College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2024

• 73 Active
• 1019 Finished

Projects per year

Search results

• b - Ministry of Science and Technology

  Drug Discovery and Pharmacological Investigation of Selective Hdac1 and 2 Inhibitors as Novel Anticancer Drugs

  Pan, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone 100%
  • Antitumor 34%
  • Antineoplastic Agent 33%
  • Drug 29%
  • DNA Sequence 19%

• Design and Potency Optimization of Kinase Inhibitors for Cancer Treatment(1/3)

  Hsu, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Identification of Human Viral Micrornas and Its Targets by Using Small RNA Sequencing Data Based on RNA Sequence and Structure Features

  Chang, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Forensic Anthropology 14%
  • Databases 13%
  • Viruses 7%
  • Mammals 6%

• Constructing an Assessment Model for Outcome after Carotid Stent Using National Health Insurance Database with Validation by Clinical Data

  Chiu, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 100%
  • Carotid Stenosis 82%
  • Stents 62%
  • Databases 58%
  • Health Insurance 51%

• The Effect of Long Acting GnRH Agonist Treatment on Mitochondrial Function

  Tzeng, C., Hsieh, R. & Kao, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • hormone agonists 100%
  • mitochondria 91%
  • pathophysiology 42%
  • granulosa cells 38%
  • agonists 32%

• Discovery of multitarget inhibitors for colorectal cancer treatment using Pharmalogs

  Hsu, K. & Cheng, Y.

  2/1/16 → 1/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Normoxic Expression of Hypoxia Inducible Factor 1-Α and Endoplasmic Reticulum Stress Associated Protein Grp-78 in the Modulation of Drug-And Radioresistance Acquisition of Human Hepatoma Cell Lines

  Chiou, J. & Wu, A. T.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hypoxia-Inducible Factor 1 100%
  • 1-phenyl-3,3-dimethyltriazene 55%
  • Reticulum 33%
  • Research Design 31%
  • Paclitaxel 26%

• New Drug Development for Mtbi

  Chiu, W., Chiang, Y. & Hsu, F.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Herbal Medicine 68%
  • Wounds and Injuries 49%
  • Migraine Disorders 40%
  • Oxazoles 36%

• Generate Anti-Fibroblast Growth Factor Receptor 2 (Fgfr2) Antibody Drugs and Study on Their Potential Application against Gastric Cancer

  Lee, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Noninvasive Blood Pressure Estimation with Photoplethysmography

  Chiu, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Photoplethysmography 100%
  • Blood pressure 82%
  • Wearable technology 21%
  • Neural networks 19%
  • Intensive care units 8%

• 利用基因網絡分析尋找假定蛋白質 （hypothetical protein)與抗藥性的關係

  Wu, Y.

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建立以結構為基礎之藥物篩選模型並應用於研發新穎性蛋白激酶抑制劑

  Hsu, K.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研發急性骨髓性白血病的新穎性CDK8抑制劑並以毒理測試評估其安全性

  Pan, S.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用次世代定序研究細菌與黴菌菌相與黴菌性鼻竇炎的關聯(2/3)

  Chang, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Combination Treatment of Tetrac- and Cetuximab-Induced Anti-Proliferation in Colorectal Cancer with Different APC Status (I)

  Lin, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tetraiodothyroacetic acid 100%
  • Cetuximab 77%
  • Adenomatous Polyposis Coli 38%
  • Colorectal Neoplasms 28%
  • Integrins 16%

• Computational Analysis of Regulatory Networks of Extracellular Matrix in Endometrial Cancer Development and Discovery of Potential Drugs for Therapy

  Chang, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Prediction of Cancer Metastasis Using SVM-Based Model with Quantification of Pathway Changes between Different Disease Statuses

  Chiu, H. & Chang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Support vector machines 100%
  • Gene expression 91%
  • Oncology 55%
  • Proteomics 55%
  • Genomics 43%

• 基於深度學習與機器學習混合分析多體學數據於癌症精準醫學治療之應用評估(2/2)

  Chang, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用PLA2G6基因嵌入小鼠研究第十四型帕金森病分子病理機轉與治療(1/3)

  Yeh, T.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Tmu Spark Taiwan-Anchor University Program

  Yen, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • industry 100%
  • Licensing of intellectual property 79%
  • budget plan 71%
  • expert 54%
  • basic research 47%

• 藉由整合多重組學的資料解析與判定人體中未知細菌的基因表現及該細菌在環境中伴演的角色(1/2)

  Wu, Y.

  3/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以新穎mito-FD-CRISPR/Cas9系統開發粒線體基因編輯模式

  Lee, C.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effect of Proteoglycans on Neurite Outgrowth and Functional Recovery in an Animnal Model with Spinal Cored Injury

  Yang, W.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neuronal Outgrowth 100%
  • Annexin A6 82%
  • perlecan 72%
  • chondroitin sulfate glycosaminoglycan 63%
  • Chondroitin Sulfate Proteoglycans 53%

• 探討家族遺傳性肌萎縮性脊髓側索硬化症的基因突變對胚胎發育的影響及其應用

  Kao, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討長鏈非編碼RNA LncHIFCAR-HIF1A 基因調控網路及其於口腔癌進程之臨床價值(2/2)

  Shih, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Using Genome-Wide Linkage Analysis and Next Generation Sequencing Approaches to Identify the Genes Responsible for the Familial Colorectal Cancer Type X

  Wang, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Crystal Structures and Functional Studies of Novel Glycosyltransferases from Staphylococcus Aureus

  Liu, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycosyltransferases 100%
  • Staphylococcus aureus 64%
  • Fibrin 30%
  • Cathepsin G 22%
  • Minisatellite Repeats 19%

• 腸道菌叢-腸道代謝體-宿主細胞轉錄後事件組成之調控網絡於維持腸道平衡或誘發腸道細胞癌化特性之探究

  Lin, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Preclinical and Clinical Trial Evaluation for an in vitro Diagnostic Kit of Endometriosis (II)

  Yang, W.

