College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022

• 110 Active
• 862 Finished

Projects per year

Search results

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer

  Liu, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer

  Liu, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer(3/3)

  Liu, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• Ephexin-1在脊髓運動神經的軸突引導中所扮演的角色

  Kao, T.

  3/1/15 → 2/29/16

  Project: C - Project of Alliance › q - Cathay General Hospital

• Ephs與ephrins的多種相互作用，對脊髓運動神經的軸突引導所扮演的角色

  Kao, T.

  3/1/14 → 2/28/15

  Project: C - Project of Alliance › q - Cathay General Hospital

• Ephs與Netrin受體在脊髓運動神經中的互動機制

  Kao, T.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › q - Cathay General Hospital

• Establishing the Disease and Genetic Risk Prediction Score of Cognitive Impairment to Early Prevent the Threat of Dementia

  Hsieh, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Dementia 100%
  • Neurodegenerative Diseases 80%
  • Iron-Deficiency Anemias 78%
  • Taiwan 65%
  • Cognitive Dysfunction 65%

• Establishing the Hub for “Learning Health System” for South Asia

  Li, Y.

  12/26/16 → 8/25/17

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Healthcare 100%
  • health 68%
  • information technology 30%
  • learning 29%
  • medical technology 26%

• Establish the Research Platform for Studying Triple-Negative Breast Tumor Microenvironment Regulation: the Hyaluronan Synthase-3 Mediated Antitumor Effects as an Example.

  Ho, Y. & Wu, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Gene Expression 46%
  • Tumor Microenvironment 40%
  • Hyaluronan Synthases 30%
  • Fibroblasts 29%

• Establish the Research Platform for Studying Triple-Negative Breast Tumor Microenvironment Regulation---The Hyaluronan Synthase-3 Mediated Antitumor Effects as an Example

  Ho, Y. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Gene Expression 46%
  • Tumor Microenvironment 40%
  • Hyaluronan Synthases 30%
  • Fibroblasts 29%

• ETFDH突變於阿茲海默症之類澱粉前驅蛋白生成和細胞焦亡扮演的角色

  Kao, S.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Evaluate and Engineer Anti-Fibroblast Growth Factor Receptor 2 (Fgfr2) Antibody Drugs and Study on Their Potential Application against Cancer

  Lee, Y.

  4/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibroblast Growth Factor Receptors 100%
  • Stomach Neoplasms 23%
  • Antibodies 21%
  • Receptor, Fibroblast Growth Factor, Type 2 16%
  • Neoplasms 16%

• Evaluation of an Early Detection Flu Information System

  Lo, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Information Systems 100%
  • Epidemics 78%
  • Taiwan 67%
  • Human Influenza 62%
  • Disease Outbreaks 60%

• Evaluation of Haptoglobin and Its Subunits as Protein Drugs for Ischemic Heart Diseases

  Cheng, T. & Shih, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Myocardial Ischemia 100%
  • Nanocapsules 63%
  • Pharmaceutical Preparations 40%
  • Haptoglobins 35%
  • Hemoglobins 34%

• Evolution Haptoglobins as Protein Drugs for Coronary Artery Diseas

  Cheng, T.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Haptoglobins 100%
  • Coronary Artery Disease 52%
  • Inflammation 27%
  • Nanoparticles 20%
  • Monocytes 19%

• Exploration and Investigation of Brown Adipogenesis-Associated Alternative Splicing Network by Transcriptome Analyses

  Lin, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • brown adipose tissue 100%
  • adipogenesis 64%
  • alternative splicing 41%
  • brown adipocytes 34%
  • obesity 25%

• Exploration of RBM4-Regulated Splicing Events in Differentiating Adipocytes by Using Next-Generation Sequencing

  Lin, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • brown adipose tissue 100%
  • insulin receptors 70%
  • adipocytes 54%
  • adipose tissue 50%
  • adipogenesis 45%

• Exploration of RBM4-Regulated Splicing Events in Differentiating Adipocytes by Using Next-Generation Sequencing

  Lin, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • brown adipose tissue 100%
  • insulin receptors 70%
  • adipocytes 54%
  • adipose tissue 50%
  • adipogenesis 45%

