College of Medical Science and Technology

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2024

• 73 Active
• 1019 Finished

Projects per year

Search results

• Development of Cortical Electrical Stimulation Technique for Improving Neuroplasticity and Motor Function in Parkinsonian Rats

  Hsieh, T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electric Stimulation 100%
  • Parkinson Disease 98%
  • Neuronal Plasticity 24%
  • Oxidopamine 19%
  • Therapeutics 13%

• Role of miR-21 in Regulating TET I-Hydroxymethylcytosine and Chemotherapeutic Response in Colorectal Cancer (I)

  Yang, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colorectal Neoplasms 100%
  • 5-hydroxymethylcytosine 84%
  • APC Genes 58%
  • DNA Methylation 55%
  • Adenomatous Polyposis Coli 51%

• Investigation of the Intrinsic Molecular Mechanisms of ETV6 That Contribute to Suppression of Metastasis and Sensitivity of Chemotherapy in Prostate Cancer

  Liu, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Prostatic Neoplasms 100%
  • Neoplasm Metastasis 28%
  • ras Genes 16%
  • Nuclear Receptor Co-Repressor 2 11%
  • Drug Therapy 11%

• 探討攝護腺癌轉移過程中調控WNT 訊號傳遞之miRNA的作用機轉

  Liu, Y.

  6/1/14 → 7/31/15

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 老年性聽力損失: Cisd2缺失會加速老化過程中的聽力損傷

  Chen, Y.

  11/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• https://www.grb.gov.tw/search/planDetail?id=8356932&docId=447412

  Lin, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Malondialdehyde 100%
  • Synovial Fluid 29%
  • Proteins 28%
  • Autoantibodies 17%
  • Rheumatoid Arthritis 15%

• Effect of RRM2 in Tumor Metastasis and Chemotherapy Response of Colorectal Cancer Patients with Different APC and K-Ras Status

  Cheng, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colorectal Neoplasms 100%
  • Drug Resistance 38%
  • ras Genes 37%
  • Taiwan 31%
  • Neoplasm Metastasis 25%

• A Preclinical and Clinical Trial Evaluation for an in vitro Diagnostic Kit of Endometriosis (II)

  Yang, W.

  12/1/13 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of the Oncogenic Role of Prohibitin in Breast Cancer Progression

  Huang, T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Oncogenic 100%
  • Rocaglamide 67%
  • Subcellular Localization 48%
  • Cell Viability 35%
  • Plasma 21%

• Prognosis Analysis and Data Mining for Emergency Patients after Arriving Hospital

  Hsu, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fires 100%
  • Health insurance 91%
  • Analytic hierarchy process 67%
  • Health care 61%
  • Data mining 50%

• Study the Therapeutic Role of Niemann-Pick Type C2 Protein in Liver Cancer

  Liao, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Liver Neoplasms 70%
  • Carcinogenesis 40%
  • Cholesterol 39%
  • Liver 36%

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Trastuzumab 88%
  • Neoplastic Stem Cells 39%
  • Drug Resistance 27%
  • Luciferases 20%

• Pre-Clinical and Clinical Study for Multi-Nation Intelligent Medication Safety System

  Li, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Decision support systems 100%
  • Security systems 98%
  • Health 71%
  • Automatic identification 58%
  • Health care 49%

• Dissection of Synergistic Involvement among Different Guidance Families in Spinal Motor Neuron Development

  Kao, T.

  12/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Motor Neurons 97%
  • Netrin-1 88%
  • Netrin Receptors 74%
  • Axons 68%
  • Growth Cones 57%

• Combination Treatment of Tetrac- and Cetuximab-Induced Anti-Proliferation in Colorectal Cancer with Different APC Status (I)

  Lin, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tetraiodothyroacetic acid 100%
  • Cetuximab 77%
  • Adenomatous Polyposis Coli 38%
  • Colorectal Neoplasms 28%
  • Integrins 16%

• The Study of Therapeutic Effects for Stroke with Phenserine, an Amyloid Precursor Protein Inhibitor, in Rodent Focal Cerebral Ischemia Model(2/3)

  Chang, C. & Chiang, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › a - National Health Research Institutes

  • phenserine 100%
  • Stroke 75%
  • Amyloid beta-Protein Precursor 49%
  • Stem Cells 31%
  • pifithrin 27%

• Drug Discovery and Pharmacological Study of Novel pan-HDAC Inhibitors as Anti-Angiogenic Drugs

  Pan, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylase Inhibitors 100%
  • Histone Deacetylases 36%
  • Drug Discovery 23%
  • 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 18%
  • Animal Models 16%

