College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2024

• 73 Active
• 1019 Finished

Projects per year

Search results

• b - Ministry of Science and Technology

  攝護腺癌之精準代謝治療(2/3)

  Kung, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Translational Genomic Approaches in Endometriosis

  Tzeng, C., Huang, Y., Li, Y., Yang, W., Shen, S. & Kao, S.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • endometrium 100%
  • microRNA 90%
  • stem cells 61%
  • cell adhesion molecules 54%
  • metastasis 35%

• Drug Discovery and Pharmacological Investigation of Novel Selective Hdac Inhibitors as Anticancer Drugs

  Pan, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of EGFR in Prostate Cancer Progression and Combination Therapy

  Liu, Y. & Chen, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • ErbB Receptors 82%
  • Berberis 26%
  • Neoplastic Stem Cells 16%
  • Neoplasms 15%

• Mechanisms and Therapeutic Strategies of Pd-L1 Expression in Oral Cancers( I )(1/3)

  Lin, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• HMGA2, a New Target of Thyroid Hormone-Induced Progression in Colorectal Cancers(2/3)

  Lin, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • Thyroid Hormones 75%
  • tetraiodothyroacetic acid 70%
  • Colorectal Neoplasms 43%
  • Catenins 31%

• 新穎性pan-HDAC 抑制劑抑制血管新生之藥物研發與藥理作用機轉(3/3)

  Pan, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylase Inhibitors 100%
  • Histone Deacetylases 39%
  • 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 20%
  • Animal Models 18%
  • Drug Discovery 17%

• Role of Androgen on Breast Cancer Development and Treatment

  Lin, H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Androgen 100%
  • Testosterone 31%
  • Signal Transduction 21%
  • Chemopreventive 9%
  • Silencing RNA 8%

• 再生醫學科技發展計畫－全身安全性異體移植策略之細胞治療產品開發:標靶醫療未滿足慢性發炎相關疾病-糖尿病/褥瘡/嚴重燒燙傷之傷口癒合與多發性硬化症(1/3)

  Yen, Y.

  5/1/17 → 4/30/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Discovery of Selective Inhibitors for Oncoprotein Kinases

  Hsu, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Protein Kinases 100%
  • Phosphotransferases 92%
  • Oncogene Proteins 72%
  • Pharmaceutical Preparations 35%
  • Neoplasms 24%

• Integrated Bioinformatics Approaches to Study the Mechanisms and Discover Drugs of Hcv-Induced Type 2 Diabetes Mellitus(3/3)

  Hsu, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 選擇性抗癌標靶藥物HDAC6抑制劑臨床前試驗研究

  Pan, S.

  12/1/17 → 10/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Hmga2, a New Target of Thyroid Hormone-Induced Progression in Colorectal Cancers

  Lin, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • Thyroid Hormones 82%
  • tetraiodothyroacetic acid 76%
  • Colorectal Neoplasms 47%
  • Catenins 34%

• HMGA2, a New Target of Thyroid Hormone-Induced Progression in Colorectal Cancers

  Lin, H., Chang, T. & Yen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • Thyroid Hormones 75%
  • tetraiodothyroacetic acid 70%
  • Colorectal Neoplasms 43%
  • Catenins 31%

• Potential Application of the Staphylococcus aureus DNA Mimic Protein Saugi in Combating Human Viral Disease

  Wang, H.

  10/1/13 → 9/30/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • DNA 100%
  • Uracil-DNA Glycosidase 92%
  • DNA Repair Enzymes 83%
  • Neisseria 83%
  • Staphylococcus aureus 77%

• The Effects and Molecular Mechanisms of Phthalates (DEHP 和DBP) on the Mitochondrial Function and Genetic Regulation in Ovarian Granulosa Cells and Mouse Embryo

  Tzeng, C. & Kao, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • phthalates 100%
  • granulosa cells 23%
  • reproductive system 17%
  • mice 14%
  • embryo (animal) 10%

• Investigation of the Cytotoxic Mechanism of Photorhabdus Luminescens Pirapl and Pirbpl Toxins by Using Structural and Proteomic Approaches

  Wang, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Photorhabdus 100%
  • Insecta 30%
  • Aedes 24%
  • toxin V 19%
  • Xenorhabdus 17%

• 新穎性DYRK1A抑制劑於阿茲海默症之機轉探討(2/3)

  HuangFu, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies of Prostate Cancer Progression after Androgen-Deprivation Therapy and Development of Cancer Immunotherapy via Anti-Inflammation Approaches

  Tsai, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Androgen Receptors 100%
  • Prostatic Neoplasms 61%
  • Inflammation 54%
  • Androgens 42%
  • Neoplasms 39%

• 新穎性DYRK1A抑制劑於阿茲海默症之機轉探討(3/3)

  HuangFu, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以深度學習預測抗糖尿病胜肽之免疫生物資訊學研究

  Su, E. C.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討長鏈非編碼RNA在癌症代謝中調控的角色(2/3)

  Kung, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Ddx3 in Cetuximab Resistance in Kras-Mutated and -Wild-Type Colorectal Cancer ( I )

  Lee, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cetuximab 100%
  • Colorectal Neoplasms 18%
  • Animal Models 10%
  • Phosphatidylinositol 3-Kinases 9%
  • Tumor Burden 8%

• Investigation of the Functions of Brain Finger Protein, Znf179, in Embryo Development and in Adult Brain

  Lee, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Blood Vessels 100%
  • Embryonic Structures 92%
  • Knockout Mice 77%
  • Spatial Learning 68%
  • BFP ring finger protein 64%

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯研究-探討α9尼古丁受體基因表現在乳癌病人血液循環腫瘤細胞/游離DNA於乳癌治療的應用(2/3)

  Tzeng, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effectiveness of Hormonal Therapy on Prostate Cancer Bone Metastasis Determined by Klf4

  Liu, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies of Roles of SIRT7 in Cancer Biology

  Tsai, Y.

