College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2024

• 72 Active
• 1019 Finished

Projects per year

Search results

• Finished

  Neuroprotective Effects of Sig-1R-Znf179-Sp1 Pathway on Brain Injury

  Chang, W. & Chuang, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • sigma-1 receptor 100%
  • Traumatic Brain Injury 50%
  • Hydrogen Peroxide 31%
  • Neuroprotective Agents 19%
  • Wounds and Injuries 12%

• Design and Preclinical Translation Study of Mixed-Bispecific/Trispecific Antibody for Enhancing Therapeutic Effectiveness of Anticancer Drug-Loaded Pegylated Nanocarriers by Simultaneously Targeting to Tumor Cells and Cancer/Tumor Associated Fibrobla (I)

  Sheu, M., Chuang, K. & Ho, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Nanocarrier 100%
  • Antigen 77%
  • Tumor Marker 61%
  • Modification 51%
  • Liposome 42%

• Systemic Analysis on Dynamic Mechanism of Actin Cytoskeleton Organization Regulated Physiological Changes Caused by Physical Stimuli in Mesenchymal Stem Cells

  Ho, J. & Chang, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Actins 100%
  • Mesenchymal Stem Cells 72%
  • Proteins 24%
  • Polymerization 22%
  • Microfilament Proteins 19%

• Study of Expression and Functional Mechanisms of Histamine N-Methyltransferase (HNMT) in Tumorigenesis and Correlation with Progression in Lung Cancer

  Wang, L., Lee, W., Ho, Y. & Wu, A. T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Lung Neoplasms 43%
  • Carcinogenesis 18%
  • Neoplasms 10%
  • Genes 9%

• Prediction of Cancer Metastasis Using SVM-Based Model with Quantification of Pathway Changes between Different Disease Statuses

  Chiu, H. & Chang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Support vector machines 100%
  • Gene expression 91%
  • Oncology 55%
  • Proteomics 55%
  • Genomics 43%

• Molecular Ivestigation of the Electron Transfer Flavoprotein Dehydrogenase Mutation Induced Mitochondrial Dysfunction and Metabolic Defects

  Kao, S. & Hsu, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • acyl-CoA dehydrogenase 100%
  • flavoproteins 97%
  • electron transfer 79%
  • droplets 39%
  • myoblasts 31%

• Evaluation of Haptoglobin and Its Subunits as Protein Drugs for Ischemic Heart Diseases

  Cheng, T. & Shih, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Myocardial Ischemia 100%
  • Nanocapsules 63%
  • Pharmaceutical Preparations 40%
  • Haptoglobins 35%
  • Hemoglobins 34%

• Study a Novel Klf10 (Kruppel-Like Transcription Factor10) Regulated Mechanism in Non-Alcoholic Fatty Liver Disease (NAFLD)

  Chang, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Non-alcoholic Fatty Liver Disease 100%
  • AMP-Activated Protein Kinases 80%
  • Sterol Regulatory Element Binding Protein 1 57%
  • Lipid Metabolism 32%
  • Type 2 Diabetes Mellitus 19%

• Crystal Structures and Functional Studies of Novel Glycosyltransferases from Staphylococcus aureus

  Liu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycosyltransferases 100%
  • Staphylococcus aureus 64%
  • Fibrin 30%
  • Cathepsin G 22%
  • Minisatellite Repeats 19%

• Investigate Pathogenic Role of Rheumatoid Arthritis, Sjogren's Syndrome, Systemic Lupus Erythematosus and Its Combined Syndromes from Post-Translational Modification of Novel Synovial Fluid and Serum Proteins---Study of 4-Hydroxy-2-Nonenal Modificatio

  Lin, C. & Chang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • rheumatoid arthritis 100%
  • lupus erythematosus 99%
  • autoantibodies 49%
  • proteins 31%
  • autoimmune diseases 29%

• Study of C3H-Type Zinc-Finger Proteins on the Down-Regulation of Ubiquitination-Mediated Activation of Signal Transduction

  Liang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Ubiquitin 100%
  • Ubiquitination 71%
  • Lysine 32%
  • Zinc Fingers 28%
  • Signal Transduction 25%

• The Role of Neuropilin-1 Glycosylation in Galectin-1 Induced Activation of Hepatic Stellate Cells and Liver Fibrosis

  Wu, M. & Yang, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Galectin 1 100%
  • Neuropilin-1 68%
  • Liver Cirrhosis 28%
  • Platelet-Derived Growth Factor Receptors 24%
  • thiodigalactoside 12%

