The Anticancer Mechanism of the Ribonucleotide Reductase Inhibiting Drug COH29 Involves Suppression of DNA Repair

Research output

Research output per year 2015 2015 2015

• 1 Article

Research output per year

Research output per year

Search results

• 2015

  The novel ribonucleotide reductase inhibitor COH29 inhibits DNA repair in vitros

  Chen, M. C., Zhou, B., Zhang, K., Yuan, Y. C., Un, F., Hu, S., Chou, C. M., Chen, C. H., Wu, J., Wang, Y., Liu, X., Smith, D. L., Li, H., Liu, Z., Warden, C. D., Su, L., Malkas, L. H., Chung, Y. M., Hu, M. C. T. & Yen, Y., Jun 1 2015, In: Molecular Pharmacology. 87, 6, p. 996-1005 10 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Repair 66%
  • DNA Damage 31%
  • N-(4-(3,4-dihydroxyphenyl)-5-phenylthiazol-2-yl)-3,4-dihydroxybenzamide 30%
  • Deoxyribonucleotides 18%
  • Antimetabolites 16%
  19 Citations (Scopus)