• Identification of Human Viral Micrornas and Its Targets by Using Small RNA Sequencing Data Based on RNA Sequence and Structure Features

  Chang, T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Forensic Anthropology 14%
  • Databases 13%
  • Viruses 7%
  • Mammals 6%

• The Mechanistic Action of DDX3 in Colorectal Tumor Progression

  Lee, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Catenins 100%
  • Drug Resistance 26%
  • Neoplasms 25%
  • Colorectal Neoplasms 22%
  • Carcinogenesis 22%

• The Roles of Novel CCCH Zinc Finger Genes on the Regulation of Cell Proliferation and Inflammation

  Liang, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pyroptosis 100%
  • Apoptosis 69%
  • Genes 65%
  • Inflammasomes 60%
  • Cell Proliferation 58%

• Translational Investigation for Tea Attenuate Smoking-Induced Disease---Breast Cancer and Atherosclerosis as a Mechanistic Study

  Ho, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Tea 100%
  • Nicotine 26%
  • Capsules 23%
  • Breast Neoplasms 23%
  • Smoking 19%

• Exploration of RBM4-Regulated Splicing Events in Differentiating Adipocytes by Using Next-Generation Sequencing

  Lin, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • brown adipose tissue 100%
  • insulin receptors 70%
  • adipocytes 54%
  • adipose tissue 50%
  • adipogenesis 45%

• Bone-Marrow-Derived Mesenchymal Stem Cells in Prostate Cancer-Induced Bone Remodeling

  Hsieh, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adipogenic 100%
  • Osteogenic 37%

• MicroRNA-184在肺腫瘤化和臨床預後之角色

  Lee, H.

  8/1/14 → 7/31/15

  Project: C - Project of Alliance › r - Tung's Taichung MetroHarbor Hospital

• Distribution of the Number of False Discoveries in Genome-Wide Linkage Scan

  Wang, W.

  8/1/13 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Genome 100%
  • Genome-Wide Association Study 51%
  • Technology 48%
  • High-Throughput Nucleotide Sequencing 47%
  • Statistics 37%

• Uncovering the Specific Interactions between DNA Mimic Proteins and Their Target DNA Binding Proteins by Structure-Based Studies

  Wang, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • DNA 100%
  • Uracil-DNA Glycosidase 61%
  • Proteins 58%
  • Neisseria 55%
  • DNA-Binding Proteins 44%

• TMU102-AE1-B27

  Chen, K.

  1/1/14 → 7/31/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Cocaine Induces Sig-1R Nuclear Envelope Localization to Regulate MAOB Expression by Interacting with Emerin-HDACs Co-Repressor Complex

  Chuang, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • sigma-1 receptor 100%
  • Cocaine 63%
  • Monoamine Oxidase 42%
  • emerin 30%
  • Co-Repressor Proteins 29%

• Dysregulation of Huntingtin-Associated Protein-Mediated Calcium Trafficking in Neurodegenerative Diseases

  Lin, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Proto-Oncogene Proteins c-bcr 100%
  • Proteins 89%
  • Huntingtin Protein 71%
  • Neurodegenerative Diseases 63%
  • Kinesin 62%

• The Role of Neuropilin-1 Glycosylation in Galectin-1 Induced Activation of Hepatic Stellate Cells and Liver Fibrosis

  Wu, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Galectin 1 100%
  • Neuropilin-1 68%
  • Liver Cirrhosis 28%
  • Platelet-Derived Growth Factor Receptors 24%
  • thiodigalactoside 12%

• Investigation on the Epigenetic Regulation of Autophagy

  Yang, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Autophagy 100%
  • Enhancer of Zeste Homolog 2 Protein 91%
  • GSK343 51%
  • Triple Negative Breast Neoplasms 41%
  • Epigenomics 21%

• Association between Human Endogenous Retrovirus and Cancers Using RNA-Seq Data

  Lee, Y. G.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Endogenous Retroviruses 100%
  • RNA-Seq 28%
  • Genome 22%
  • Neoplasms 21%
  • gag Genes 11%

• Establish the Research Platform for Studying Triple-Negative Breast Tumor Microenvironment Regulation: the Hyaluronan Synthase-3 Mediated Antitumor Effects as an Example.