• Analyses of ADAM9 on Integrin B4 Turnover to Facilitate Prostate Cancer Migration and Invasion

  Sung, S. & Hsieh, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • metastasis 100%
  • integrins 89%
  • neoplasm progression 42%
  • prostatic neoplasms 38%
  • neoplasms 38%

• Uncovering the Specific Interactions between DNA Mimic Proteins and Their Target DNA Binding Proteins by Structure-Based Studies

  Wang, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • DNA 100%
  • Uracil-DNA Glycosidase 61%
  • Proteins 58%
  • Neisseria 55%
  • DNA-Binding Proteins 44%

• Cocaine Induces Sig-1R Nuclear Envelope Localization to Regulate MAOB Expression by Interacting with Emerin-HDACs Co-Repressor Complex

  Chuang, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • sigma-1 receptor 100%
  • Cocaine 63%
  • Monoamine Oxidase 42%
  • emerin 30%
  • Co-Repressor Proteins 29%

• 子宮內膜異位症體外血清診斷試劑開發計畫(1/2)

  Yang, W.

  8/1/15 → 3/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigate the Biological and Prognostic Association of Annexin A2 in Nasopharyngeal Carcinoma

  Chen, C. & Lee, F.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Annexin A2 100%
  • Nasopharyngeal Carcinoma 85%
  • Annexins 40%
  • DC-specific ICAM-3 grabbing nonintegrin 12%
  • Radiotherapy 10%

• The Role of Wnt5a and Hsp90 in the Wnt/Beta-Catenin Signaling Pathway of Colorectal Cancer (II)

  Lee, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effect of Long Acting GnRH Agonist Treatment on Mitochondrial Function

  Tzeng, C., Hsieh, R. & Kao, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • hormone agonists 100%
  • mitochondria 91%
  • pathophysiology 42%
  • granulosa cells 38%
  • agonists 32%

• The Role of EGFR in Prostate Cancer Progression and Combination Therapy

  Liu, Y. & Chen, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • ErbB Receptors 82%
  • Berberis 26%
  • Neoplastic Stem Cells 16%
  • Neoplasms 15%

• Using Automatic Facial Expression Analysis as a Tool to Long Term Evaluation in Fibromyalgia Patients

  Kang, J., Lee, H. & Yeh, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibromyalgia 100%
  • Systems Analysis 42%
  • Cell Phone 34%
  • Facial Expression 33%
  • Clinical Psychology 12%

• The Study of Therapeutic Effects for Stroke with Phenserine, an Amyloid Precursor Protein Inhibitor, in Rodent Focal Cerebral Ischemia Model

  Chang, C. & Chiang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • phenserine 100%
  • Stroke 75%
  • Amyloid beta-Protein Precursor 49%
  • Stem Cells 31%
  • pifithrin 27%

• Genomic, Epigenomic and Epiproteomic Analysis of Etk/Bmx Traumatic Brain Injury

  Chen, K., Chiang, Y. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Protein Kinases 15%
  • Epigenomics 14%
  • Tec protein-tyrosine kinase 14%
  • Inflammation Mediators 10%

• Activation Autophagy by the Combination of a Histone Deacetylase Inhibitor and Radiation Limits BNIP3 Regulation in Triple-Negative Breast Cancer Cells and Orthotopic Mouse Model

  Chiu, H. & Ho, Y.

  8/1/15 → 6/30/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Triple Negative Breast Neoplasms 100%
  • Histone Deacetylase Inhibitors 97%
  • Ionizing Radiation 42%
  • Autophagy 39%
  • human ERBB2 protein 25%

• Identification of Rewired APC Mutation Signaling Network in Chemotherapy Resistant Response in Colorectal Cancer (II)

  Huang, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C. & Ho, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Trastuzumab 88%
  • Neoplastic Stem Cells 39%
  • Drug Resistance 27%
  • Luciferases 20%

• Development of a Computerized Adaptive Testing of the Health Literacy in Stroke Rehabilitation.

  Hou, W. & Chen, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Health Literacy 100%
  • Stroke Rehabilitation 86%
  • Psychometrics 23%
  • Stroke 21%
  • Rehabilitation 19%

• Development of Novel Therapeutic Agents for Breast Cancer through Targeting Nicotinic Acetylcholine Receptors.