  12/1/13 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Role of Sp1 in Cancer Drug Resistance( II )

  Chuang, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigate Pathogenic Role of Rheumatoid Arthritis, Sjogren$S Syndrome, Systemic Lupus Erythematosus and Its Combined Syndromes from Post-Translational Modification of Serum Proteins: Study of Malondialdehyde Modification

  Lin, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Malondialdehyde 100%
  • Sjogren's Syndrome 94%
  • Systemic Lupus Erythematosus 54%
  • Autoantibodies 23%
  • Peptides 20%

• To Investigate the Mode of Galectin-1 and Neuropilin-1 Interactions in Carcinoma-Associated Fibroblasts and Its Implications in Oral Cancer Therapy

  Wu, M.

  8/1/15 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neuropilins 100%
  • Fibroblasts 91%
  • Polysaccharides 77%
  • Carcinoma 72%
  • Mouth Neoplasms 22%

• Injectable Hydrogels of Hyaluronic Acid and Doxycycline Synergistically Down-Regulate the Progression of the Cartilage Degeneration in Rabbit Oa Model

  Chen, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • doxycycline 100%
  • hyaluronic acid 97%
  • knees 26%
  • hydrogels 24%
  • joints (animal) 23%

• Investigation of K63-Linked Deubiquitination Effects of Mcpip Family Members and Their Genetic Profiles through Tcga Data Analysis

  Liang, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • TNF Receptor-Associated Factor 2 100%
  • Ubiquitin 82%
  • Ubiquitination 71%
  • Genetic Profile 63%
  • Signal Transduction 38%

• 探討引導受體與配體之間的cis-弱化互動對脊髓運動神經迴路形成的影響(1/3)

  Kao, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Exploration and Investigation of Brown Adipogenesis-Associated Alternative Splicing Network by Transcriptome Analyses

  Lin, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • brown adipose tissue 100%
  • adipogenesis 64%
  • alternative splicing 41%
  • brown adipocytes 34%
  • obesity 25%

• The Lncrna Lnchifcar–Hif1a Regulatory Network and Its Clinical Relevance in Oral Cancer Progression(1/2)

  Shih, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Using the Integrated Hospital Data for Implementing and Evaluating of Early Detection of Influenza Epidemic

  Lo, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Pathogenic Role of Posttranslational Modification of Plasma N-Linked Glycoprotein to Rheumatoid Arthritis Combined Sjogren$S Syndrome Was Investigated

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sjogren's Syndrome 100%
  • Rheumatoid Arthritis 73%
  • Post Translational Protein Processing 62%
  • Blood Proteins 19%
  • Proteins 14%

• Genetic Polymorphisms in microRNA and Risk of the Post-Thrombolytic Hyperglycemia in Acute Ischemic Stroke and Its Prognosis Study

  Hsieh, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hyperglycemia 100%
  • MicroRNAs 92%
  • Stroke 80%
  • Single Nucleotide Polymorphism 42%
  • Small Untranslated RNA 10%

• The Effect of Wnt Signals and Programmed Cell Death on the Organization of Neural Circuit in Spinal Motor Neurons

  Kao, T.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Motor Neurons 100%
  • Wnt Receptors 73%
  • Ephrins 46%
  • Nerve Growth Factors 42%
  • Growth Cones 40%

• 新神經與疼痛相關蛋白抗體開發-抗酸敏感離子通道3蛋白的抗體製備與定性

  Yang, Y.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of Diffusion Tensor Imaging to Study the White Matter Integrity and Coherence in Resting Electroencephalography

  Hsu, R.

  8/1/12 → 1/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electroencephalography 100%
  • Brain 42%
  • Magnetic resonance 40%
  • Imaging techniques 39%
  • Fibers 26%

• Investigation on the Suppressive Mechanisms of Novel Anti-Glypican3 Antibody Drugs

  Yang, Y.

  8/1/14 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glypicans 100%
  • Hepatocellular Carcinoma 20%
  • Antibodies 18%
  • Single-Chain Antibodies 10%
  • Heparan Sulfate Proteoglycans 10%

• Study and Implementation of Patient Privacy Protection under the Framework for Electronic Medical Records Exchange in Taiwan

  Liu, C.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electronic medical equipment 100%
  • Data privacy 38%
  • Health insurance 14%
  • Virtual private networks 13%
  • Law enforcement 10%

• 子宮內膜異位症體外血清診斷試劑開發計畫(2/2)

  Yang, W.

  4/1/16 → 1/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Occupation Choices, Work Characteristics, and Career Success of Medical Technology Undergraduates from Gender and Generational Perspectives (K01)

  Liang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • medical technology 100%
  • bachelor 44%
  • graduate 29%
  • gender role 22%
  • Taiwan 19%

• Injectable Hydrogels of Hyaluronic Acid and Doxycycline Synergistically Down-Regulate the Progression of the Cartilage Degeneration in Rabbit Oa Model

  Chen, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • doxycycline 100%
  • hyaluronic acid 97%
  • knees 26%
  • hydrogels 24%
  • joints (animal) 23%

• Crowdhealth Project: Using Health-Related Big Data for Supporting Policy Making Decisions 全文電子檔： [全文下載1]

  Shabbir, S. A.

  4/1/18 → 3/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Synergistic Integration of Ephrin and Netrin Signals in the Developing Nervous System

  Kao, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Netrins 100%
  • Ephrins 91%
  • Growth Cones 79%
  • Motor Neurons 48%
  • Ephrin-B2 41%