College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2023

• 84 Active
• 920 Finished

Projects per year

Search results

• b - Ministry of Science and Technology

  Evaluation of Haptoglobin and Its Subunits as Protein Drugs for Ischemic Heart Diseases

  Cheng, T. & Shih, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Myocardial Ischemia 100%
  • Nanocapsules 63%
  • Pharmaceutical Preparations 40%
  • Haptoglobins 35%
  • Hemoglobins 34%

• Thermodynamic Stability and Folding Kinetics of Membrane Proteins(2/2)

  Chang, Y.

  8/1/18 → 9/30/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • protein 100%
  • membrane 79%
  • trapping 76%
  • folding 48%
  • thermodynamics 22%

• A Investigation of CCL5 (Rantes) in Neurogenesis Mechanism

  Chou, S.

  2/1/14 → 10/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neurons 100%
  • AMP-Activated Protein Kinases 83%
  • Chemokine CCL5 58%
  • Axons 50%
  • Glycogen Synthase Kinases 44%

• Investigation of Genetic and Cellular Factors in Women with Endometriosis(3/3)

  Tzeng, C. & Kao, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Constructing an Assessment Model for Outcome after Carotid Stent Using National Health Insurance Database with Validation by Clinical Data

  Chiu, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 100%
  • Carotid Stenosis 82%
  • Stents 62%
  • Databases 58%
  • Health Insurance 51%

• Using Machine Learning Technique to Evaluate the Impact of Curcumin on the Brain-Gut Interaction in Patients with Tuberous Sclerosis Complex Comorbid to Autism Spectrum Disorders(2/3)

  Lo, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Systematic Characterization and Analysis of the Landscape and Regulation of Rna Editing in Human Cancers

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Inosine 100%
  • RNA Editing 90%
  • Adenosine 73%
  • Neoplasms 57%
  • RNA 51%

• Molecular and Translational Study of L1cam in Metastatic Castraction Resistant Prostate Cancer (Mcrpc)

  Hsieh, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neural Cell Adhesion Molecule L1 100%
  • Prostatic Neoplasms 37%
  • Radiation 14%
  • Phosphorylation 13%
  • Bone Neoplasms 11%

• Genetic Polymorphisms in microRNA and Risk of the Post-Thrombolytic Hyperglycemia in Acute Ischemic Stroke and Its Prognosis Study

  Hsieh, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hyperglycemia 100%
  • MicroRNAs 92%
  • Stroke 80%
  • Single Nucleotide Polymorphism 42%
  • Small Untranslated RNA 10%

• 探討高尿酸血症(痛風)病人與日後罹患阿茲海默症疾病風險的相關性研究

  Yang, W.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Potential Therapeutic Effect of Curcumin, a Natural Mtor Inhibitor, in Tuberous Sclerosis Complex

  Lee, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Curcumin 100%
  • Tuberous Sclerosis 99%
  • TOR Serine-Threonine Kinases 65%
  • Raptors 22%
  • Knockout Mice 20%

• Disease Trajectories and Its Association with Metabolic Dysfunction of Prostate Cancer Men Following Androgen Deprivation Therapy and the Potential of Pharmacological Medication in Preventing Metastatic Diseases.

  Shao, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Investigate the Role of N-Linked Glycosylated Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (Ceacam6) in Egf Receptor Signaling and the Implication in Oral Cancer Therapy

  Wu, M.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Carcinoembryonic Antigen 100%
  • Cell Adhesion Molecules 98%
  • ErbB Receptors 71%
  • Glycosylation 38%
  • Neoplasm Metastasis 11%

• Analysis and Therapy of Post-Tbi Insomnia – Animal Study of Music Therapy as a Remedy

  Chen, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of the Intrinsic Molecular Mechanisms of ETV6 That Contribute to Suppression of Metastasis and Sensitivity of Chemotherapy in Prostate Cancer

  Liu, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • Neoplasm Metastasis 28%
  • ras Genes 16%
  • Nuclear Receptor Co-Repressor 2 11%
  • Drug Therapy 11%

• Study of Anti-RRM-2 Antibody Drug Generation and Their Inhibitory Mechanisms

  Yang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antibodies 100%
  • Single-Chain Antibodies 93%
  • Anti-Idiotypic Antibodies 60%
  • Diphosphates 47%
  • human RRM2B protein 46%

• Role of Ribonucleotide Reductase (Rnr) in Skeletal Muscle with Age: the Functionality of Rrm2b in Repair and Regeneration

  Chen, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Skeletal Muscle 100%
  • Sarcopenia 58%
  • Regeneration 52%
  • Muscles 47%
  • Muscular Diseases 33%

• The Role of Neuropilin-1 Glycosylation in Galectin-1 Induced Activation of Hepatic Stellate Cells and Liver Fibrosis(3/3)

  Wu, M.

