • environmental study 55%
  • genomics 48%
  • twenty first century 45%

• Uncovering the Specific Interactions between DNA Mimic Proteins and Their Target DNA Binding Proteins by Structure-Based Studies(3/3)

  Wang, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • DNA 100%
  • Uracil-DNA Glycosidase 61%
  • Proteins 58%
  • Neisseria 55%
  • DNA-Binding Proteins 44%

• Prediction of Cancer Metastasis Using SVM-Based Model with Quantification of Pathway Changes between Different Disease Statuses

  Chiu, H. & Chang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Support vector machines 100%
  • Gene expression 91%
  • Oncology 55%
  • Proteomics 55%
  • Genomics 43%

• Identification of Human Viral Micrornas and Its Targets by Using Small RNA Sequencing Data Based on RNA Sequence and Structure Features

  Chang, T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Forensic Anthropology 14%
  • Databases 13%
  • Viruses 7%
  • Mammals 6%

• 抑制site-1蛋白酶引發肝癌細胞自我吞噬之研究

  Yang, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Huntingtin-Associated Protein-Regulated Biomarkers in Neurodegenerative Diseases

  Lin, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Proteins 100%
  • Proto-Oncogene Proteins c-bcr 55%
  • Neurodegenerative Diseases 47%
  • Microtubules 39%
  • Calcium 37%

• The Role of Sp1-Regulated Neurosteroidogenesis in Glioma Development

  Hsu, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neurosteroids 100%
  • Glioma 74%
  • Glioblastoma 67%
  • Temozolomide 54%
  • Astrocytes 34%

• 嵌合抗原受體T細胞用於治療人類卵巢癌的免疫療法(2/3)

  Liu, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Fragment-Based Discovery of First-In-Class Small-Molecule Kinase Inhibitors for Targeted Cancer Therapies(2/2)

  Huang, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Multi-Layer Active Contour Model of Supraspinatus Detection in Should Ultrasound Image

  Lo, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Ultrasonics 100%
  • Imaging techniques 44%
  • Tendons 33%
  • Health care 29%
  • Quality control 27%

• ETFDH突變於阿茲海默症之類澱粉前驅蛋白生成和細胞焦亡扮演的角色

  Kao, S.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Galectin-1 in Liver Fibrosis-Promoted Stem-Like Cell Properties and Sorafenib-Refractoriness of Hbv-Related Hepatocellular Carcinoma(I)(1/3)

  Wu, M.

  8/1/18 → 8/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Therapeutic Role of Niemann-Pick Type C2 Protein in Liver Cancer

  Liao, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Liver Neoplasms 70%
  • Carcinogenesis 40%
  • Cholesterol 39%
  • Liver 36%

• Dissection of Synergistic Involvement among Different Guidance Families in Spinal Motor Neuron Development

  Kao, T.

  12/1/13 → 11/30/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Motor Neurons 97%
  • Netrin-1 88%
  • Netrin Receptors 74%
  • Axons 68%
  • Growth Cones 57%

• 腸病毒A71型3A蛋白質與Rab7A蛋白質的交互作用對病毒複製及晚期自噬作用之影響

  Lin, J.

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Job Mobility and Its Determinants among Medical Technology Undergraduates: Educational and Managerial Perspectives

  Liang, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigate Pathogenic Role of Rheumatoid Arthritis, Sjogren$S Syndrome, Systemic Lupus Erythematosus and Its Combined Syndromes from Post-Translational Modification of Serum Proteins: Study of Malondialdehyde Modification

  Lin, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Malondialdehyde 100%
  • Sjogren's Syndrome 94%
  • Systemic Lupus Erythematosus 54%
  • Autoantibodies 23%
  • Peptides 20%

• Injectable Hydrogels of Hyaluronic Acid and Doxycycline Synergistically Down-Regulate the Progression of the Cartilage Degeneration in Rabbit Oa Model

  Chen, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • doxycycline 100%
  • hyaluronic acid 97%
  • knees 26%
  • hydrogels 24%
  • joints (animal) 23%

• Functional Characterization of Niemann-Pick Type C2 Protein in Hepatocellular Carcinoma

  Liao, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Liver Neoplasms 46%
  • Cholesterol 45%
  • Mitogen-Activated Protein Kinase 1 34%
  • Liver 32%

• 探查Pearson氏症候群的基因診斷與在患者衍生細胞上的施行清除粒線體DNA缺失的可行性

  Kao, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer

  Liu, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer(3/3)

  Liu, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• Investigation of Astrocytic Cebpd-Regulated Mirnas and Their Effects on Angiogenesis during Neuroinflammation

  Ko, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Alzheimer Disease 100%
  • MicroRNAs 77%
  • Astrocytes 67%
  • Angiogenesis Inducing Agents 41%
  • Endothelial Cells 40%

• 探討HIV-1反轉錄酉每與新穎先導藥物之複合體結構以利優化作為抗HIV候選藥物

  Liu, C.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以白色念珠菌 alpha-enolase 為目標的單株抗體的人源化與其可能的應用

  Yang, Y.