• Exploration of the Pathogenesis of Acute Hepatopancreatic Necrosis Disease (Ahpnd) in Shrimp(3/3)

  Wang, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Exploring Biopathways Related to Cancer Based on Differences of Gene Expression between Cancer and Normal Situation

  Chiu, H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Proteins 100%
  • Gene expression 99%
  • Proteomics 48%
  • Genomics 37%

• Exploring the Potential Applications of Dna Mimic Protein Saugi in Viral Diseases and Mrsa by Structure-Based Study

  Wang, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Uracil-DNA Glycosidase 100%
  • Simplexvirus 47%
  • Staphylococcus aureus 37%
  • vpr Gene Products 35%
  • Human Immunodeficiency Virus Proteins 29%

• "First-in-Class"新穎性抗癌藥物ITCH E3 ubiquitinligase 抑制劑之新藥開發

  Yen, Y.

  7/1/17 → 6/30/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Fragment-Based Discovery of First-In-Class Small-Molecule Kinase Inhibitors for Targeted Cancer Therapies(2/2)

  Huang, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Fragment-Based Discovery of First-In-Class Small-Molecule Kinase Inhibitors for Targeted Cancer Therapies( I )( I )

  Huang, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphotransferase Inhibitor 100%
  • Antineoplastic Agent 52%
  • Drug 31%
  • Molecule 27%
  • Chemistry 23%

• Functional Characterization of Niemann-Pick Type C2 Protein in Hepatocellular Carcinoma

  Liao, Y.

  1/1/13 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Liver Neoplasms 46%
  • Cholesterol 45%
  • Mitogen-Activated Protein Kinase 1 34%
  • Liver 32%

• Functional Characterization of Niemann-Pick Type C2 Protein in Hepatocellular Carcinoma

  Liao, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Liver Neoplasms 46%
  • Cholesterol 45%
  • Mitogen-Activated Protein Kinase 1 34%
  • Liver 32%

• Functional Evaluation of Extracts and Pure Compounds Isolated from VI Tis Thunbergii Var. Taiwaniana on the Improvements of Metabolic Syndrome-Related Diseases

  Hou, W., Liu, D. & Liang, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Vitis ficifolia 100%
  • metabolic syndrome 58%
  • diabetes 45%
  • extracts 33%
  • cardiovascular diseases 23%

• Functional Outcomes and Cognitive Interventions in Older People following Traumatic Brain Injury

  Lin, M., Tsai, S., Chen, S., Chiang, Y., Liou, T., Lin, Y. & Shu Kei Lam, C.

  1/1/15 → 12/31/15

  Project: A - Government Institution › a - National Health Research Institutes

  • Traumatic Brain Injury 100%
  • Tai Ji 13%
  • Brain Death 11%
  • Executive Function 9%
  • Activities of Daily Living 9%

• Functional Outcomes and Cognitive Interventions in Older People following Traumatic Brain Injury

  Lin, M., Tsai, S., Chen, S., Chiang, Y., Liou, T., Lin, Y. & Shu Kei Lam, C.

  1/1/14 → 12/31/14

  Project: A - Government Institution › a - National Health Research Institutes

  • Traumatic Brain Injury 100%
  • Tai Ji 13%
  • Brain Death 11%
  • Executive Function 9%
  • Activities of Daily Living 9%

• Functional Outcomes and Cognitive Interventions in Older People following Traumatic Brain Injury

  Lin, M., Tsai, S., Chen, S., Chiang, Y., Liou, T., Lin, Y. & Shu Kei Lam, C.

  1/1/16 → 12/31/16

  Project: A - Government Institution › a - National Health Research Institutes

  • Traumatic Brain Injury 100%
  • Tai Ji 13%
  • Brain Death 11%
  • Executive Function 9%
  • Activities of Daily Living 9%

• Functional Study of a Novel Long Non-Coding Rna Linat in Colorectal Cancer Progression

  Chen, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Functional Study of a Novel Long Non-Coding Rna Linat in Colorectal Cancer Progression

  Chen, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Functional Study of a Novel Long Non-Coding Rna Linat in Colorectal Cancer Progression(2/3)

  Chen, H.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Gene Knock out Mice Model for Studying the Molecular Mechanisms of Early Onset Breast Tumor Microenvironment Regulation.