  8/1/16 → 9/30/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Galectin 1 100%
  • Neuropilin-1 68%
  • Liver Cirrhosis 28%
  • Platelet-Derived Growth Factor Receptors 20%
  • thiodigalactoside 12%

• Assessing the Mechanism and Magnifying the Combined Effects of Exercise and Deep Brain Stimulation for Parkinson'S Disease

  Chen, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Deep Brain Stimulation 100%
  • Parkinson Disease 72%
  • Neurodegenerative Diseases 18%
  • Neuroprotection 11%
  • Neuroprotective Agents 10%

• Identification of Human Viral Micrornas and Its Targets by Using Small RNA Sequencing Data Based on RNA Sequence and Structure Features

  Chang, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Forensic Anthropology 14%
  • Databases 13%
  • Viruses 7%
  • Mammals 6%

• Establish the Research Platform for Studying Triple-Negative Breast Tumor Microenvironment Regulation: the Hyaluronan Synthase-3 Mediated Antitumor Effects as an Example.

  Ho, Y. & Wu, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Gene Expression 46%
  • Tumor Microenvironment 40%
  • Hyaluronan Synthases 30%
  • Fibroblasts 29%

• 寶寶玩音樂!音樂環境介入對幼兒神經語言發展的影響

  Lo, Y.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Functional Studies of ZNF179 in Neurons in vitro and in vvo

  Lee, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Huntington Disease 100%
  • Knockout Mice 82%
  • Spatial Learning 72%
  • Spatial Memory 66%
  • (2-azidomethyl)phenylacetyl 64%

• Radiogenomics of Malignant Gliomas by Linking Physiological Mr Imaging, Histopathological Patterns, and Genetic Alternations: a Translational Study from Rat to Man

  Chen, C., Tsai, P., Liu, H., Lin, Y. & Chiang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glioblastoma 100%
  • Glioma 51%
  • Biomarkers 36%
  • Multiparametric Magnetic Resonance Imaging 15%
  • Neoplasms 14%

• The Role of Neuropilin-1 Glycosylation in Galectin-1 Induced Activation of Hepatic Stellate Cells and Liver Fibrosis

  Wu, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Galectin 1 100%
  • Neuropilin-1 68%
  • Liver Cirrhosis 28%
  • Platelet-Derived Growth Factor Receptors 20%
  • thiodigalactoside 12%

• A Tmu/Nih Integrated Research Project (4-2)─ Establishment of Diagnostic Tools and Treatment Strategies of Mild Traumatic Brain Injury

  Chiu, W., Chiang, Y. & Hung, K.

  8/1/11 → 9/5/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • N-nitrosoiminodiacetic acid 18%
  • Animal Models 15%
  • Taiwan 10%
  • Postural Balance 8%
  • Population 8%

• Study of Anti-Αlpha-Enolase I Antibodies on Cancers and Their Potential Applications

  Yang, Y. & Leu, S.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphopyruvate Hydratase 100%
  • Antibodies 32%
  • Single-Chain Antibodies 13%
  • Neoplasms 10%
  • Proteins 9%

• Studies on the Mechanisms of Histamine N-Methyl-Transferase (Hnmt) as a Novel Molecular Marker to Help Clinician for Identifying of Herceptin Responder in Breast Cancer Patients(1/3)

  Ho, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Identification of Rewired Apc Mutation Signaling Network in Chemotherapy Resistant Response in Colorectal Cancer( III )

  Huang, T.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Wnt5a and Hsp90 in the Wnt/Beta-Catenin Signaling Pathway of Colorectal Cancer( III )

  Lee, K.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Using Genome-Wide Linkage Analysis and Next Generation Sequencing Approaches to Identify the Genes Responsible for the Familial Colorectal Cancer Type X

  Wang, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Translational Genomic Approaches in Endometriosis

  Tzeng, C., Huang, Y., Shen, S., Yang, W., Li, Y., Yeh, C. & Kao, S.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • endometrium 100%
  • microRNA 90%
  • stem cells 61%
  • cell adhesion molecules 54%
  • metastasis 35%

• ADAM9 調節 integrin b4 之轉換率以促使前列腺癌細胞移動及浸潤之研究(3/3)

  Sung, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • metastasis 100%
  • integrins 89%
  • neoplasm progression 42%
  • neoplasms 38%
  • neoplasm cells 32%

• Hmga2, a New Target of Thyroid Hormone-Induced Progression in Colorectal Cancers

  Lin, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • Thyroid Hormones 82%
  • tetraiodothyroacetic acid 76%
  • Colorectal Neoplasms 47%
  • Integrins 31%

• Drug Discovery and Pharmacological Investigation of Selective Hdac1 and 2 Inhibitors as Novel Anticancer Drugs