  Wu, C., Ho, Y. & Lee, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Resistance 100%
  • Nicotine 97%
  • Acute Toxicity 95%
  • Acetylcholine 85%
  • Drug 83%

• To See Is to Believe- Visualization of the Spectrum on Chronic Kidney Disease (II)

  Jian, W., Li, Y. & Wu, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Health care 100%
  • Data visualization 75%
  • Patient treatment 50%
  • Disease control 49%
  • Health insurance 49%

• To enhance the day care center service quality and safety surveillance by using information and communications technology

  Jian, W., Shabbir, S. A. & Lin, C.

  7/8/15 → 3/7/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Health care 100%
  • Aging of materials 52%
  • Communication 49%
  • Monitoring 37%
  • Medicine 33%

• 104年度「委託科技研究計畫--以資通訊科技提升照護品質」分項計畫5：長期照護服務導入資通訊科技之策略規劃

  Yen, Y., Chiou, H., Liu, C. & Lin, P.

  6/12/15 → 2/11/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Long-term Care 100%
  • System Development 22%
  • Needs Assessment 18%
  • Taiwan 17%
  • Managers 16%

• 篩選一個具有保護神經而且可能發展為腦創傷治療藥物的Sigma 1受體促效劑

  Chuang, J.

  6/1/15 → 5/31/16

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 片段化TDP-43蛋白在缺血性腦中風之神經發炎物質NF-κB 訊息傳遞路徑中所扮演的角色

  Huang, C.

  6/1/15 → 5/31/16

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 探討integrin αvβ3及EGFR間交叉效應對於甲狀腺賀爾蒙誘發大腸直腸癌細胞增生作用之影響

  Lin, H.

  6/1/15 → 5/31/16

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 台灣小葉葡萄抽取物改善高血糖之體內與體外研究

  Liang, Y.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 臨床前FGFR抑制劑對於抗藥性胰臟癌療效之評估

  Wu, A. T.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 運用化學基因體學方法開發新穎核糖核?酸還原?抑制劑用以治療大腸直腸癌

  Yang, P.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• Metformin和atorvastatin的藥物組合以增強肺癌放射治療效果的探討

  Wu, M.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 鋅指蛋白質負向調控生長訊息分子活性之研究

  Liang, Y.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 從染色體中心節蛋白(CENP)家族中找尋可以用來當作卵巢癌的新腫瘤標的

  Lee, K.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 探討Androgen receptor調控WNT 訊號傳遞在攝護腺癌之作用機轉

  Liu, Y.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 建構領航國際之活躍老化監測暨決策支援系統-活躍老化資料倉儲與決策支援系統(104-107年)之需求規劃暨監造管理計畫

  Liu, C., Yeh, Y., Chiou, H. & Chi, M.

  4/30/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• TMU103-AE1-B26

  Lin, M.

  4/1/15 → 9/30/16

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Evaluate and Engineer Anti-Fibroblast Growth Factor Receptor 2 (Fgfr2) Antibody Drugs and Study on Their Potential Application against Cancer

  Lee, Y.

  4/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibroblast Growth Factor Receptors 100%
  • Stomach Neoplasms 22%
  • Antibodies 20%
  • Receptor, Fibroblast Growth Factor, Type 2 15%
  • Neoplasms 15%

• TMU103-AE1-B19

  Lee, Y.

  4/1/15 → 3/31/16

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• A cohort study of chronic kidney disease (the 101th-104th year of the Republic Era)

  Lin, Y., Chiou, H., Hsu, Y., Wu, M., Hsieh, F., Bai, C., Hsieh, Y., Chien, L., Wang, Y., Wu, M., Yang, S., Lin, Y. & Lin, C.

  3/31/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Chronic Renal Insufficiency 100%
  • Taiwan 77%
  • Chronic Kidney Failure 68%
  • Annual Reports 21%
  • Data Systems 19%

• Ephexin-1在脊髓運動神經的軸突引導中所扮演的角色

  Kao, T.

  3/1/15 → 2/29/16

  Project: C - Project of Alliance › q - Cathay General Hospital

• 探討腦指蛋白Rnf112的神經保護作用及機制

  Lee, Y.

  3/1/15 → 3/31/16

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• 應用穿戴科技於院內病人辨識

  Shabbir, S. A.

  3/1/15 → 3/31/16

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• 探討Annexin A2 在鼻咽癌的致癌功能與臨床應用

  Chen, C.

  3/1/15 → 2/29/16

  Project: C - Project of Alliance › o - Chi Mei Medical Center