  Wu, C., Ho, Y. & Tu, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • breast 100%
  • cancer 97%
  • tumors 59%
  • fibroblasts 33%
  • genes 31%

• Generate Anti-Erythropoietin Producing Hepatocellular Receptor Type-A2 (Epha2) Antibody Drugs and Study on Their Potential Application against Pancreatic Cancer

  Lee, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Generate anti-Fibroblast growth factor receptor 2 (FGFR2) antibody drugs and study on their potential application against gastric cancer

  Lee, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Generate Anti-Fibroblast Growth Factor Receptor 2 (Fgfr2) Antibody Drugs and Study on Their Potential Application against Gastric Cancer

  Lee, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Generate Anti-Fibroblast Growth Factor Receptor 2 (Fgfr2) Antibody Drugs and Study on Their Potential Application against Gastric Cancer

  Lee, Y.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Gene Signatures and Potential Therapeutic Targets of Amino Acid Metabolism in Estrogen Receptor-Positive Breast Cancer(1/2)

  Wang, C.

  1/1/20 → 12/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Anoikis 60%
  • Breast Neoplasms 60%
  • Amino Acids 58%
  • TOR Serine-Threonine Kinases 34%
  • tamoxifen acid 21%

• Genetic Polymorphisms in Hypoxia Inducible Factor-1 and Inflammation Pathway Related microRNA and Its Target Genes and Risk of Hyperglycemia in Acute Ischemic Stroke and Its Prognosis Study

  Hsieh, Y., Cho, E., Chi, N. & Chiou, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Hyperglycemia 79%
  • Stroke 64%
  • Inflammation 37%
  • Biomarkers 10%

• Genetic Polymorphisms in microRNA and Risk of the Post-Thrombolytic Hyperglycemia in Acute Ischemic Stroke and Its Prognosis Study

  Hsieh, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hyperglycemia 100%
  • MicroRNAs 92%
  • Stroke 80%
  • Single Nucleotide Polymorphism 42%
  • Small Untranslated RNA 10%

• Genomic, Epigenomic and Epiproteomic Analysis of Etk/Bmx Traumatic Brain Injury

  Chen, K., Chiang, Y. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Protein Kinases 15%
  • Epigenomics 14%
  • Tec protein-tyrosine kinase 14%
  • Inflammation Mediators 10%

• Germline Dna Repair Gene Mutations in Advanced Prostate Cancer

  Shao, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• G蛋白偶聯雌激素受體在EGFR突變之肺腺癌細胞中扮演的角色

  Kao, S.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• HDAC6 藉由稳定膠質母细胞瘤中的雄激素受體表達來調節RAD51促進治療抗藥性發展

  Chuang, J.

  1/1/20 → 12/31/20

  Project: A - Government Institution › d - Ministry of Education

• Health Internet of Things (Hiot) Medicine, Research &Amp; Industry( I )

  Li, Y.

  2/1/17 → 1/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Internet of things 100%
  • Industry 52%
  • Clinical research 33%
  • Wearable technology 26%
  • Data Analytics 26%

• Helmet Use, Return to Work, and Health-Related Quality of Life among Motorcycle Riders with Head Injury

  Lin, M., Chiu, W. & Chiang, Y.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • motorcycles 100%
  • health care workers 61%
  • health services 33%
  • quality-adjusted life year 28%
  • social change 22%

• Hmga2, a New Target of Thyroid Hormone-Induced Progression in Colorectal Cancers

  Lin, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • Thyroid Hormones 82%
  • tetraiodothyroacetic acid 76%
  • Colorectal Neoplasms 47%
  • Integrins 31%

• HMGA2, a New Target of Thyroid Hormone-Induced Progression in Colorectal Cancers

  Lin, H., Chang, T. & Yen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • Thyroid Hormones 75%
  • tetraiodothyroacetic acid 70%
  • Colorectal Neoplasms 43%
  • Integrins 28%

• HMGA2, a New Target of Thyroid Hormone-Induced Progression in Colorectal Cancers(2/3)

  Lin, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • Thyroid Hormones 75%
  • tetraiodothyroacetic acid 70%
  • Colorectal Neoplasms 43%
  • Integrins 28%