  Pan, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone 100%
  • Antitumor 34%
  • Antineoplastic Agent 33%
  • Drug 29%
  • DNA Sequence 19%

• Application of Data Mining Techniques for National Health Insurance Research Database Analysis to Develop Risk Assessment System of Major Postoperative Complications

  Lin, C., Liao, C. & Chiu, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Asthma 100%
  • Postoperative Complications 77%
  • Odds Ratio 41%
  • National Health Programs 27%
  • Mortality 25%

• Role of miR-21 in Regulating TET I-Hydroxymethylcytosine and Chemotherapeutic Response in Colorectal Cancer (I)

  Yang, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colorectal Neoplasms 100%
  • 5-hydroxymethylcytosine 84%
  • APC Genes 58%
  • DNA Methylation 55%
  • Adenomatous Polyposis Coli 51%

• Gene Knock out Mice Model for Studying the Molecular Mechanisms of Early Onset Breast Tumor Microenvironment Regulation.

  Wu, C., Ho, Y. & Tu, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • breast 100%
  • cancer 97%
  • tumors 59%
  • fibroblasts 33%
  • genes 31%

• Investigations on the Cellular Mechanisms of Ccl5 in Memory Formation and Its Role in Alzheimer’s Disease 3/3

  Chou, S.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chemokine CCL5 100%
  • Alzheimer Disease 79%
  • Memory 30%
  • Neurons 14%
  • Knockout Mice 11%

• Study of the Role of L1cam on Neuroendocrine Prostate Cancer Progression

  Hsieh, C.

  8/1/18 → 9/30/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • Neural Cell Adhesion Molecule L1 91%
  • Castration 16%
  • Phenotype 9%
  • RNA-Binding Proteins 5%

• The Development and Preclinical Evaluation of a Theronostic Nanovehicle Drug for Treating Acute Myeloid Leukemia and Leukemia Stem Cells.( III )

  Yen, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Characterization of Multiple Functions of Plzf in Brain Development(1/3)

  Lee, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Activation Autophagy by the Combination of a Histone Deacetylase Inhibitor and Radiation Limits BNIP3 Regulation in Triple-Negative Breast Cancer Cells and Orthotopic Mouse Model

  Chiu, H. & Ho, Y.

  8/1/15 → 6/30/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Triple Negative Breast Neoplasms 100%
  • Histone Deacetylase Inhibitors 97%
  • Ionizing Radiation 42%
  • Autophagy 39%
  • human ERBB2 protein 25%

• The Role of Galectin-3 in Ceacam6 Enhanced Egfr Signaling and Its Implication in Head and Neck Cancer Therapy

  Wu, M.

  8/1/18 → 7/30/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Carcinoembryonic Antigen 100%
  • Cell Adhesion Molecules 98%
  • Galectin 3 64%
  • Squamous Cell Carcinoma of Head and Neck 43%
  • Cetuximab 24%

• The Development and Preclinical Evaluation of a Theronostic Nanovehicle Drug for Treating Acute Myeloid Leukemia and Leukemia Stem Cells (I)

  Yen, Y., Cheng, T. & Wu, A. T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Leukemia 100%
  • haptoglobin-hemoglobin complex 54%
  • Calicheamicins 53%
  • Neoplasms 49%
  • Multifunctional Nanoparticles 49%

• Smart Mouth Guard 3D Drug Delivery and Wound Dressing Device Development (Project 1)

  Deng, W. & Ou, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mouth Protectors 100%
  • Bandages 50%
  • Equipment and Supplies 38%
  • Pharmaceutical Preparations 26%
  • Periodontitis 26%

• (100SB205)The Resource Center Project from the Joint Biorepository of Taipei Medical University Affiliated and Alliance Hospitals

  Li, Y.

  12/1/11 → 3/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • translational medical research 100%
  • information systems 66%
  • information management 14%
  • colorectal neoplasms 13%
  • breast neoplasms 12%

• A Revolutionary Approach for Disease-Associated Pathways Identification: from Genome-Wide Network Construction, Pathway Discovery, to Pathway-Based Analysis and Validation

  Lee, Y. G.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Genes 100%
  • Genomics 43%
  • Genetics 14%
  • Biotechnology 13%
  • Microarrays 11%

• The Molecular Basis of Senp2 in Regulating Smad4 Sumoylation and Its Functions in Triple Negative Breast Cancer

  Chang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • SUMO-1 Protein 100%
  • Transforming Growth Factor beta 99%
  • Peptide Hydrolases 83%
  • Sumoylation 26%
  • Triple Negative Breast Neoplasms 23%

• The role of DDX3 in human papillomavirus-infected lung tumorigenesis

  Lee, H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Papillomavirus Infections 100%
  • Cisplatin 96%
  • Lung 86%
  • Neoplasms 63%
  • Gastropoda 47%