  2/1/17 → 1/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation for the Molecular Mechanism Involved in the Expression and Impact of Alternatively-Spliced Srsf3 and Map4k4 Variants on Brown Adipogenesis

  Lin, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • serine 100%
  • arginine 95%
  • adipogenesis 82%
  • brown adipose tissue 72%
  • alternative splicing 55%

• Carbamylation Modification of Novel Synovial Fluid and Serum Proteins and Its Role of Anti-Carbanylated Protein Autoantibodies in the Clinic Association of Rheumatoid Arthritis Was Investigated

  Lin, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Rheumatoid Arthritis 100%
  • Protein Carbamylation 74%
  • Synovial Fluid 68%
  • Proteins 44%
  • Autoantibodies 41%

• The Molecular Basis of Senp2 in Regulating Smad4 Sumoylation and Its Functions in Triple Negative Breast Cancer(2/3)

  Chang, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • SUMO-1 Protein 100%
  • Transforming Growth Factor beta 99%
  • Peptide Hydrolases 83%
  • Sumoylation 26%
  • Triple Negative Breast Neoplasms 23%

• The Role of EGFR in Prostate Cancer Progression and Combination Therapy

  Liu, Y. & Chen, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • ErbB Receptors 82%
  • Berberis 26%
  • Neoplastic Stem Cells 16%
  • Neoplasms 15%

• Artificial Neural Network Modeling to Predict the Severity of Oxygen Desaturation and Improve the Nocturnal Hypoxemia after General Anesthesia in Patients with Morbid Obesity

  Lin, C. & Chiu, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Oxygen 100%
  • Hypoxia 94%
  • General Anesthesia 90%
  • Positive-Pressure Respiration 46%
  • Bariatric Surgery 44%

• Islide - a Global Community E-Learning Online

  Li, Y. & Jian, W.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Microscopes 100%
  • Websites 89%
  • Education 88%
  • Medical education 77%
  • E-learning 68%

• The Molecular Basis of Senp2 in Regulating Smad4 Sumoylation and Its Functions in Triple Negative Breast Cancer

  Chang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • SUMO-1 Protein 100%
  • Transforming Growth Factor beta 99%
  • Peptide Hydrolases 83%
  • Sumoylation 26%
  • Triple Negative Breast Neoplasms 23%

• 探討結構化音樂介入模式對泛自閉症症候群幼兒的親子互動與神經語言發展的影響

  Lo, Y.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 腸病毒與宿主間的相互作用對病毒複製複合體形成及病毒複製之作用機轉(3/3)

  Lin, J.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Systemic Analysis on Dynamic Mechanism of Actin Cytoskeleton Organization Regulated Physiological Changes Caused by Physical Stimuli in Mesenchymal Stem Cells

  Ho, J. & Chang, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Actins 100%
  • Mesenchymal Stem Cells 72%
  • Proteins 24%
  • Polymerization 22%
  • Microfilament Proteins 19%

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer

  Liu, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• 產學合作計畫－全基因組定序用於鑑別結核桿菌抗藥性基因試劑組之開 發計畫

  Lin, J.

  6/1/20 → 6/30/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of Anti-RRM-2 Antibody Drug Generation and Their Inhibitory Mechanisms

  Yang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antibodies 100%
  • Single-Chain Antibodies 93%
  • Anti-Idiotypic Antibodies 60%
  • Diphosphates 47%
  • human RRM2B protein 46%

• Functional Characterization of Niemann-Pick Type C2 Protein in Hepatocellular Carcinoma

  Liao, Y.

  1/1/13 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Liver Neoplasms 46%
  • Cholesterol 45%
  • Mitogen-Activated Protein Kinase 1 34%
  • Liver 32%

• Creating the SUMOylated-factor specific antibody and the application in biochemical analysis

  Chang, C.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Using Machine Learning Technique to Evaluate the Impact of Curcumin on the Brain-Gut Interaction in Patients with Tuberous Sclerosis Complex Comorbid to Autism Spectrum Disorders(1/3)

  Lo, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Characterize the E3 Ligase Activity of Znf179 and Its Effect on the Proteinopathies of TDP-43 Protein(2/3)

  Huang, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Ubiquitin-Protein Ligases 100%
  • TDP-43 Proteinopathies 61%
  • Amyotrophic Lateral Sclerosis 47%
  • Frontotemporal Lobar Degeneration 36%
  • Proteins 32%

• The Emerging Impact of Mbnl1-Celf1 Regulatory Circuit Involved in the Development of White Adipocyte, Inducible Brown Adipocytes, and Classical Brown Adipocyte through Post-Transcriptional Regulation.

  Lin, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effects and Molecular Mechanisms of Phthalates (DEHP 和DBP) on the Mitochondrial Function and Genetic Regulation in Ovarian Granulosa Cells and Mouse Embryo

  Tzeng, C. & Kao, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • phthalates 100%
  • granulosa cells 23%
  • reproductive system 17%
  • mice 14%
  • embryo (animal) 10%

• MCPIPs鋅指蛋白家族在人類大腸直腸癌組織的表現及調控Akt訊息傳遞路徑之研究

  Liang, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Inflammatory Microenvironment-Regulated Stemess in Glioblastoma

  Ko, C.

  10/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • CCAAT-Enhancer-Binding Protein-delta 100%
  • Glioma 34%
  • Gallbladder Neoplasms 10%
  • Neoplastic Stem Cells 8%
  • Glioblastoma 8%

• Study the Roles of Npc2 in the Regulation of Hepatic Stellate Cells Activation and Liver Fibrosis

  Liao, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Liver Cirrhosis 82%
  • Cholesterol 41%
  • Down-Regulation 17%
  • Becaplermin 10%
  • alpha-Fetoproteins 9%