College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2023

• 90 Active
• 914 Finished

Projects per year

Search results

• b - Ministry of Science and Technology

  Mechanisms by Which Enterovirus-Host Interactions Form Viral Replication Organelles and Regulate Viral Replication

  Lin, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Organelles 100%
  • Enterovirus 53%
  • Intracellular Membranes 29%
  • Host Microbial Interactions 29%
  • Membranes 27%

• 以CRISPR/Cas9建立exosome-free研究模式探討外泌體(exosome)調控三陰性乳癌轉移機制

  Lee, C.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Mechanistic Action of DDX3 in Colorectal Tumor Progression

  Lee, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • beta Catenin 100%
  • Catenins 46%
  • Drug Resistance 45%
  • Neoplasms 43%
  • Colorectal Neoplasms 39%

• Application of Diffusion Tensor Imaging to Study the White Matter Integrity and Coherence in Resting Electroencephalography

  Hsu, R. & Wang, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electroencephalography 100%
  • Brain 42%
  • Magnetic resonance 40%
  • Imaging techniques 39%
  • Fibers 26%

• The Role of DDX3 in Human Papillomavirus-Infected Lung Tumorigenesis

  Lee, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Papillomavirus Infections 100%
  • Cisplatin 96%
  • Lung 86%
  • Neoplasms 63%
  • Gastropoda 47%

• 以深度學習分析臨床特徵及胚胎品質以提升人工受孕懷孕率之系統性預測方法開發

  Su, E. C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 闡明Hiltonol為主的複合式用藥在肺癌生長，轉移和腫瘤微環境中的作用。

  Chang, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating a key switch between immune-overactivation and tumorigenesis

  Chang, S.

  2/1/16 → 1/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Klf10 Alters Metabolic Pathways in Genetic-Deficient Mice and Human Pancreatic Ductal Carcinomas

  Chang, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 1-(7-(2-hydroxyethyl)dodecahydro-3a-methyl-1H-benz(e)inden-3-yl)ethanone 100%
  • Metabolic Networks and Pathways 49%
  • Pancreatic Neoplasms 46%
  • Knockout Mice 45%
  • Insulin Resistance 40%

• The Role of Cytoplasmic APe1 in Tumor Malignancy, Drug Resistance and Lung Cancer Prognosis

  Lee, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • NF-kappa B 100%
  • Oxidation-Reduction 45%
  • Cell Nucleus Active Transport 44%
  • Lung Neoplasms 37%
  • Neoplasms 36%

• The Role of Ddx3 in Cetuximab Resistance in Kras-Mutated and -Wild-Type Colorectal Cancer ( I )

  Lee, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cetuximab 100%
  • Colorectal Neoplasms 18%
  • Animal Models 10%
  • Phosphatidylinositol 3-Kinases 9%
  • Tumor Burden 8%

• Roles of Microrna96 in Tgfβ-Mediated Tumor Progression

  Tsai, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Transforming Growth Factors 100%
  • Neoplasms 26%
  • Prostatic Neoplasms 21%
  • Castration 15%
  • Androgen Receptors 14%

• 探討利用類黃酮作為新穎DYRK1B抑制劑在惡性胰臟癌之療效

  HuangFu, W.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以深度學習預測抗糖尿病胜肽之免疫生物資訊學研究

  Su, E. C.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Fragment-Based Discovery of First-In-Class Small-Molecule Kinase Inhibitors for Targeted Cancer Therapies(2/2)

  Huang, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Crowdhealth Project: Using Health-Related Big Data for Supporting Policy Making Decisions

  Shabbir, S. A.

  4/1/19 → 3/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Crowdhealth Project: Using Health-Related Big Data for Supporting Policy Making Decisions 全文電子檔： [全文下載1]

  Shabbir, S. A.

  4/1/18 → 3/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 運用機器學習演算法透過基因體資訊挖掘未知基因的功能與預測細菌抗藥性(2/3)

  Wu, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Development and Preclinical Evaluation of a Theronostic Nanovehicle Drug for Treating Acute Myeloid Leukemia and Leukemia Stem Cells.( III )

  Yen, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Identification of Rewired APC Mutation Signaling Network in Chemotherapy Resistant Response in Colorectal Cancer (I)

  Huang, T.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adenomatous Polyposis Coli 100%
  • Colorectal Neoplasms 44%
  • Mutation 34%
  • Drug Resistance 28%
  • Fluorouracil 17%

• To Study the Role of Sp1 in Cancer Drug Resistance(3/3)

  Chuang, J.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Roles of microRNA96 in TGF-beta-Mediated Tumor Progression(2/3)

  Tsai, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Transforming Growth Factors 100%
  • Neoplasms 26%
  • Prostatic Neoplasms 21%
  • Castration 15%
  • Androgen Receptors 14%

• Investigation of the Cytotoxic Mechanism of Photorhabdus Luminescens Pirapl and Pirbpl Toxins by Using Structural and Proteomic Approaches

  Wang, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Photorhabdus 100%
  • Insecta 30%
  • Aedes 24%
  • toxin V 19%
  • Xenorhabdus 17%

• Smokefreebrain: Multidisciplinary Tools for Improving the Efficacy of Public Prevention Measures against Smoking

  Shabbir, S. A.

