College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2023

• 90 Active
• 914 Finished

Projects per year

Search results

• Establish the Research Platform for Studying Triple-Negative Breast Tumor Microenvironment Regulation---The Hyaluronan Synthase-3 Mediated Antitumor Effects as an Example

  Ho, Y. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Gene Expression 46%
  • Tumor Microenvironment 40%
  • Hyaluronan Synthases 30%
  • Fibroblasts 29%

• Establish the Research Platform for Studying Triple-Negative Breast Tumor Microenvironment Regulation: the Hyaluronan Synthase-3 Mediated Antitumor Effects as an Example.

  Ho, Y. & Wu, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Gene Expression 46%
  • Tumor Microenvironment 40%
  • Hyaluronan Synthases 30%
  • Fibroblasts 29%

• Establishing the Hub for “Learning Health System” for South Asia

  Li, Y.

  12/26/16 → 8/25/17

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Healthcare 100%
  • health 68%
  • information technology 30%
  • learning 29%
  • medical technology 26%

• Establishing the Disease and Genetic Risk Prediction Score of Cognitive Impairment to Early Prevent the Threat of Dementia

  Hsieh, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Dementia 100%
  • Neurodegenerative Diseases 80%
  • Iron-Deficiency Anemias 78%
  • Taiwan 65%
  • Cognitive Dysfunction 65%

• Ephs與Netrin受體在脊髓運動神經中的互動機制

  Kao, T.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › q - Cathay General Hospital

• Ephs與ephrins的多種相互作用，對脊髓運動神經的軸突引導所扮演的角色

  Kao, T.

  3/1/14 → 2/28/15

  Project: C - Project of Alliance › q - Cathay General Hospital

• Ephexin-1在脊髓運動神經的軸突引導中所扮演的角色

  Kao, T.

  3/1/15 → 2/29/16

  Project: C - Project of Alliance › q - Cathay General Hospital

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer(3/3)

  Liu, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer

  Liu, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer

  Liu, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• Emergency Medical Services Resource Management and Decesion Support Model for Intelligent Dispatch

  Hsu, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Patient treatment 100%
  • Accidents 52%
  • Mathematical models 45%
  • Communication 32%

• Emergency Medical Services Resource Management and Decesion Support Model for Intelligent Dispatch

  Hsu, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Patient treatment 100%
  • Accidents 52%
  • Mathematical models 45%
  • Communication 32%

• Elucidation of the Molecular Mechnism of Aglaia Elliptifolia Extract Rocaglamide Induced Cell Death in Breast Cancer Cells---PHB as a Target

  Huang, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Rocaglamide 100%
  • Oncogenic 11%
  • Cell Death 8%

• Effects of Central Neuromodulation with Functional Electrical Stimulation on Bladder Functions in Traumatic Brain Injured Rats

  Peng, C., Chen, S. & Hsieh, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Deep Brain Stimulation 100%
  • Traumatic Brain Injury 76%
  • Brain 29%
  • Urinary Bladder 27%
  • Urination 19%

• Effect of RRM2 in Tumor Metastasis and Chemotherapy Response of Colorectal Cancer Patients with Different APC and K-Ras Status

  Cheng, Y.

  8/1/14 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

  • Colorectal Neoplasms 100%
  • Drug Resistance 38%
  • ras Genes 37%
  • Taiwan 31%
  • Neoplasm Metastasis 25%

• Effect of RRM2 in Tumor Metastasis and Chemotherapy Response of Colorectal Cancer Patients with Different APC and K-Ras Status

  Cheng, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colorectal Neoplasms 100%
  • Drug Resistance 38%
  • ras Genes 37%
  • Taiwan 31%
  • Neoplasm Metastasis 25%

• Effect of Hmga2 in Chemotherapy Response of Colorectal Cancer Patients with Different Apc Status( III )

  Yen, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effect of HMGA2 in Chemotherapy Response of Colorectal Cancer Patients with Different APC Status (II)

  Yen, Y., Cheng, Y. & Wei, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• EBP1蛋白質對於細胞及病毒IRES的影響及其作用機轉

  Lin, J.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Dysregulation of Huntingtin-Associated Protein-Mediated Calcium Trafficking in Neurodegenerative Diseases

  Lin, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Proto-Oncogene Proteins c-bcr 100%
  • Proteins 89%
  • Huntingtin Protein 71%
  • Neurodegenerative Diseases 63%
  • Kinesin 62%

• Drug Discovery and Pharmacological Study of Novel pan-HDAC Inhibitors as Anti-Angiogenic Drugs

  Pan, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylase Inhibitors 100%
  • Histone Deacetylases 36%
  • Drug Discovery 23%
  • 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 18%
  • Animal Models 16%

• Drug Discovery and Pharmacological Study of Novel pan-HDAC Inhibitors as Anti-Angiogenic Drugs

  Pan, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylase Inhibitors 100%
  • Histone Deacetylases 36%
  • Drug Discovery 23%
  • 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 18%
  • Animal Models 16%

• Drug Discovery and Pharmacological Investigation of Selective Hdac1 and 2 Inhibitors as Novel Anticancer Drugs

  Pan, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone 100%
  • Antitumor 34%
  • Antineoplastic Agent 33%
  • Drug 29%
  • DNA Sequence 19%

• Drug Discovery and Pharmacological Investigation of Novel Selective Hdac Inhibitors as Anticancer Drugs(1/3)

  Pan, S.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Drug Discovery and Pharmacological Investigation of Novel Selective Hdac Inhibitors as Anticancer Drugs

  Pan, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Distribution of the Number of False Discoveries in Genome-Wide Linkage Scan

  Wang, W.