  1/1/14 → 10/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • neoplasms 100%
  • neoplasm cells 59%
  • Biological Sciences 47%
  • cancer therapy 31%
  • drug development 27%

• 闡明CEEMT(環境豐富化合併音樂療法) 對腦外傷後認知、憂鬱與焦慮的影響與機制探討

  Chen, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討利用類黃酮作為新穎DYRK1B抑制劑在惡性胰臟癌之療效

  HuangFu, W.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Roles of Microrna96 in Tgfβ-Mediated Tumor Progression

  Tsai, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Transforming Growth Factors 100%
  • Neoplasms 26%
  • Prostatic Neoplasms 21%
  • Castration 15%
  • Androgen Receptors 14%

• 研究PKLR促進前列腺癌神經內分泌分化之代謝途徑及其治療角色(1/3)

  Liu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Inflammatory Microenvironment-Regulated Stemess in Glioblastoma

  Ko, C.

  10/1/16 → 9/30/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • CCAAT-Enhancer-Binding Protein-delta 100%
  • Glioma 36%
  • Gallbladder Neoplasms 11%
  • Neoplastic Stem Cells 9%
  • Glioblastoma 8%

• To See Is to Believe- Visualization of the Spectrum on Chronic Kidney Disease (II)

  Jian, W., Li, Y. & Wu, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Health care 100%
  • Data visualization 75%
  • Patient treatment 50%
  • Disease control 49%
  • Health insurance 49%

• 利用電子病歷與個人健康資訊建構慢性腎臟病人之紅血球生成刺激劑智慧給藥模型(第二、三年延續案)

  Huang, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The First Randomized Controlled Clinical Trial for Computerized Decision Support System (II)

  Li, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Contrast Media 100%
  • Drug-Related Side Effects and Adverse Reactions 60%
  • Clinical Decision Support Systems 56%
  • Physicians 54%
  • Randomized Controlled Trials 43%

• 攝護腺癌之精準代謝治療(1/3)

  Kung, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究CHRM4作為前列腺癌新穎生物標靶之應用與治療策略

  Liu, Y.

  6/1/21 → 5/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of the Intrinsic Molecular Mechanisms of ETV6 That Contribute to Suppression of Metastasis and Sensitivity of Chemotherapy in Prostate Cancer

  Liu, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • Neoplasm Metastasis 28%
  • ras Genes 16%
  • Nuclear Receptor Co-Repressor 2 11%
  • Drug Therapy 11%

• The Study of Therapeutic Effects for Stroke with Phenserine, an Amyloid Precursor Protein Inhibitor, in Rodent Focal Cerebral Ischemia Model

  Chang, C. & Chiang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • phenserine 100%
  • Stroke 75%
  • Amyloid beta-Protein Precursor 49%
  • Stem Cells 31%
  • pifithrin 27%

• The Pre-Clinical Assessment of the Anti-Tumor Efficacy of a Protein Vaccine and Mesenchymal Stem Cell Combined Therapy, Using Non-Invasive Molecular Imaging Technology

  Wu, A. T. & Deng, W.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Vaccines 100%
  • Molecular Imaging 78%
  • Neoplasms 75%
  • Suicide 61%
  • Mesenchymal Stem Cells 59%

• Investigate Pathogenic Role of Rheumatoid Arthritis, Sjogren's Syndrome, Systemic Lupus Erythematosus and Its Combined Syndromes from Post-Translational Modification of Novel Synovial Fluid and Serum Proteins---Study of 4-Hydroxy-2-Nonenal Modificatio

  Lin, C. & Chang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • rheumatoid arthritis 100%
  • lupus erythematosus 99%
  • autoantibodies 49%
  • proteins 31%
  • autoimmune diseases 29%

• Assessing the Mechanism and Magnifying the Combined Effects of Exercise and Deep Brain Stimulation for Parkinson'S Disease

  Chen, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Deep Brain Stimulation 100%
  • Parkinson Disease 72%
  • Neurodegenerative Diseases 18%
  • Neuroprotection 11%
  • Neuroprotective Agents 10%

• Investigation of Genetic and Cellular Factors in Women with Endometriosis(3/3)

  Tzeng, C. & Kao, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Novel Lifr Axis in Metabolism Unhinged and Neuroendocrine Differentiation of Prostate Cancer(I)

  Liu, Y.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Mechanistic Action of DDX3 in Colorectal Tumor Progression

  Lee, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Catenins 100%
  • Drug Resistance 26%
  • Neoplasms 25%
  • Colorectal Neoplasms 22%
  • Carcinogenesis 22%

• 利用結構生物學與蛋白質體學探討植物菌質體 PHYL1 交互作用蛋白質

  Wang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Characterize the E3 Ligase Activity of Znf179 and Its Effect on the Proteinopathies of TDP-43 Protein(2/3)

  Huang, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Ubiquitin-Protein Ligases 100%
  • TDP-43 Proteinopathies 61%
  • Amyotrophic Lateral Sclerosis 47%
  • Frontotemporal Lobar Degeneration 36%
  • Proteins 32%

• 以基因剪輯技術(CRISPR/Cas9)應用於費城染色體為標靶之慢性骨髓性白血病治療

  Lee, C.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發新穎TBK1抑制劑並評估其抑制胰臟癌的功效與探討機轉

  Hsu, K.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - Ministry of Science and Technology