  5/1/18 → 4/30/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討胺基酸代謝基因標誌及其在雌激素高表達乳癌病人之治療機制(2/2)

  Wang, C.

  1/1/21 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Novel Long Non-Coding Rna as a Key Regulator of Tumor Metabolism(3/3)

  Kung, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pyruvate Kinase 100%
  • Long Noncoding RNA 75%
  • Prostatic Neoplasms 24%
  • Pyruvic Acid 16%
  • Taiwan 15%

• 建立新興環境汙染物與藥物毒理預測平台之研究

  Hsu, K.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of Context Aware Knowledge Supporting Systems---A Case Study of Premature Neonates Care

  Liu, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Functional Study of a Novel Long Non-Coding Rna Linat in Colorectal Cancer Progression

  Chen, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Pharmacological Role of a Novel Dyrk1a Inhibitor in Alzheimer'S Disease

  HuangFu, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Analyze the Risk Assessment of Cumulative Brain Concussion on Football Player Brain Lesions

  Lin, M.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Brain 100%
  • Sports 91%
  • Football 68%
  • Risk assessment 59%
  • Biomarkers 37%

• Role of Ribonucleotide Reductase (Rnr) in Skeletal Muscle with Age: the Functionality of Rrm2b in Repair and Regeneration

  Chen, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Skeletal Muscle 100%
  • Sarcopenia 58%
  • Regeneration 52%
  • Muscles 47%
  • Muscular Diseases 33%

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer

  Liu, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• Investigation of K63-Linked Deubiquitination Effects of Mcpip Family Members and Their Genetic Profiles through Tcga Data Analysis

  Liang, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • TNF Receptor-Associated Factor 2 100%
  • Ubiquitin 82%
  • Ubiquitination 71%
  • Genetic Profile 63%
  • Signal Transduction 38%

• 以基因剪輯技術(CRISPR/Cas9)應用於費城染色體為標靶之慢性骨髓性白血病治療

  Lee, C.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Therapeutic Role of Niemann-Pick Type C2 Protein in the Inhibition of Hscs Activation and Liver Fibrosis Treatment

  Liao, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Liver Cirrhosis 100%
  • Cholesterol 39%
  • Becaplermin 35%
  • Fibrosis 13%
  • Cell Proliferation 11%

• 以阿茲海默症模型細胞篩選與評估醣苷神經鞘醯胺衍生物之藥效

  Lin, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer(3/3)

  Liu, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• 以NIADS優化TNBC藥物篩檢平台並以基因編輯技術探討IL6R及IL7R在乳癌轉移所扮演的角色

  Lee, C.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Mechanisms of Histamine N-Methyltransferase (Hnmt)-Mediated Herceptinr Drug-Resistance in Breast Cancer Cells(3/3)

  Ho, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Trastuzumab 89%
  • Breast Neoplasms 16%
  • Tissue Array Analysis 9%
  • Gene Expression Profiling 8%

• Studies on the Mechanisms of Histamine N-Methyl-Transferase (Hnmt) as a Novel Molecular Marker to Help Clinician for Identifying of Herceptin Responder in Breast Cancer Patients(1/3)

  Ho, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Emerging Impact of Mbnl1-Celf1 Regulatory Circuit Involved in the Development of White Adipocyte, Inducible Brown Adipocytes, and Classical Brown Adipocyte through Post-Transcriptional Regulation.

  Lin, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Artificial Intelligence for Earlier and Safer Medicine Worldwide(2/4)

  Li, Y.

  1/1/19 → 10/8/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以單點基因編輯(single base editing)作為KRAS基因突變校正之抗癌治療研究

  Lee, C.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 嵌合抗原受體T細胞用於治療人類卵巢癌的免疫療法(2/3)

  Liu, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Prediction of Cancer Metastasis Using SVM-Based Model with Quantification of Pathway Changes between Different Disease Statuses

  Chiu, H. & Chang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Support vector machines 100%
  • Gene expression 91%
  • Oncology 55%
  • Proteomics 55%
  • Genomics 43%

• 探討HIV-1反轉錄酉每與新穎先導藥物之複合體結構以利優化作為抗HIV候選藥物

  Liu, C.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Building a Cancer Progress Model Based on PPI Network and Gene Expression Changes and Its Applications for Classification of Cancer Subtypes

  Chiu, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Gene expression 100%
  • Tumors 46%
  • Proteins 27%
  • Bioinformatics 16%
  • Brain 12%

• The Emerging Role That Splicing Factor Plays in the Adipose Development

  Lin, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • brown adipose tissue 100%
  • adipose tissue 84%
  • insulin receptors 78%
  • adipogenesis 75%
  • energy 49%

• Activation Autophagy by the Combination of a Histone Deacetylase Inhibitor and Radiation Limits BNIP3 Regulation in Triple-Negative Breast Cancer Cells and Orthotopic Mouse Model

  Chiu, H. & Ho, Y.

  8/1/15 → 6/30/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Triple Negative Breast Neoplasms 100%
  • Histone Deacetylase Inhibitors 97%
  • Ionizing Radiation 42%
  • Autophagy 39%
  • human ERBB2 protein 25%