  8/1/13 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Genome 100%
  • Linkage 87%
  • Linkage Analysis 79%
  • False Discovery Rate 58%
  • False 33%

• Dissolution rate improvement of active pharmaceutical ingredients using supercritical fluid technology

  Sheu, M. & Liu, J.

  1/1/14 → 12/31/14

  Project: C - Project of Alliance › j - National Taipei University of Technology

• Dissection of Synergistic Involvement among Different Guidance Families in Spinal Motor Neuron Development

  Kao, T.

  12/1/13 → 11/30/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Motor Neurons 97%
  • Netrin-1 88%
  • Netrin Receptors 74%
  • Axons 68%
  • Growth Cones 57%

• Dissection of Synergistic Involvement among Different Guidance Families in Spinal Motor Neuron Development

  Kao, T.

  12/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Motor Neurons 97%
  • Netrin-1 88%
  • Netrin Receptors 74%
  • Axons 68%
  • Growth Cones 57%

• Disease trajectories and its association with metabolic dysfunction of prostate cancer men following androgen deprivation therapy and the potential of pharmacological medication in preventing metastatic diseases.(2/3)

  Shao, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Androgens 100%
  • Prostatic Neoplasms 60%
  • Hyperlipidemias 44%
  • Taiwan 43%
  • Metabolic Syndrome 30%

• Disease Trajectories and Its Association with Metabolic Dysfunction of Prostate Cancer Men Following Androgen Deprivation Therapy and the Potential of Pharmacological Medication in Preventing Metastatic Diseases.

  Shao, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Disease Trajectories and Its Association with Metabolic Dysfunction of Prostate Cancer Men Following Androgen Deprivation Therapy and the Potential of Pharmacological Medication in Preventing Metastatic Diseases.

  Shao, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Discovery of Selective Inhibitors for Oncoprotein Kinases

  Hsu, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Protein Kinases 100%
  • Phosphotransferases 92%
  • Oncogene Proteins 72%
  • Pharmaceutical Preparations 35%
  • Neoplasms 24%

• Discovery of multitarget inhibitors for colorectal cancer treatment using Pharmalogs

  Hsu, K. & Cheng, Y.

  2/1/16 → 1/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Discovery and Design of Kinase Inhibitors for Cancer Treatment

  Hsu, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Drug 100%
  • 50 Percent Growth Inhibition 63%
  • Disorder 40%
  • Protein 39%
  • Oncogenic 33%

• Development of Smart Peptide-based Therapeutic System for Coronary Ischemia

  Cheng, T.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Trastuzumab 88%
  • Neoplastic Stem Cells 39%
  • Drug Resistance 27%
  • Luciferases 20%

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C. & Ho, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Trastuzumab 88%
  • Neoplastic Stem Cells 39%
  • Drug Resistance 27%
  • Luciferases 20%

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Novel Therapeutic Agents for Breast Cancer through Targeting Nicotinic Acetylcholine Receptors.

  Wu, C., Ho, Y. & Lee, C.

  5/1/12 → 4/30/13

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Resistance 100%
  • Nicotine 97%
  • Acute Toxicity 95%
  • Acetylcholine 85%
  • Drug 83%

• Development of Novel Therapeutic Agents for Breast Cancer through Targeting Nicotinic Acetylcholine Receptors.

  Wu, C., Ho, Y. & Lee, C.

  5/1/14 → 7/30/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Resistance 100%
  • Nicotine 97%
  • Acute Toxicity 95%
  • Acetylcholine 85%
  • Drug 83%

• Development of Novel Therapeutic Agents for Breast Cancer through Targeting Nicotinic Acetylcholine Receptors.

  Wu, C., Ho, Y. & Lee, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Resistance 100%
  • Nicotine 97%
  • Acute Toxicity 95%
  • Acetylcholine 85%
  • Drug 83%

• Development of Novel Tetracyclic and Heterocyclic Dual Topoisomerases Inhibitors as Anticancer Agents( II )

  Huang, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Novel Tetracyclic and Heterocyclic Dual Topoisomerases Inhibitors as Anticancer Agents( I )

  Huang, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Topoisomerase Inhibitor 100%
  • Antineoplastic Agent 79%
  • Molecule 51%
  • Compound Mobility 45%
  • Anthraquinone 32%

• Development of Novel Dyrk1a Inhibitors for the Treatment of Alzheimer'S Disease

  HuangFu, W.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Dyrk kinase 100%
  • Alzheimer Disease 43%
  • Neurofibrillary Tangles 17%
  • Amyloid beta-Peptides 15%
  • Memory 10%

• Development of Novel Colchicine Derivative for Anticancer

  Liu, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colchicine 100%
  • Lethal Dose 14%
  • Drug 10%
  • Safety 8%
  • Food 6%

• Development of Noninvasive Blood Pressure Estimation with Photoplethysmography

  Chiu, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Photoplethysmography 100%
  • Blood pressure 82%
  • Wearable technology 21%
  • Neural networks 19%
  • Intensive care units 8%

• Development of Cortical Electrical Stimulation Technique for Improving Neuroplasticity and Motor Function in Parkinsonian Rats

  Hsieh, T., Chiang, Y. & Peng, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Cortical Electrical Stimulation Technique for Improving Neuroplasticity and Motor Function in Parkinsonian Rats

  Hsieh, T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electric Stimulation 100%
  • Parkinson Disease 98%
  • Neuronal Plasticity 24%
  • Oxidopamine 19%
  • Therapeutics 13%

• Development of a Computerized Adaptive Testing of the Health Literacy in Stroke Rehabilitation.

  Hou, W. & Chen, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Health Literacy 100%
  • Stroke Rehabilitation 86%
  • Psychometrics 23%
  • Stroke 21%
  • Rehabilitation 19%