Additional file 1: Table S1. Meteorological and gaseous data measured by the EPA Guting air quality monitoring stations during the study period. Figure S1. Spectrums of MDA analysed by LC-MS/MS. Figure S2. Effects (3- and 6-months exposure) of PM2.5 on the inflammatory infiltration of lungs in SH rats. Subpleural alveolar infiltration of mononuclear cells was observed in the lungs after 3- and 6-months exposure of HEPA and/or PM2.5. Figure S3. Alteration in body weight of SH rats between HEPA (control) and PM2.5 (exposure) groups after 6-months exposure. Figure S4. IHC images of total Tau (t-Tau) in the cerebellum, hippocampus, and cortex of SH rats after 6 months of exposure to HEPA (control) and PM2.5 (exposure). Scar bar is 50 μm. Figure S5. Chronic effects (6-months exposure) of PM2.5 on the histological changes of cerebellum, hippocampus, and cortex in SH rats. Scale bar: 200 μm.
|Date made available||Jan 1 2020|