  Ho, Y. & Wu, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Gene Expression 46%
  • Tumor Microenvironment 40%
  • Hyaluronan Synthases 30%
  • Fibroblasts 29%

• Building a Cancer Progress Model Based on PPI Network and Gene Expression Changes and Its Applications for Classification of Cancer Subtypes

  Chiu, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Gene expression 100%
  • Tumors 46%
  • Proteins 27%
  • Bioinformatics 16%
  • Brain 12%

• 探討小泛素蛋白Sentrin-specific protease 2 參與轉型生長因子-beta訊息傳遞的作用機制(2/2)

  Chang, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Wnt5a and Hsp90 in the Wnt/Beta-Catenin Signaling Pathway of Colorectal Cancer (I)

  Lee, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Catenins 100%
  • Wnt Signaling Pathway 71%
  • Colorectal Neoplasms 58%
  • Adenomatous Polyposis Coli 39%
  • 5-(2,4-dihydroxy-5-isopropylphenyl)-4-(4-morpholin-4-ylmethylphenyl)isoxazole-3-carboxylic acid ethylamide 19%

• Analyses of ADAM9 on Integrin b4 Turnover to Facilitate Prostate Cancer Migration and Invasion

  Sung, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • metastasis 100%
  • integrins 89%
  • neoplasm progression 42%
  • prostatic neoplasms 38%
  • neoplasms 38%

• Study of the Mechanism of HPV Involved Tumorigenesis through Wnt Signaling Pathway Related microRNA Regulation

  Cheng, Y. & Lee, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Catenins 100%
  • MicroRNAs 89%
  • Lung Neoplasms 52%
  • Carcinogenesis 50%
  • Lung 49%

• Structure-Based Design, Synthesis and Biological Evaluation of Novel 6-Substituted 10-Chloro-12h-Thiochromeno[2,3-C]Quinolin-12-One Derivatives as Potential Anticancer Agents

  Huang, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antineoplastic Agent 100%
  • Intoplicine 80%
  • Molecule 65%
  • Topoisomerase Inhibitor 63%
  • Growth Inhibition 44%

• 北區高階生醫產業聚落及產業規劃-台灣遠距健康產業聚落發展先導計畫

  Yen, Y. & Chen, R.

  9/1/14 → 8/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 探討HIV-1反轉錄酉每與新穎先導藥物之複合體結構以利優化作為抗HIV候選藥物

  Liu, C.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Identification of Rewired APC Mutation Signaling Network in Chemotherapy Resistant Response in Colorectal Cancer (I)

  Huang, T.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adenomatous Polyposis Coli 100%
  • Colorectal Neoplasms 44%
  • Mutation 34%
  • Drug Resistance 28%
  • Fluorouracil 17%

• An in Silico Vaccine Design Based on T-Cell Epitope Prediction

  Su, E. C.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epitopes 100%
  • T-cells 61%
  • Vaccines 35%
  • Antigens 27%
  • Physicochemical properties 19%

• Study and Implementation of Patient Privacy Protection under the Framework for Electronic Medical Records Exchange in Taiwan

  Liu, C.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electronic medical equipment 100%
  • Data privacy 38%
  • Health insurance 14%
  • Virtual private networks 13%
  • Law enforcement 10%

• Investigation of Host Factors Affecting the Pathogenesis of Enterovirus 71 in Neuron and Non-Returnable Cells

  Lin, J.

  12/1/14 → 11/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Enterovirus 100%
  • Enterovirus Infections 87%
  • Tropism 44%
  • Small Interfering RNA 31%
  • Taiwan 24%

• TMU102-AE1-B22

  Kao, T.

  1/1/14 → 12/31/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• The role of miR-203 and miR-34a in EGFR activation prostate cancer metastasis

  Liu, Y.

  1/1/15 → 12/31/15

  Project: A - Government Institution › a - National Health Research Institutes

  • ErbB Receptors 100%
  • Prostatic Neoplasms 30%
  • Neoplasm Metastasis 23%
  • Prostate 15%
  • Down-Regulation 13%

• A cohort study of chronic kidney disease (the 101th-104th year of the Republic Era)

  Lin, Y., Chiou, H., Hsu, Y., Wu, M., Hsieh, F., Bai, C., Hsieh, Y., Chien, L., Wang, Y., Wu, M., Yang, S., Lin, Y. & Lin, C.

  3/31/15 → 12/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Chronic Renal Insufficiency 100%
  • Taiwan 77%
  • Chronic Kidney Failure 68%
  • Annual Reports 21%
  • Data Systems 19%

• The Role of Galectin-1 in Fibrosis-promoted Liver Cancer Progression

  Wu, M.

  1/1/15 → 12/31/15

  Project: A - Government Institution › a - National Health Research Institutes

  • Galectin 1 100%
  • Liver Neoplasms 33%
  • Myofibroblasts 29%
  • Fibrosis 22%
  • Liver Cirrhosis 19%

• TMU102-AE1-B25

  Chuang, J.

  1/1/14 → 12/31/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty